Student Publications

Below are recent articles published by students in the College of Graduate Studies at SUNY Upstate Medical University. These articles appear in professional journals and books. Doctoral students who graduated from the College of Graduate Studies in the 2021-2022 academic year published on average 4.16 papers during their time at Upstate that have been cited on average 28 times. On average doctoral students graduate with 1.7 first authored papers.

2023

Eric Barnett. (2023). Analysis of the Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder Clarifies Relationship Directionality. Biol Psychiatry. 93(4):e11-e12. PMID: 36653108.
Ali Shervin Razavi. (2023). et al. Machine Learning and MRI-based Diagnostic Models for ADHD: Are We There Yet? J Atten Disord. 27(4):335-353. PMID: 36651494.
Sarah Backe, Elham Ahanin. (2023). et al. Impact of Co-chaperones and Posttranslational Modifications Toward Hsp90 Drug Sensitivity. Subcell Biochem. 101:319-350. PMID: 36520312.
Hannah Phillips. (2023). et al. Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia. Neuron. PMID: 36638803.
Fazana Tuli. (2023). et al. Chimeric a-subunit isoforms generate functional yeast V-ATPases with altered regulatory properties in vitro and in vivo. Mol Biol Cell. 1;34(3):ar14. PMID: 36598799.
Chiara Pedicone. (2023). et al. Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment. iScience. 26(2):106071. PMID: 36818285; PMCID: PMC9929608.
Singh A., Li H, Strat AN. (2023). 'Simvastatin attenuates glucocorticoid-induced human travecular meshwork cell dysfunction via YAP/TAZ inactiviation'. Curr Eye Res. pages 1 -43. PMID: 37083467
Pimm ML. (2023). 'Purification of Human β- and γ-actin from Budding Yeast'. J Cell Sci. PMID: 37070275
Zehrbach NM. (2023). 'Paxillin Regulates Rab5-mediated Vesicle Motility through Modulating Microtubule Acetylation'. Mol Biol Cell. PMID: 37043310
Waldran MJ, Wegman AD, Bahr LE. (2023).
‘Soluble NS1 Antagonizes IgG- and IgA-Mediated Monocytic Phagocytosis of DENV Infected Cells’.
J Infect Dis. PMID: 37103221
Papp C. (2023).
‘Stable Bulged G-Quadruplexes in the Human Genome: Identification, Experimental Validation and Functionalization’. Nucleic Acids Res. PMID: 37094040
Belkevich AE. (2023).'Distinct Interaction Modes for the Eukaryotic RNA Polymerase Alpha-like Subunits'. Mol Cell Biol. pages 1-14. PMID: 37222571
Khan MM, Knight K. (2023). ‘Tender love and disassembly: How a TLDc domain protein breaks the V-ATPase’. Bioessays. 15:e2200251. PMID: 37183929.
Singh V. (2023). ‘It is Premature for a Unified Hypothesis of SUDEP: A Great Amount of Research is Still Needed to Understand the Multi-System Cascade’. Epilepsia PMID: 37129136.
Bonzerato CG. (2023). ‘Bok: real killer or bystander with non-apoptotic roles? Front Cell Dev Biol’ 11:1161910 PMID: 37123400; PMCID: PMC10130511.
Heritz, JA, Wengert LA (2023). 'Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery'. Cell Rep. 42(7):112807. Epub ahead of print. PMID: 37453059.
Ahanin EF. (2023). 'Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer'. Cell Chem Biol. 14:S2451-9456(23)00206-4. PMID: 37527661.
Yang X. (2023). 'Engineering Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery'. Mol Pharm. 20(4):2138-2149. PMID: 36877183.
Namitz KEW (2023). ‘Phase Separation Promotes a Highly Active Oligomeric Scaffold of the MLL1 Core Complex for Regulation of Histone H3K4 Methylation.’ J Biol Chem. 1;:105204. PMID: 37660926

2022

Caden Bonzerato & Laura Szczesniak. (2022). et al. Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis. Front Cell Dev Biol. 10:1094302. PMID: 36601536; PMCID: PMC9806350.
Anna Maria Hinman. (2022). et al. Understanding laterality disorders and the left-right organizer: Insights from zebrafish. Front Cell Dev Biol. 10:1035513. PMID: 36619867; PMCID: PMC9816872.
Andre Grageda. (2022). et al. A Double Jeopardy: Loss of FMRP Results in DSB and Down-regulated DNA Repair. 21 Century Pathol. 2(5):125. PMID: 36688938; PMCID: PMC9850805.
Tatiana Mikhailova. (2022). et al. Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders. Mol Psychiatry
Pei-Ju Liu, Maria Presti, Eric Plante. (2022). et al. Steroid-Resistant Nephrotic Syndrome-Associated <i>MYO1E</i> Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity. J Am Soc Nephrol. 33(11):1989-2007. PMID: 36316095; PMCID: PMC9678034.
Ashley Canning. (2022). et al. Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases. Sci Rep. 12(1):18487. PMID: 36323913; PMCID: PMC9630446.
Yu Liu. (2022). et al. Deletion of POMT2 in Zebrafish Causes Degeneration of Photoreceptors. Int. J. Mol. Sci.
Haiyan Li, Ayushi Singh. (2022). et al. YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction. Invest Ophthalmol Vis Sci. 63(12):15. PMID: 36350617; PMCID: PMC9652721.
Maria Ortiz, Xiang Li, Baylee Porter-Hansen. (2022). et al. In Vivo Models for Prostate Cancer Research. Cancers (Basel). 14(21):5321. PMID: 36358740; PMCID: PMC9654339.
Mitchell Waldran, Chad Gebo. (2022). et al. Evolution of inflammation and immunity in a dengue virus 1 human infection model. Sci Transl Med. 14(668):eabo5019. PMID: 36288280.
Yu Liu. (2022). et al. Interactions between C8orf37 and FAM161A, Two Ciliary Proteins Essential for Photoreceptor Survival. Int J Mol Sci. 23(19):12033. PMID: 36233334; PMCID: PMC9570145.
Nathan McKean. (2022). et al. Coevolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance. Sci Adv. 8(36):eabq3235. PMID: 36070379; PMCID: PMC9451162.
Allen Esterly. (2022). et al. Evaluations of rationally designed rift valley fever vaccine candidate RVax-1 in mosquito and rodent models. NPJ Vaccines. 7(1):109. PMID: 36131104; PMCID: PMC9492667.
Farzana Khan, Sarah Backe. (2022). et al. Targeting extracellular Hsp90: A unique frontier against cancer. Front Mol Biosci. 9:982593. PMID: 36060252; PMCID: PMC9428293.
Sarah Backe. (2022).et al. O-GlcNAcylation suppresses TRAP1 activity and promotes mitochondrial respiration. Cell Stress Chaperones. 27(5):573-585. PMID: 35976490.
Yetunde Kayode, Deanna Clemmer. (2022). et al. mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses. Commun Biol. 5(1):878. PMID: 36028574; PMCID: PMC9412771.
Adam Wegman. (2022). et al. Fever and hypothermia do not affect the all-cause 30-day hospital readmission. Am J Med Sci. PMID: 35803309.
Allen Esterly. (2022). et al. A Human Skin Model for Assessing Arboviral Infections. JID Innov. 2(4):100128. PMID: 35812722; PMCID: PMC9256657.
Sarah Backe. (2022). et al. A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand. Cell Rep. 40(2):111039. PMID: 35830801; PMCID: PMC9306012.
Ruijia Dai. (2022). et al. Distinct Phenotypes of Inflammation Associated Macrophages and Microglia in the Prefrontal Cortex Schizophrenia Compared to Controls. Front Neurosci. 16:858989. PMID: 35844224; PMCID: PMC9279891.
Camille Chin. (2022). et al. The epigenetic reader PHF21B modulates murine social memory and synaptic plasticity-related genes. JCI Insight. 7(14):e158081. PMID: 35866480; PMCID: PMC9431697.
Justin Cox. (2022). et al. T-bet+ B cells Dominate the Peritoneal Cavity B Cell Response during Murine Intracellular Bacterial Infection. J Immunol. 208(12):2749-2760. PMID: 35867676; PMCID: PMC9309898.
Sarah Backe. (2022). et al. Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer. Biomolecules. 12(7):928. PMID: 35883484; PMCID: PMC9312812.
Alana Belkevich. (2022). et al. A clinically-relevant residue of POLR1D is required for Drosophila development. Dev Dyn. PMID: 35656583.
Morgan Pimm, Xinbei Liu, Farzana Tuli, Jennifer Heritz. (2022). et al. Visualizing molecules of functional human profilin. Elife. 11:e76485. PMID: 35666129; PMCID: PMC9249392.
Laura Szczesniak. (2022). et al. Microdose Induction of Buprenorphine in a Patient Using Tianeptine. J Addict Med. PMID: 35709488.
Xinbei Liu. (2022). et al. Multiple roles for the cytoskeleton in ALS. Exp Neurol. 355:114143. PMID: 35714755.
Michael Garone. (2022). et al. Focal segmental glomerulosclerosis and proteinuria associated with Myo1E mutations: novel variants and histological phenotype analysis. Pediatr Nephrol. PMID: 35723736
Sarah Backe. (2022).et al. TRAP1 Chaperones the Metabolic Switch in Cancer. Biomolecules. 12(6):786. PMID: 35740911; PMCID: PMC9221471.
Maria Presti. (2022). et al. Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains. EMBO Rep. 23(8):e55056. PMID: 35762418; PMCID: PMC9346500.
Caden Bonzerato. (2022). et al. Binding of the erlin1/2 complex to the third intralumenal loop of IP₃R1 triggers its ubiquitin-proteasomal degradation. J Biol Chem. 298(6):102026.
Krista Newell. (2022). et al. mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates. JCI Insight. e160039.
Krista Newell. (2022). et al. mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates. JCI Insight. e160039. PMID: 35653196.
Chiara Pedicone. (2022). et al. LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism. Front Immunol. 13:830961. PMID: 35603158; PMCID: PMC9116273.
Xiakong Guo, Caden Bonzerato. (2022). et al. Binding of the erlin1/2 complex to the third intralumenal loop of IP₃R1 triggers its ubiquitin-proteasomal degradation. J Biol Chem. 298(6):102026. PMID: 35568199; PMCID: PMC9168715.
Ana Strat, Ayushi Singh, Haiyan Li. (2022).et al. Engineering a 3D hydrogel system to study optic nerve head astrocyte morphology and behavior. Exp Eye Res. 220:109102. PMID: 35525298; PMCID: PMC9233048.
Harsimranjit Sekhon. (2022). et al. Engineering protein activity into off-the-shelf DNA devices. Cell Rep Methods. 2(4):100202. PMID: 35497497; PMCID: PMC9046454.
Alexis Zajicek, Hannah Phillips. (2022). et al. Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling. Mol Psychiatry. PMID: 35449295.
Eric Barnett. (2022). et al. Identifying pediatric mood disorders from transdiagnostic polygenic risk scores: a study of children and adolescents. J Clin Psychiatry. 83(3):21m14180.
Brittany Geiler. (2022). et al. Development of Robust Varicella Zoster Virus Luciferase Reporter Viruses for In Vivo Monitoring of Virus Growth and Its Antiviral Inhibition in Culture, Skin, and Humanized Mice. Viruses. 14(4):826. PMID: 35458556; PMCID: PMC9032946.
Krista Newell, Mitchell Waldran. (2022).et al. Simultaneous analysis of antigen-specific B and T cells after SARS-CoV-2 infection and vaccination. Cytometry A. PMID: 35468250.
Baylee Porter. (2022). et al. Evaluation of the Effect of Tobacco Use on Buccal Mucosa Graft Histology: Tobacco use does not cause histological changes in buccal mucosal grafts. Urology. PMID: 35469807.
Haiyan Li. (2022). et al. TGFβ2 regulates human trabecular meshwork cell contractility via ERK and ROCK pathways with distinct signaling crosstalk dependent on the culture substrate. Curr Eye Res. 1-41. PMID: 35481448.
Chiara Pedicone. (2022). et al. Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia. iScience.
Haiyan Li. (2022). et al. Extracellular Matrix Stiffness and TGFβ2 Regulate YAP/TAZ Activity in Human Trabecular Meshwork Cells. Front Cell Dev Biol. 10:844342. PMID: 35300422; PMCID: PMC8923257.
Md Murad Khan. (2022). et al. Oxidative stress protein Oxr1 promotes V-ATPase holoenzyme disassembly in catalytic activity-independent manner. EMBO J. 41(3):e109360. PMID: 34918374
Weiyi Xu, Kyle Alpha, Nicholas Zehrbach. (2022). et al. Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity. Mol Biol Cell. 1;33(2):ar14. PMID: 34851720
Xinbei Liu, Morgan Pimm, Andrew Brawner. (2022). et al. Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants. Eur J Cell Biol. 26;101(2):151212. PMID: 35248815
Nick Huang. (2022). et al. Mantle cell lymphoma management trends and novel agents: where are we going? Ther Adv Hematol. 13:20406207221080743. PMID: 35237397
Ishita Joshi. (2022).et al. Exceptional origin activation revealed by comparative analysis in two laboratory yeast strains. PLoS One. 17(2):e0263569. PMID: 35157703
Arnav Rana. (2022). et al. A Gravity-fed Transcardial Perfusion Method for Histologic Analysis of the Mouse Central Nervous System. J Vis Exp. ; (179). PMID: 35129175
Anna John, Harsimranjit Sekhon. (2022). et al. Engineering a Fluorescent Protein Color Switch Using Entropy-Driven Î²-Strand Exchange. ACS Sens. 7(1):263-271. PMID: 3500667
Krista Newell, Justin Cox. (2022). et al. Adenosine receptor 2a agonists target mouse CD11c +T-bet +B cells in infection and autoimmunity. Nat Commun. 13(1):452. PMID: 35064115
Rui Chen. (2022). et al. The Ets protein Pointed P1 represses Asense expression in type II neuroblasts by activating Tailless. PLoS Genet. 18(1):e1009928. PMID: 35100262
Maria Presti. (2022). et al. Mechanistic Insights into the Enhancement or Inhibition of Phase Separation by Polyubiquitin Chains of Different Lengths or Linkages. BioRxiv, Cold Spring Harbor Laboratory, Under Review.

2021

Csaba Papp, Andre Grageda, Baylee Porter, et al. ABI1-based expression signature predicts breast cancer metastasis and survival. Mol Oncol. 2021 Dec 30;. [Epub ahead of print] PMID: 34967509
Rachel Sager, et al. A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone. Transl Psychiatry. 2021 Dec 15;11(1):635. PMID: 34911938
Rebecca Harris, et al. Interleukin-2-inducible T-cell kinase (Itk) signaling regulates potent noncanonical regulatory T cells. Clin Transl Med. 2021 Dec;11(12):e625. PMID: 34919342
Mark Woodford, Sarah Backe, et al. Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint. Cell Stress Chaperones. 2021 Nov;26(6):965-971. PMID: 3458660
Adam Wegman, et al. Monomeric IgA Antagonizes IgG-Mediated Enhancement of DENV Infection. Front Immunol. 2021;12:777672. PMID: 34899736
Kevin Namitz, et al. Probing multiple enzymatic methylation events in real time with NMR spectroscopy. Biophys J. 2021 Nov 2;120(21):4710-4721. PMID: 34592262
Ana Strat, et al. Mechanosensitive channel inhibition attenuates TGFÎ²2-induced actin cytoskeletal remodeling and reactivity in mouse optic nerve head astrocytes. Exp Eye Res. 2021 Nov;212:108791. PMID: 34656548
Erin Hassett et al. Ecology of Powassan Virus in the United States. Microorganisms. 2021 Nov 9;9(11). PMID: 34835443
Gayathri Ganesh et al. Hematopoietic Stem Cells in Wound Healing Response. Adv Wound Care (New Rochelle). 2021 Sep 9;. [Epub ahead of print] PMID: 34353116
Mark Woodford, Alexander Baker-Williams, Rebecca Sager, Sarah Backe, Adam Blanden, Fiza Hashmi et al. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nat Struct Mol Biol. 2021 Aug;28(8):662-670. doi: 10.1038/s41594-021-00633-2. Epub 2021 Aug 11. PMID: 34381247.
Akshay Patel et al. Redox Control of Integrin-Mediated Hepatic Inflammation in Systemic Autoimmunity. Antioxid Redox Signal. 2021 Jul 7;. [Epub ahead of print] PMID: 34036799
Maria Presti et al. The Next Frontier for Designing Switchable Proteins: Rational Enhancement of Kinetics. J Phys Chem B. 2021 Aug 19;125(32):9069-9077. doi: 10.1021/acs.jpcb.1c04082. Epub 2021 Jul 29. PMID: 34324338
Rebecca Harris et al. Human Wnt/β-Catenin Regulates Alloimmune Signaling during Allogeneic Transplantation. Cancers (Basel). 2021 Jul 28;13(15):3798. doi: 10.3390/cancers13153798. PMID: 34359702; PMCID: PMC8345079.
Rebecca Harris et al. Targeting ITK signaling for T cell-mediated diseases. iScience. 2021 Jul 14;24(8):102842. doi: 10.1016/j.isci.2021.102842. PMID: 34368657; PMCID: PMC8326193.
Michael Jaskolka, Samuel Winkley, et al. RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification. Front Cell Dev Biol. 2021;9:698190. PMID: 34249946
Laura Szczesniak et al. Detection of carfentanil in a cluster of patients without associated mortality: Response to Chhabra et al. Am J Drug Alcohol Abuse. 2021 Jul 15;:1-2. [Epub ahead of print] PMID: 34266322
Maria Ortiz, Tatiana Mikhailova, Xiang Li, Baylee Porter et al. Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition. Cell Commun Signal. 2021 Jun 30;19(1):67. PMID: 34193161
Ishita Joshi et al. Genome-wide mapping of DNA double-strand breaks from eukaryotic cell cultures using Break-seq. STAR Protoc. 2021 Jun 18;2(2):100554. PMID: 34189468
Leonardo Dettori, Arjita Chakraborty, Csaba Papp et al. A Tale of Loops and Tails: The Role of Intrinsically Disordered Protein Regions in R-Loop Recognition and Phase Separation. Front Mol Biosci. 2021;8:691694. PMID: 34179096
Laura Szczesniak, Caden Bonzerato et al. Identification of the Bok Interactome Using Proximity Labeling. Front Cell Dev Biol. 2021;9:689951. PMID: 34136494
Adam Wegman et al. Persistent COVID-19 Symptoms Minimally Impact the Development of SARS-CoV-2-Specific T Cell Immunity. Viruses. 2021 May 15;13(5):916. doi: 10.3390/v13050916. PMID: 34063463; PMCID: PMC8155927.
Rachel Sager et al. Reduced adult neurogenesis is associated with increased macrophages in the subependymal zone in schizophrenia. Mol Psychiatry. 2021 May 31;. [Epub ahead of print] PMID: 34059796
Baylee Porter et al. Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer. Cancer (Basal). 2021 May 17;13(10):2426. doi: 10.3390/cancers13102426.
Laura Szczesniak, Caden Bonzerato et al. Bok binds to a largely disordered loop in the coupling domain of type 1 inositol 1,4,5-trisphosphate receptor. Biochem Biophys Res Commun. 2021 May 14;553:180-186. PMID: 33773141
Michael Jaskolka et al. Defining steps in RAVE-catalyzed V-ATPase assembly using purified RAVE and V-ATPase subcomplexes. J Biol Chem. 2021 Apr 22:100703. doi: 10.1016/j.jbc.2021.100703. Epub ahead of print. PMID: 33895134.
Haiyan Li, Ana Strat, Preethi Ganapathy et al. A tissue engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling. Experimental Eye Research. 2021 April.
205:108472. doi: 10.1016/j.exer.2021.108472
Kevin Namitz, Ashley Canning et al. Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism. Commun Biol. 2021 Mar 25;4(1):398. PMID: 33767358
Rebecca Harris et al. Targeting SLP76:ITK interaction separates GVHD from GVL in allo-HSCT. iScience. 2021 Mar 11;24(4):102286. doi: 10.1016/j.isci.2021.102286. eCollection 2021 Apr 23.
Ashley Sweeny-Ambros et al. Orchestrated Delivery of PTH[1-34] Followed by Zoledronic Acid Prevents Radiotherapy-Induced Bone Loss but Does not Abrogate Marrow Damage. J Orthop Res. 2022 Mar 10;. [Epub ahead of print] PMID: 35266584
Rebecca Sager, Sarah Backe, Elham Ahanin, Mark Woodford et al. Therapeutic potential of CDK4/6 inhibitors in renal cell carcinoma. Nat Rev Urol. 2022 Mar 9;. [Epub ahead of print] PMID: 35264774
Alan Blayney, Ashley Canning, Michael Connelly et al. EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction. Nat Commun. 2021 Feb 12;12(1):986. doi: 10.1038/s41467-021-21258-5. PMID: 33579943.
Alan Blayney, Adam Blanden et al. Benzothiazolyl and Benzoxazolyl Hydrazones Function as Zinc Metallochaperones to Reactivate Mutant p53. J Med Chem. 2021 Feb 4. doi: 10.1021/acs.jmedchem.0c01360. Epub ahead of print. PMID: 33538587.
Chiara Pedicone et al. Targeting SHIP1 and SHIP2 in Cancer. Cancers (Basel). 2021 Feb 20;13(4):890. doi: 10.3390/cancers13040890. PMID: 33672717; PMCID: PMC7924360.
Jamil Mahmud et al. Analysis of Cytomegalovirus Glycoprotein and Cellular Receptor Interactions. Methods Mol Biol. 2021;2244:199-211. doi: 10.1007/978-1-0716-1111-1_10. PMID: 33555588.
Rose Pasquale, Ying Guo et al. Temporal Contrast Sensitivity Increases Despite Photoreceptor Degeneration in a Mouse Model of Retinitis Pigmentosa. eNeuro. 2021 Jan 28:ENEURO.0020-21.2021. doi: 10.1523/ENEURO.0020-21.2021. Epub ahead of print. PMID: 33509952.
Morgan Pimm et al. New twists in actin-microtuble interactions. Mol Biol Cell. 2021 Feb 1;32(3):211-217. doi: 10.1091/mbc.E19-09-0491. PMID: 33507109.
Krista Newell, Yetude Kayode, Victoria Zoccoli-Rodriguez et al. Swtiched and unswitched memory B cells detected during SARS-CoV-2 convalescence correlate with limited symptom duration. PLoS One. 2021;16(1):e0244855. PMID: 33507994 [PubMed - as supplied by publisher].
Maria Presti et al. Steroid-Resistant Nephrotic Syndrome Associated MYO1E Mutations Have Differential Effects on Myosin 1E Localization, Dynamics, and Activity. BioRxiv, Cold Spring Harbor Laboratory, 1 Jan. 2021, https://www.biorxiv.org/content/10.1101/2021.11.11.468158v1.

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Student Publications of 2020

Rebecca Harris et al. Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT. Front Immunol. 2020 Nov 26;11:593863. doi: 10.3389/fimmu.2020.593863.
Adam Blanden, Alan Blayney et al. Zinc shapes the folding landscape of p53 and establishes a pathway for reactivating structurally diverse cancer mutants. Elife. 2020 Dec 2;9:e61487. doi: 10.7554/eLife.61487. Epub ahead of print. PMID: 33263541.
Adam Wegman et al. Mobilization and Activation of the Innate Immune Response to Dengue Virus. Front Cell Infect Microbiol. 2020 Nov 3;10:574417. doi: 10.3389/fcimb.2020.574417
Arijita Chakraborty et al. Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome. Cell Rep. 2020;32(12):108179. doi:10.1016/j.celrep.2020.108179
Nicholas Nguyen et al. Gene co-expression networks in peripheral blood capture dimensional measures of emotional and behavioral problems from the Child Behavior Checklist (CBCL). Transl Psychiatry. 2020;10(1):328. Published 2020 Sep 23. doi:10.1038/s41398-020-01007-w
Kyle Alpha, Weiyi Xu et al. Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion. Int Rev Cell Mol Biol. 2020;355:1-52. doi:10.1016/bs.ircmb.2020.05.003
Morgan Pimm, Jessica Hotaling et al. Profilin choreographs actin and microtubules in cells and cancer. Int Rev Cell Mol Biol. 2020;355:155-204. doi:10.1016/bs.ircmb.2020.05.005
Aaron Altman, Michael Miller & Jamil Mahmud et al. Human Cytomegalovirus-Induced Autophagy Prevents Necroptosis Of Infected Monocytes. Journal of Virology Sep 2020, JVI.0102220; doi:10.1128/JVI.01022-20
Adam Wegman et al. Serum IL-1RA levels increase from follicular to luteal phase of the ovarian cycle: A pilot study on human female immune responses. PLoS One. 2020;15(9):e0238520. Published 2020 Sep 3. doi:10.1371/journal.pone.0238520
Chiara Pedicone et al. Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis. Journal of Cell Science 2020 133: jcs238030 doi: 10.1242/jcs.238030 Published 10 January 2020.
Harsh Patel et al. Quinovic acid purified from medicinal plant Fagonia indica mediates anticancer effects via death receptor 5 [published online ahead of print, 2020 Jul 30]. Mol Cell Biochem. 2020;10.1007/s11010-020-03841-4. doi:10.1007/s11010-020-03841-4
Alexis Zajicek et al. Remodeling without destruction: non-proteolytic ubiquitin chains in neural function and brain disorders [published online ahead of print, 2020 Jul 24]. Mol Psychiatry. 2020;10.1038/s41380-020-0849-7. doi:10.1038/s41380-020-0849-7
Russell Levack, Krista Newell et al. CD11c⁺ T-bet⁺ B Cells Require IL-21 and IFN-γ from Type 1 T Follicular Helper Cells and Intrinsic Bcl-6 Expression but Develop Normally in the Absence of T-bet [published online ahead of print, 2020 Jul 17]. J Immunol. 2020;ji2000206. doi:10.4049/jimmunol.2000206
Harsh Patel et al. ECRG2, a novel transcriptional target of p53, modulates cancer cell sensitivity to DNA damage. Cell Death Dis. 2020;11(7):543. Published 2020 Jul 17. doi:10.1038/s41419-020-2728-1
Eric Zhulan, Joshua Enck et al. Reelin counteracts chondroitin sulfate proteoglycan-mediated cortical dendrite growth inhibition [published online ahead of print, 2020 Jul 8]. eNeuro. 2020;ENEURO.0168-20.2020. doi:10.1523/ENEURO.0168-20.2020
S. M. Jamil Mahmud, Michael Miller et al. Human Cytomegalovirus Mediates Unique Monocyte-to-Macrophage Differentiation through the PI3K/SHIP1/Akt Signaling Network. Viruses. 2020;12(6):E652. Published 2020 Jun 17. doi:10.3390/v12060652
Arturo Barbachano-Guerrero et al. Immunoglobulin E (IgE) Levels are associated with Kaposi's Sarcoma in HIV-Infected African Adults [published online ahead of print, 2020 Jun 19]. J Infect Dis. 2020;jiaa340. doi:10.1093/infdis/jiaa340
Allen Esterly et al. Development of a small animal model for deer tick virus pathogenesis mimicking human clinical outcome. PLoS Negl Trop Dis 14(6): 2020 Jun. e0008359. https://doi.org/10.1371/journal.pntd.0008359
Sarah Backe, Mark Woodford, Rachel Sager et al. Post-translational modifications of Hsp90 and translating the chaperone code. The Journal of Biological Chemistry. 2020 Jun. DOI: 10.1074/jbc.rev120.011833.
S. M. Jamil Mahmud, Michael Miller et al. Human Cytomegalovirus Glycoprotein-Initiated Signaling Mediates the Aberrant Activation of Akt [published online ahead of print, 2020 Jun 3]. J Virol. 2020 June;JVI.00167-20. doi:10.1128/JVI.00167-20
Fiza Hashmi et al. MMPs, tyrosine kinase signaling and extracellular matrix proteolysis in kidney cancer [published online ahead of print, 2020 May 31]. Urol Oncol. 2020;S1078-1439(20)30194-0. doi:10.1016/j.urolonc. 2020 May .04.034
Xin Wang et al. Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein [published online ahead of print, 2020 May 6]. Cell Death Differ. 2020 May; doi:10.1038/s41418-020-0549-5
Rachel Sager et al. Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors. Sci Rep. 2020 May;10(1):7795. doi:10.1038/s41598-020-64752-4
Arturo Barbachano-Guerrero et al. Detection of Antimicrobial Resistance Genes in Escherichia coli Isolated from Black Howler Monkeys (Alouatta pigra) and Domestic Animals in Fragmented Rain-Forest Areas in Tabasco, Mexico [published online ahead of print, 2020 May 13]. J Wildl Dis. 2020; doi:10.7589/2019-10-243
Jameson Patek et al. Sodium hydrogen exchanger 9 NHE9 (SLC9A9) and its emerging roles in neuropsychiatric comorbidity. Am J Med Genet B Neuropsychiatr Genet. 2020 May;183(5):289‐305. doi:10.1002/ajmg.b.32787
Mark Woodford, Sarah Backe, Rachal Sager et al. The Role of Heat Shock Protein-90 in the Pathogenesis of Birt-Hogg-Dubé and Tuberous Sclerosis Complex Syndromes [published online ahead of print, 2020 Apr 20]. Urol Oncol. 2020 Apr;S1078-1439(20)30103-4. doi:10.1016/j.urolonc.2020.03.016
Nick Huang et al. Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice [published correction appears in Lupus Sci Med. 2020 Apr;7(1). doi:10.1136/lupus-2020-000387
Xiang Li, Maria Ortiz et al. The physiological role of Wnt pathway in normal development and cancer. Experimental Biology and Medicine 2020 Mar; 0: 1–16. DOI: 10.1177/1535370220901683
Brandon Wyman et al. Metabolic pathways mediate pathogenesis and offer targets for treatment in rheumatic diseases. Curr Opin Rheumatol. 2020 Mar; 32(2):184-191. doi:10.1097/BOR.0000000000000687
Arturo Barachano-Guerrero et al. Dengue virus non-structural protein 1 activated the p38 MAPK pathway to decrease barrier integrity in primary human endothelial cells. J Gen Virol. 2020 Mar 6; doi:10.1099/jgv.0.001401
Xiakong Gao et al. The emerging link between IP 3 receptor turnover and hereditary spastic paraplegia.Cell Calcium. 2020 Mar; 86:102142. doi:10.1016/j.ceca.2019.102142
Chiara Pedicone et al. Small molecule targeting of SHIP1 and SHIP2. Biochem Soc Trans. 2020 Feb 28; 48(1):291–300. doi:10.1042/BST20190775

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Student Publications of 2019

Baylee Porter et al. Structure and Function of the Nuclear Receptor Superfamily and Current Targeted Therapies of Prostate Cancer. Cancers (Basel). 2019 Nov 23;11(12). pii: E1852. doi: 10.3390/cancers11121852. Review.
Mark Woodford et al. Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity. Oncotarget. 2019 Oct 8;10(56):5824-5834. doi: 10.18632/oncotarget.27217. eCollection 2019 Oct 8.
Maria Popescu et al. TNF-α Contributes to Lymphoid Tissue Disorganization and Germinal Center B Cell Suppression during Intracellular Bacterial Infection. J Immunol. 2019 Sep 30. pii: ji1900484. doi: 10.4049/jimmunol.1900484.
Alexander Baker-Williams et al. Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90: Client MMP2 Activity and Matrix Proteolysis. Cell Rep. 2019 Aug 13;28(7):1894-1906.e6. doi: 10.1016/j.celrep.2019.07.045.
Ashleigh Jackobel et al. DNA binding preferences of S. cerevisiae RNA polymerase I Core Factor reveal a preference for the GC-minor groove and a conserved binding mechanism. Biochim Biophys Acta Gene Regul Mech. 2019 Aug 2:194408. doi: 10.1016/j.bbagrm.2019.194408.
Cameron MacQuarrie et al. Adaptor protein Bbc1 regulates localization of Wsp1 and Vrp1 during endocytic actin patch assembly. J Cell Sci. 2019 Aug 7. pii: jcs.233502. doi: 10.1242/jcs.233502.
Jameson Patak et al. MAGEL2-Related Disorders: A study and case series. Clin Genet. 2019 Aug 9. doi: 10.1111/cge.13620.
Anna Hegsted et al. Functional importance of an inverted formin C-terminal tail at morphologically dynamic epithelial junctions. Cytoskeleton (Hoboken). 2019 Jun 19.
Maria Presti et al. A Single Protein Disruption Site Results in Efficient Reassembly by Multiple Engineering Methods. Biophys J. 2019 Jul 9;117(1):56-65. doi: 10.1016/j.bpj.2019.06.002. Epub 2019 Jun 7. PMID: 31221439; PMCID: PMC6626842.
Erica Colicino et al. Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes. Mol Biol Cell. 2019 May 1:mbcE18120817. doi: 10.1091/mbc.E18-12-0817.
Jacqualyn Schulman et al. Bok regulates mitochondrial fusion and morphology. Cell Death Differ. 2019 Apr 11. doi: 10.1038/s41418-019-0327-4.
Eric Miller et al. The carboxy-terminus of the formin FMNL1ɣ bundles actin to potentiate adenocarcinoma migration. J Cell Biochem. 2019 Apr 11. doi: 10.1002/jcb.28694.
Siyu Wei et al. Calcium-Calmodulin Gating of a pH-insensitive isoform of Connexin43 Gap Junctions. Biochem J. 2019 Mar 25. pii: BCJ20180912. doi: 10.1042/BCJ20180912.
Stuti Sharma et al. Functional reconstitution of vacuolar H+-ATPase from Vo proton channel and mutant V1-ATPase provides insight into the mechanism of reversible disassembly. J Biol Chem. 2019 Feb 21. pii: jbc.RA119.007577. doi: 10.1074/jbc.RA119.007577.
Zachary Oaks et al. Clinical utility of the cold pressor test: evaluation of pain patients, treatment of opioid-induced hyperalgesia and fibromyalgia with low dose naltrexone. Discov Med. 2018 Nov;26(144):197-206.
Rebecca Sager et al. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Rep. 2019 Jan 29;26(5):1344-1356.e5. doi: 10.1016/j.celrep.2019.01.018.
Aaron Altman et al. HCMV modulation of cellular PI3K/AKT/mTOR signaling: New opportunities for therapeutic intervention? Antiviral Res. 2019 Jan 19. pii: S0166-3542(18)30711-3. doi: 10.1016/j.antiviral.2019.01.009.
Daria LaRocca et al. Comparison of serum and saliva miRNAs for identification and characterization of mTBI in adult mixed martial arts fighters. PLoS One. 2019 Jan 2;14(1):e0207785. doi: 10.1371/journal.pone.0207785. eCollection 2019.

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Student Publications of 2018

Erica Colicino et al. Regulating a key mitotic regulator, Polo-like Kinase 1 (PLK1) Cytoskeleton (Hoboken). 2018 Nov 10. doi: 10.1002/cm.21504. [Epub ahead of print].
Rebecca Sager et al. The mTOR Independent Function of Tsc1 and FNIPs. Trends Biochem Sci. 2018 Oct 22. pii: S0968-0004(18)30203-2. doi: 10.1016/j.tibs.2018.09.018. [Epub ahead of print].
Disharee Nath et al. Identification, Histological Characterization, and Dissection of Mouse Prostate Lobes for In Vitro 3D Spheroid Culture Models.J Vis Exp. 2018 Sep 18;(139). doi: 10.3791/58397.
Shangdong Guo et al. Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4α J Cell Biochem. 2018 Sep 7. doi: 10.1002/jcb.27407. [Epub ahead of print]
Xian Zhang et al. Differences in Functional Expression of Connexin43 and NaV1.5 by Pan- and Class-Selective Histone Deacetylase Inhibition in Heart. Int J Mol Sci. 2018 Aug 4;19(8). pii: E2288. doi: 10.3390/ijms19082288. [Epub ahead of print]
Forrest Wright et al. The erlin2 T65I mutation inhibits erlin1/2 complex mediated-inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding. J Biol Chem. 2018 Aug 22. pii: jbc.RA118.004547. doi: 10.1074/jbc.RA118.004547. [Epub ahead of print]
Megan Peppenelli et al. Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes. Antiviral Res. 2018 Jul 25;158:13-24. doi: 10.1016/j.antiviral.2018.07.015. [Epub ahead of print]
Scott Michenberg et al. Systemic lupus erythematosus-myasthenia gravis overlap syndrome: Presentation and treatment depend on prior thymectomy. Clin Immunol. 2018 Sep;194:100-104. doi: 10.1016/j.clim.2018.07.007. Epub 2018 Jul 17. [Epub ahead of print]
Kevin Kenderes et al. T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells. Cell Rep.2018 Jul 24;24(4):824-837.e3. doi: 10.1016/j.celrep.2018.06.074 [Epub ahead of print]
Saptarshi Biswas et al. Laminin-dystroglycan signaling regulates retinal arteriogenesis. FASEB J. 2018 Jun 6;:fj201800232R. [Epub ahead of print]
Dmitri Serjanov et al. Laminin β2 Chain Regulates Retinal Progenitor Cell Mitotic Spindle Orientation via Dystroglycan. J Neurosci. 2018 May 31. pii: 0551-18. doi: 10.1523/JNEUROSCI.0551-18.2018. [Epub ahead of print]
Heather Nelson et al. Interplay between ER Ca²⁺ Binding Proteins, STIM1 and STIM2, Is Required for Store-Operated Ca²⁺ Entry. Int J Mol Sci. 2018 May 19;19(5).
Stuti Sharma et al. MgATP hydrolysis destabilizes the interaction between subunit H and yeast V1-ATPase, highlighting H's role in V-ATPase regulation by reversible disassembly. J Biol Chem. 2018 May 12;. [Epub ahead of print]
Anushree Gulvady et al. Hic-5 Expression is a Major Indicator of Cancer Cell Morphology, Migration and Plasticity in Three-Dimensional Matrices. Mol Biol Cell. 2018 May 17:mbcE18020092. doi: 10.1091/mbc.E18-02-0092. [Epub ahead of print]
Nick Huang et al. Metabolism as a Target for Modulation in Autoimmune Diseases. Trends Immunol. 2018 May 5;. [Epub ahead of print]
Rebecca Sager et al. Sporadic renal angiomyolipoma in a patient with Birt-Hogg-Dubé: chaperones in pathogenesis. Oncotarget. 2018 Apr 24;9(31):22220-22229.
Adam Wegman et al. HIV Infection: Antepartum Treatment and Management. Clin Obstet Gynecol. 2018 Mar;61(1):122-136. doi: 10.1097/GRF.0000000000000330. PMID: 29309283.
Mansi Babbar et al. CHTM1, a novel metabolic marker deregulated in human malignancies. Oncogene [Epub ahead of print].
Agnik Dasgupta et al. Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer's vesicle. Elife Jan 29;7, 2018.
Gregory J Goreczny et al. Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1. Oncogene [Epub ahead of print]
Shangdong Guo et al. Conjunction of G-quadruplex and stem-loop in the 5' untranslated region of mouse hepatocyte nuclear factor 4-alpha1 mediates strong inhibition of protein expression. Mol Cell Biochem. [Epub ahead of print]
Renyan Liu et al. Monoglyceride lipase gene knockout in mice leads to increased incidence of lung adenocarcinoma. Cell Death Dis. 9(2):36, 2018.
Samuel J. Mackenzie et al. Cauda equina repair in the rat: Part 3. Axonal regeneration across Schwann cell seeded collagen foam. Muscle Nerve 57(1):E78-E84, 2018.
Heather Nelson et al. Molecular physiology and pathophysiology of stromal interaction molecules. Exp Biol Med [Epub ahead of print]
Rebecca A. Sager et al. Detecting Posttranslational Modifications of Hsp90. Methods Mol Biol. 1709:209-219, 2018.
Marissa Smith et al. Reconstitution of RNA Polymerase I Upstream Activating Factor and the Roles of Histones H3 and H4 in Complex Assembly. J Mol Biol. [Epub ahead of print]