Shawky Badawy profile picture
315 470-7905

Shawky Badawy, MD

CURRENT APPOINTMENTS

Professor of Pathology
Division Chief of University OBGYN Associates

SPECIALTIES

Obstetrics and Gynecology
Reproductive Endocrinology and Infertility

LANGUAGES

English
Arabic

PATIENT TYPE

Adults and Children

RESEARCH PROGRAMS AND AFFILIATIONS

Obstetrics and Gynecology

RESEARCH INTERESTS

Endometriosis, infertility management, menstrual dysfunction, laparoscopic and hysteroscopic surgery, and microsurgery.

ASSOCIATIONS / MEMBERSHIPS

American College of Surgeons (ACS), Fellow
American Congress of Obstetricians and Gynecologists (ACOG), Fellow
American Society for Reproductive Medicine (ASRM), Member
North American Menopause Society (NAMS), Member
North American Society for Pediatric and Adolescent Gynecology (NASPAG), Member
Royal Society of Medicine, Fellow
Society for Reproductive Endocrinology and Infertility (SREI), Member
Society of Reproductive Surgeons (SRS), Member

EDUCATION

Residency: University Hospital, SUNY Health Science Center at Syracuse
Fellowship: Rockefeller University, 1970, Reproductive Endocrinology and Physiology
MD: Ain Shams University, Cairo, Egypt, 1958

RESEARCH ABSTRACT

Effect of Ovarian Steroids and Transforming Growth Factor Beta 1 on the Growth and Proliferation of Endometrioma Cells in Culture. With J. Holland, V. Cuenca

Endometriomas are cystic benign tumors which occur in the ovaries of women during reproductive years. Their development is initiated with ovarian steroids. However, suppression of ovarian steroids with GNRH agonist does not have an effect on the regression of these tumors. The thesis of the research is to grow the endometrioma cells in culture, to study the estrogen and progesterone receptor expression of these cells, to study the effect of various concentrations of estrogens and progesterone and transforming growth factor beta 1 on the growth and proliferation of these cells in culture. Transforming growth factor beta 1 is produced by macrophages. These macrophages have been found to be in excess in the peritoneal fluid as well as in the wall of endometriomas. This work will explain some of the factors which are involved in the development and growth of endometriomas.

Effect of Chocolate Cyst Fluid on Endometrioma Cells in Culture. With J. Holland, V. Cuenca

In this project the endometrioma cyst fluid is obtained during surgery and centrifuged to separate the supernatant fluid. It is evaluated in several ways:

  1. The effect of this fluid on growth and proliferation of endometrioma cells in culture;
  2. The contents of this fluid, specifically transforming growth factor beta 1, various interleukins, and ovarian steroids.

This will evaluate secretory functions of the endometrioma cells and the effect of those hormones and cytokines on the development and progress of endometriomas.

Effect of Pregnancy on the Natural History of Prolactin Secreting Pituitary Tumors.

Prolactin secreting pituitary tumors are considered to be the most common pituitary tumors. They are classified into microadenomas and macroadenomas. During the pregnancy there is a chance of about 5%-25% growth of the tumor. After delivery some of these tumors might remain the same size or they might regress or disappear. The natural history of this process is not known. The nature of this study is to evaluate the CT scans and MRIs of patients with prolactin-secreting pituitary tumors before and after delivery.

Selected References

Badawy, S., J. Holland, S. Landas, L. Frankel, V. Cuenca and S. Khan: The role of estradiol, progesterone, and transforming growth factor on human endometrioma cell culture. American Journal of Reproductive Immunology 36:58-63, 1996.

PUBLICATIONS

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