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Upstate Active Clinical Trials

Study Title:

INCB 18424-269 (COG AALL1521), A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib With Chemotherapy in Children With De Novo High-Risk CRLF2 Rearranged and/or JAK Pathway–Mutant Acute Lymphoblastic Leukemia

What is the purpose of the study?

This research study will find out if the study drug, ruxolitinib, in combination with standard HR B-ALL treatment is safe and effective in children, adolescents, and young adults with HR B-ALL.

Upstate Institutional Review Board (IRB) Number:


Study/Protocol ID:


Study Phase:

Phase II

Patient Age Group:


Principal Investigator:

Melanie A Comito

Who can I contact for more information?

Name: Karen B Bilynsky
Phone: 315-464-7601
Email: bilynskk@upstate.edu

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