Christopher Gaiteri, PhD

Dr. Gaiteri combines brain molecular, pathological, and imaging data to identify disease mechanisms in Alzheimer's disease.  He applies systems biology methods to identify drivers of molecular systems implicated in disease.  Dr. Gaiteri builds methods that extract molecular networks from brain omic datasets and define specific molecular control points within them.  However, this molecular analysis in Alzheimer's disease tends to operate independently of neuroimaging approaches to disease.  Therefore, we have assembled brain-based omics, fMRI, MRI, and cellular morphology data - all on the same set of individuals - which is allowing us to build a Rosetta stone of how different biophysical scales in the brain interact in health and disease.  Continuing with this theme of bringing siloed aspects of research together, Chris and his collaborators are also building collaborator recommendation systems, so that results can be repurposed across scientific fields.