Publications
Five of our lab’s most representative papers are:
- A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples.
Cohen OS, Weickert TW, Hess JL, Paish LM, McCoy SY, Rothmond DA, Galletly C, Liu D, Weinberg DD, Huang XF, Xu Q, Shen Y, Zhang D, Yue W, Yan J, Wang L, Lu T, He L, Shi Y, Xu M, Che R, Tang W, Chen CH, Chang WH, Hwu HG, Liu CM, Liu YL, Wen CC, Fann CS, Chang CC, Kanazawa T, Middleton FA, Duncan TM, Faraone SV, Weickert CS, Tsuang MT, Glatt SJ.
Molecular Psychiatry. 2016 Jul;21(7):975-82.
doi: 10.1038/mp.2015.137.
PMID: 26347318 - A polygenic resilience score moderates the genetic risk for schizophrenia.
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH); Børglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, Bækvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stefánsson H, Stefánsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ. Molecular Psychiatry. 2021 Mar;26(3):800-815.
doi: 10.1038/s41380-019-0463-8.
PMID: 31492941 - BrainGENIE: The Brain Gene Expression and Network Imputation Engine.
Hess JL, Quinn TP, Zhang C, Hearn GC, Chen S; Neuropsychiatric Consortium for Analysis and Sharing of Transcriptomes; Kong SW, Cairns M, Tsuang MT, Faraone SV, Glatt SJ.
Translational Psychiatry. 2023 Mar 22;13(1):98.
doi: 10.1038/s41398-023-02390-w.
PMID: 36949060 - A primer on the use of machine learning to distill knowledge from data in biological psychiatry.
Quinn TP, Hess JL, Marshe VS, Barnett MM, Hauschild AC, Maciukiewicz M, Elsheikh SSM, Men X, Schwarz E, Trakadis YJ, Breen MS, Barnett EJ, Zhang-James Y, Ahsen ME, Cao H, Chen J, Hou J, Salekin A, Lin PI, Nicodemus KK, Meyer-Lindenberg A, Bichindaritz I, Faraone SV, Cairns MJ, Pandey G, Müller DJ, Glatt SJ; Machine Learning in Psychiatry (MLPsych) Consortium.
Molecular Psychiatry. 2024 Feb;29(2):387-401.
doi: 10.1038/s41380-023-02334-2.
PMID: 38177352 - Novel genome-wide associations for effort valuation and psychopathology in children and adults.
Nguyen NH, Mazza TM, Hess JL, Albert AB, Elfstrom S, Forken P, Blatt SD, Fremont WP, Faraone SV, Glatt SJ. American Journal of Medical Genetics B Neuropsychiatric Genetics. 2024 Jun;195(4):e32964.
doi: 10.1002/ajmg.b.32964.
PMID: 37953388