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Nephrogenic Diabetes Insipidus (DI)

Nephrogenic DI is actually a group of conditions in which the kidney is unable to concentrate the urine. This results in a continued high output of urine, sometimes leading to dehydration. Sometimes, the first sign of nephrogenic DI is bedwetting, although the large majority of children with simple bedwetting do not have a serious underlying condition.

Nephrologists diagnose and treat children with all forms of DI. Usually, testing involves blood and urine studies, as well as some xrays.  Rarely, children are admitted to the hospital for more detailed testing. The treatment of nephrogenic DI depends upon the cause, but all children with the condition require regular visits to nephrologists. It is particularly important for nephrologists to see them during any illness which interferes with their ability to drink or hold down fluids.