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Upstate Active Clinical Trials

Study Title:

Transcranial magnetic stimulation for the assessment of upper motor neuron and lower motor
neuron contributions to amyotrophic lateral sclerosis (ALS)

What is the purpose of the study? (in Layman's terms, please describe the study)

Amyotrophic lateral sclerosis (ALS) is a bad disease affecting nerve cells in both the brain and the spinal cord. Much of the damage caused by this disease is to nerves involved in the control of movements. In its early stages it may affect just one part of the body, such as your speaking ability or use of one arm, but as it progresses it can result in a loss of movement (paralysis) in your arms and legs, a worsening of problems with speaking and swallowing, difficulty breathing, and eventually death. This overlap of genetic changes seen in sporadic and familial ALS raises two questions: 1) why do certain individuals who carry the genetic markers for this disease still not develop the disease? and 2) why does the severity of ALS vary so much from person to person, even those who carry the same genetic markers for ALS?

Upstate Institutional Review Board (IRB) Number:


Patient Age Group:


Principal Investigator:

Eufrosina I Young

Who can I contact for more information?

Name: Blair Calancie, PhD
Phone: 315-464-9935
Email: calancib@upstate.edu

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