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Recent Publications

Membrane-cytoskeleton mechanical feedback mediated by myosin-I controls phagocytic efficiency. S. R. Barger, N. S. Reilly, M. S. Shutova, Q. Li, P. Maiuri, M.S. Mooseker, R. A. Flavell, T. Svitkina, P. W. Oakes, M. Krendel, N. Gauthier.  Nature Communications, 10(1):1249, 2019.

Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes. Y. Zhang, F. Cao, Y. Zhou, Z. Feng, B. Sit, M. Krendel, C. Yu. MBoC. 30(5):622-635, 2019.

Myosin-1E interacts with FAK proline rich region 1 to induce fibronectin-type matrix. J. B. Heim, E.J. Squirewell, A. Neu, G. Zocher, S. Sominidi-Damodaran, S.P. Wyles, E. Nikolova, N. Behrendt, D.M. Saunte, J. Lock-Andersen, K.S. Gaonkar, H. Yan, J.N. Sarkaria, M. Krendel, J. van Deursen, R. Sprangers, T. Stehle, R.T. Böttcher, J. Lee, T. Ordog, A. Meves.  Proc Natl Acad Sci U S A. 114(15):3933-3938, 2017.

Hic-5 remodeling of the stromal matrix promotes breast tumor progression. G.J. Goreczny, J.L. Ouderkirk-Pecone, E.C. Olson, M. Krendel, C.E. Turner. Oncogene. 36(19):2693-2703, 2017.

Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury. M.J. Randles, S. Collinson, T. Starborg, A. Mironov, M. Krendel, E. Königshausen, L. Sellin, I.S. Roberts, K.E. Kadler, J.H. Miner, R. Lennon. Sci Rep. 2016 Oct 11;6:35068. doi: 10.1038/srep35068.

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell differentiation. J.L. Ouderkirk-Pecone, G.J. Goreczny, S.E. Chase, A.H. Tatum, C.E. Turner, M. Krendel. Oncotarget.7(29):46419-46432, 2016.

Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast. J. Bi, R.T. Carroll, M.L. James, J.L. Ouderkirk, M. Krendel, V. Sirotkin. Dis Model Mech. 8:891-902, 2015.

A novel suspended hydrogel membrane (ShyM) platform for cell culture. Y. X. Chen, S. Yang, J. Yan, M. Hsieh, L. Weng, J.L. Ouderkirk, M. Krendel, P. Soman. ASME – Journal of Nanotechnology in Engineering and Medicine, 6(2), 2015.

The class I myosin Myo1e regulates TLR4-triggered macrophage spreading, chemokine release and antigen presentation via MHC class II. J. Wenzel, J.L. Ouderkirk, M. Krendel, R. Lang. Eur J Immunol. 45:225-37, 2015.

Non-muscle myosins in tumor progression, cancer cell invasion and metastasis. J.L. Ouderkirk, M. Krendel. Cytoskeleton, 71:447-63, 2014.

Myosin 1e is a component of the invadosome core that contributes to regulation of invadosome dynamics.
Ouderkirk JL, Krendel M.
Exp Cell Res. 2014 Apr 1;322(2):265-76.

Visualization of cytoskeletal dynamics in podocytes using adenoviral vectors.
Bi J, Pellenz CD, Krendel M.
Cytoskeleton. 2014 Mar;71(3):145-56.

Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes.
Bi J, Chase SE, Pellenz CD, Kurihara H, Fanning AS, Krendel M.
Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F532-44.

Podocyte-specific knockout of myosin 1e disrupts glomerular filtration.
Chase SE, Encina CV, Stolzenburg LR, Tatum AH, Holzman LB, Krendel M.
Am J Physiol Renal Physiol. 2012 Oct;303(7):F1099-106.

MYO1E Mutations and Childhood Familial Focal Segmental Glomerulosclerosis.
Mele C, Iatropoulos P, Donadelli R, Calabria A, Maranta R, Cassis P, Buelli S, Tomasoni S, Piras R, Krendel M, Bettoni S, Morigi M, Delledonne M, Pecoraro C, Abbate I, Capobianchi MR, Hildebrandt F, Otto E, Schaefer F, Macciardi F, Ozaltin F, Emre S, Ibsirlioglu T, Benigni A, Remuzzi G, Noris M. N Engl J Med. 2011 Jul 28;365(4):295-306.

Myo1e binds anionic phospholipids with high affinity.
E.A. Feeser, C.M. Ignacio, M. Krendel, and E.M. Ostap. Biochemistry, 49:9353-60, 2010.

Disruption of Myosin 1e promotes podocyte injury.
M. Krendel, S.V.Kim, T. Willinger, T. Wang, M. Kashgarian, R.A. Flavell, and M.S. Mooseker. JASN, 20:86-94, 2009.

Link to complete Pubmed bibliography