Molecular Pathology
Steven Sperber, MS, PhD, FACMG, Director
Phone: 315-464-8459
Email: sperbers@upstate.edu
Kristen Anderson, MT(ASCP), Supervisor
Phone: 315-464-6806
Email: anderskr@upstate.edu
Kathleen Sayles
Phone: 315 464-7147
Email: saylesk@upstate.edu
Molecular Pathology, in the Division of Anatomic Pathology at SUNY Upstate Medical University, is a DNV accredited clinical diagnostic facility which offers a growing menu of molecular testing on solid tumors.
The laboratory is currently the only laboratory with NYS approval for a variety of molecular tests. The laboratory performs PCR and FISH for adult and pediatric neoplasms including various soft tissue tumors, carcinomas and brain tumors. In addition to serving the Upstate Medical University community we are also a referral laboratory for other hospitals and clinics.
- Test Requisition
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
at 315 464-7147 or fax a request to 315 464-7130.
Submitting a Sample
- Choose appropriate test(s) from roster of tests available
- Fill out the requisition form
- Include blocks of formalin fixed paraffin embedded tissue and a copy of the Surgical Pathology report
Shipping & Handling Information
CLIA # 33D0654590
Specimen Shipping Information
- Notify the laboratory in advance of specimen arrival and/or to arrange for specimen pickup (pre-arranged courier pick up available in certain areas) by calling 315 464-7147, 315 464-7134 or Fax 315 464-7130
- The transport of specimens by overnight express courier service is preferred
Specimen Shipping Address
Upstate Medical UniversityDept. of Pathology
UH5805 750 East Adams St.
Syracuse, NY 13210
Attn: Kathleen Sayles
Supplies
To request supplies and prepaid courier air bills call 315 464-7147, Monday – Friday, 8:00 am – 4:30 pm.
Tests Available
Expand all
HER2 by FISH
| Test Includes: | HER2 Gene Amplification by FISH |
| Indications: | Breast cancer to determine prognosis and predict response to therapy |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue with the invasive tumor component. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88377 |
1p/19q Deletion by FISH
| Test Includes: | 1p/19q Deletion by FISH |
| Indications: | Oligodendroglioma, to determine prognosis and predict response to therapy. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271x2, 88291 |
SS18(SYT) Break Apart by FISH
| Test Includes: | SS18(SYT) Gene Break Apart by FISH |
| Indications: | Synovial sarcoma to facilitate diagnosis. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
EWS Break Apart by FISH
| Test Includes: | EWS gene break apart by FISH |
| Indications: | Ewings sarcoma, DSRCT (Desmoplastic small round cell tumor), Clear cell carcinoma, Extraskeletal myxoid chondrosarcoma, Myxoid/round cell liposarcoma to facilitate diagnosis. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
FOXO1(FFKHR) Gene Break Apart by FISH
| Test Includes: | FOXO1(FKHR) Gene Break Apart by FISH |
| Indications: | Alveolar rhabdomyosarcoma to facilitate diagnosis |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
EGFR Gene Amplification by FISH
| Test Includes: | EGFR Gene Amplification by FISH |
| Indications: | Lung cancer, colon cancer, glioblastoma, and response to therapy. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
DDIT3 (CHOP) Gene Break Apart by FISH
| Test Includes: | DDIT3 (CHOP) Gene Break Apart by FISH |
| Indications: | Myxoid/Round Cell Liposarcoma diagnosis. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
EGFR Gene Mutation by PCR
| Test Includes: | EGFR Gene Mutation by PCR |
| Indications: | Lung Adenocarcinoma predication of prognosis and response to therapy. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 81235, 88381 |
KRAS Gene Mutation Analysis by real-time PCR or DNA Sequencing
| Test Includes: | KRAS Gene Mutation Analysis by therascreen real-time PCR or DNA Sequencing |
| Indications: | Colon or lung adenocarcinoma, prediction of response to therapy. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 81275, 88381 |
IGH-CCND1 Gene Fusion by FISH
| Test Includes: | IGH-CCND1 Gene Fusion by FISH |
| Indications: | Mantle Cell Lymphoma Diagnosis. |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
BRAF (V600E) Mutation Analysis by PCR
| Test Includes: | BRAF (V600E) Mutation Analysis by PCR |
| Indications: | Lung, colon, and thyroid carcinoma diagnosis |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 81210, 88381 |
ALK Gene Rearrangement by FISH
| Test Includes: | ALK Gene Rearrangement by FISH |
| Indications: | Lung cancer predication of response to therapy |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |
ROS1 Gene Rearrangement by FISH
| Test Includes: | ROS1 Gene Rearrangement by FISH |
| Indications: | Lung adenocarcinoma prediction of response to therapy |
| Sample Requirements: | Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report. |
| Shipping Requirements: | Transport at room temperature. Send by overnight courier with a completed requisition form For help with this form contact: Kathleen Sayles 315 464-7147 saylesk@upstate.edu |
| Turnaround Time: | 3 - 7 days |
| CPT Code: | 88271X2, 88291 |