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Students are mentored by highly trained and specialized public health professionals. Most of the mentors teach in the Preventive Medicine Program and hold joint appointments and positions at both Upstate Medical University and the Onondaga County Health Department.

Students receive intensive one-on-one guidance and instruction with their mentor with an average of 40 hours of contact time per credit hour. Students are encouraged to conduct outside research and encouraged to think critically and independently about their research project.