 Bernard J Poiesz, M.D.Professor, Medicine 1239 Weiskotten Hall Research Program and Department AffiliationsMedicine, Professor Research InterestsDetection, quantification, and characterization of human retro-viruses, testing of antiviral compounds; understanding the biology of sarcomeric protiens. Our laboratory''s primary focus is the detection, quantification, and characterization of human retroviruses. Studies also involve the in vitro and in vivo testing of antiviral compounds. A secondary focus is the role of sarcomeric proteins in cardiomyocyte and cancer cell biology.Selected References Poiesz, B.J., Papsidero, L.D., Eherlich, G., Sherman, M., Dube, S., Poiesz, M., Dillon, K., Ruscetti, F.W., Slamon, D., Fang, C., Williams, A., Duggan, D., Glaser, J., Gottlieb, A., Goldberg, J., Ratner, L., Phillips, P., Han, T., Friedman-Kein, A., Siegal, F., Rai, K., Sawitsky, A., Sheremata, L.W.A., Dosik, H., Cunnighham, C., and Montagna, R.: Prevalence of HTLV-I associated T-cell lymphoma. Amer J Hemat 66: 32-38, 2001. Poiesz, B.J., Poiesz, M.J., and Choi, D.: The human T-cell lymphoma/ leukemia viruses. Cancer Investigation. 21: 247-271, 2003. Ferrer, J.F., Esteban, E., Murua, A., Gutierrez, S., Dube, S., Poiesz, B.J., Feldman, L., Basombrio, M.A., Galligan, D.: Association and epidemiological features of Trypanosoma cruzi and human T-cell lymphoma virus type II in inhabitants of the Paraguayan Gran Chaco. Ann. J. Trop Med. Hyg. 68: 235-241, 2003. Zajdel, R.W., Denz C.R., McLean M.D., Dube S., Muthuchamy M., Poiesz B.J., Wieczorek D.F., Dube D.K.: Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins. Cardiac Toxicology, 5: 75-90, 2005. Zajdel, R.W., McLean, M.D., Denz C.R., Dube S., Thurston H.L., Poiesz B.J., Dube D.K.: Differential expression of tropomyosin during segmental heart development in Mexican Axolotl. J Cellular Biochemistry, 99: 952-965, 2006. Walter M. Stadler, Apurva Desai, David Quinn, Ronald Bukowski, B. Poiesz?, C. Kardinal, N. Lewis, A.. Makalinao, Peter Murray, David Quinn, Frank Torti: A Phase I/II Study of GTI-2040 and Capecitabine in Patients with Renal Cell Carcinoma. Cancer Chemotherapy and Pharacology. (in press) Publications- link to PubMedNote: The above PubMed link opens a new window. Close the PubMed window to return to this page. Additional InformationChief, Division of Hematology/Oncology, Department of Medicine This profile was last updated on 07/29/2009 A short link is available for this profile: http://www.upstate.edu/faculty/?ID=poieszb Back to Faculty Research @ Upstate Page |