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ResearchProjects in Debashis Ghosh Lab

Molecular Mechanisms of Estrogen Biosynthesis

We have been investigating the structure-function relationships and mechanisms of action of the enzymes responsible for estrogen biosynthesis and metabolism. Read more...

Characterization of the Function of Interphotoreceptor Retinoid-Binding Proteins at the Molecular Level

The structural studies to elucidate the roles interphotoreceptor retinoid-binding protein (IRBP) in vision and eye diseases pose a challenge similar in magnitude presented by aromatase.  This research is being conducted in collaboration with ophthalmologist and vision scientist Dr. Federico Gonzalez-Fernandez, Professor, SUNY Buffalo. Read more...