Research Lab of David Auerbach, PhD
Dr. David S. Auerbach, PhD
Location: Upstate Medical University
5292 Weiskotten Hall, Syracuse, NY 13210
Phone: 315-464-7952
Email: [email protected]
Location: Upstate Medical University
5292 Weiskotten Hall, Syracuse, NY 13210
Phone: 315-464-7952
Email: [email protected]
The Auerbach Lab strives for a scientifically productive environment, through providing an inclusive and collegial environment for people to work together to advance our understanding of neuro-cardiac electrical disturbances. The group works together to mentor younger scientists, teach others new scientific approaches, and promote scientifically sound and reproducible results.
Bedside to Bench to Bedside Research Approach
Multi-System Approach to Understanding and Treating Genetic Ion Channel Diseases: The Auerbach Lab’s “Bedside-to-Bench-to-Bedside” approach to research involves clinical studies of humans with a history of electrical disturbances in the brain (seizures/epilepsy) and heart (arrhythmias). Additionally, we generated a genetic rabbit model of an inherited cardiac arrhythmia disease. It enables us to explore the underlying causes for these abnormalities by performing experiments at the molecular, biochemical, cellular, and whole animal levels. Each aspect of the research program feeds and motivates the others, creating a productive research cycle.
Recent News
- August 2024: Veronica Singh and David Auerbach author a paper in Epilepsia: Neurocardiac pathologies associated with potassium channelopathies
- October 2023: David Auerbach has been awarded over $1 million from the National Institute of Neurological Disorders and Stroke over the next three years: Groundbreaking Research Aims to Prevent SUDEP: Investigating the Link Between Epilepsy and Heart Rhythm Disorders
- August 2023: Justin Ryan, Kyle Wagner, and David Auerbach author a paper in Seizure: Heart rate and autonomic biomarkers distinguish convulsive epileptic vs. functional or dissociative seizures.
- August 2023: NIH R61/R33 IGINTE grant: Development of a Genetic Rabbit Model of Kcnh2-Mediated Epilepsy, SUDEP, & Long QT Syndrome Type-2, (1 R61 NS133273-01: PI: David S. Auerbach, PhD; Co-I: Justin M. Ryan, PhD)
- August 2023: Veronica Singh passed the qualifying exam and is now a PhD candidate.
- May 2023: Veronica Singh, Justin Ryan, and David Auerbach author a commentary paper in Epilepsia: It is Premature for a Unified Hypothesis of SUDEP: A Great Amount of Research is Still Needed to Understand the Multi-System Cascade
- April 2023: University of Rochester Clinical and Translational Science Institute (CTSI) UNYTE grant for translational science: Wearable Multi-System Recordings for Improved Disease Diagnostics (co-PI: David S. Auerbach & Inna Hughes [URMC]; Co-I: Justin M. Ryan)