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Graduate Studies Faculty

Chunyu Liu, PhD

Chunyu Liu, PhD
Appointed 12/01/17
3704 Institute For Human Performance (IHP)
505 Irving Avenue
Syracuse, NY 13210

315 464-3448

Current Appointments

Hospital Campus

  • Downtown

Research Programs and Affiliations

  • Biomedical Sciences Program
  • Neuroscience Program
  • Psychiatry and Behavioral Sciences

Education & Fellowships

  • PhD: Hunan Medical University, Hunan, China, 1998, Medical Genetics

Previous Appointments

  • University of Chicago, 1998–2011
  • University of Illinois at Chicago, 2011–2017

Clinical Interests

  • Developing more objective diagnosis of psychiatric disorders

Education Interests

  • Training young scientistis with passion and interests to work for improving human life and health.

Research Interests

  • Dr. Liu's major research focuses on identifying the molecular mechanisms of major psychiatric diseases, particularly bipolar disorder and schizophrenia using  comprehensive approaches including genetics, bioinformatics, genomics, cellular and animal models.

Diseases & Conditions Treated

  • Bipolar Disorders
  • Psychotic Disorders
  • Schizophrenia


  • American College of Neuropsychopharmacology
  • American Society of Human Genetics (ASHG)
  • International Society of Psychiatric Genetics (ISPG)

Languages Spoken (Other Than English)

  • Chinese


Dr. Liu has a long-term interest in understanding of molecular basis of psychiatric diseases. His laboratory participated in one of the bipolar genetics research consortiums and discovered the rare copy number variant (CNV) burden in early-onset bipolar disorder. His lab is one of the leading research groups on genome-wide study of postmortem brain gene expression and DNA methylation, pioneered in study of gene expression regulatory network in human brain. He established the methylation quantitative trait loci (mQTLs) in human brain, indicating that DNA methylation of some sequences could be highly regulated by genetic variants. His lab currently focuses more on understanding genomic and epigenomic mechanisms in human brains for psychiatric disorders. His research has been supported by NIMH, NARSAD, and Brain Research Foundation. He has published more than 100 peer-reviewed papers and several book chapters, and been cited for more than 7,000 times, with H-index of 37. He has served as reviewer for dozens of journals and foundations including NIH. Dr. Liu’s major research focuses on using a comprehensive approach that is composed of genetics, bioinformatics, genomics, cellular and animal models to identify the molecular mechanisms of major psychiatric diseases, particularly bipolar disorder and schizophrenia. Constructing multidimensional regulatory network in human brains, and relating that to etiology and pathology of mental illness is the major mission of this lab.

Current major NIH-funded project is the psychENCODE project, investigating multi-dimensional biological features, networks in brains of bipolar disorder, schizophrenia and normal.


Faculty Profile Shortcut: https://www.upstate.edu/faculty/liuch