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Testicular Cancer

Testicular cancer is treated in our Urologic Cancer Program within the Upstate Cancer Center.

For more information or answers to your questions about our Cancer Care, please call 315 464-HOPE (4673) to speak with an Upstate Cancer Center representative.


Testicular cancer is a growth of cancer cells in one or both testicles. The testicles are a pair of male sex glands. They make and store sperm and male hormones. Types of testicular cancer include:

  • Seminomas
  • Non-seminomas (embryonal cell carcinoma, teratomas, and choriocarcinoma)
  • Stromal cell tumors


Cancer occurs when cells in the body divide without control or order. They grow to form a tumor. These growths can invade nearby tissue and can later spread to other areas of the body.

It is not clear what the exact cause is. Genetics and environment may both play a role.

Risk Factors

Testicular cancer is more common in men aged 25 to 35. Other things that may increase your chance of testicular cancer are:

Undescended Testes
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Testicular cancer may cause:

  • A painless lump or swelling in either testicle
  • Swelling of a testicle or change in the way it feels
  • Feeling of heaviness in the scrotum
  • A dull ache in the lower belly or groin
  • Sudden appearance of fluid in the scrotum
  • Pain or discomfort in a testicle or in the scrotum
  • Lower back pain
  • Growth of breast not due to weight gain

Early diagnosis will improve outcomes. Your doctor may do testicular exams at check ups. They may also talk about self examinations to look for any changes. Changes should be checked out by a doctor.


The doctor will ask about your symptoms and past health. A physical exam will be done. Your doctor may order:

  • Blood tests
  • Ultrasound—to find or examine growths
  • Biopsy—small piece of tissue is removed and looked at in lab

More tests may be done once cancer is found:

The tests will help to find the type and stage of cancer. Staging is used to guide a treatment plan. Testicular cancer is stage 1 to 3. Stage 1 cancer is only in local tissue. Stage III cancer has spread to other parts of the body.


Cancer treatment will be based on the stage and type of cancer. The plan will often have more than one type of therapy. Steps may include:


The goal is to remove as much cancer as possible. Some local healthy tissue may also be removed. Lymph nodes in the area may also need to be removed. They may be tested for cancer. More nodes may be removed if cancer is found in the nodes.

Radiation Therapy

Radiation therapy will kill cancer cells and shrink tumors. It may be used on the area after surgery. It can help to kill any cancer cells that could not be seen. It may also be used to treat tumors that are causing problems but cannot be removed with surgery.


Chemotherapy is the use of drugs to kill cancer cells. It may be given as pills, injections, or by IV. The drugs travel through the body. The drugs targets cancer cells, but some healthy cells can be damaged as well. It may be used along with radiation therapy for some types of testicular cancers. It may also be used for cancer that has spread.

Treatment can cause fertility problems. Sperm banking and other treatments may help.

Treatment can cause fertility problems. Sperm banking and other treatments may help.


There are no steps for testicular prevention in most men.


Library resources related to testicular cancer.

For more information:

Internet Links
The detailed guide includes descriptions of causes, risk factors, prevention, diagnosis, staging, and treatments and what's new in testicular cancer research..
Approved drugs for treatment of testicular cancer from the National Institute of Health's National Cancer Institute.
Health information on testicular cancer from the Mayo Clinic Foundation, includes: description, symptoms, causes, risk factors, tests and diagnosis, treatments and drugs, prevention, and coping and support.
Link to a search of the MedlinePlus database for health information on testicular cancer. MedlinePlus links are managed by medical librarians at the National Library of Medicine.
Links to information from the National Cancer Institute on treatment, clinical trials, prevention, genetics, causes, cancer research, and screening.