POSTDOC PROFILES
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Reyna Martinez-De Luna, PhD

"I chose Upstate because I was very impressed with the Center for Vision Research..."
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Postdoc Positions




Helene Bernstein , MD/PhD

Associate Professor, Obstetrics and Gynecology

Highly motivated candidate with a PhD degree (or equivalent) in a relevant scientific disciple, including microbiology, molecular biology, immunology, and/or cell biology is required. Experience with flow cytometric analysis and primary cell culture is preferred, but not a prerequisite.  A strong record of scientific excellence as evidence by lead author publication in peer-reviewed scientific journals is a plus.

The successful candidate will be successful at working independently on projects related to immunopathogenesis.  Projects will be focused on the role of magnesium in reducing inflammation, influencing injection, and modulating immune cell function.  The postdoc will be expected to work with HIV and rodent modules of infection, becoming facile at assessing human and mouse immunopathogenesis.  Preference will be given to individuals with experience in the above areas and a demonstrated ability to lead a project, analyze and organize data and write manuscripts.

Derek Cooney , MD, FF/EMT-P, FACEP

Associate Professor, Emergency Medicine

EMS Medicine Fellowship: Currently accepting applications for our ACGME-accredited EMS Medicine Fellowship program.  Contact Lisa Williams, Program Coordinator, with interest (williaml@upstate.edu) (315) 464-4851. 

Steven Hanes , PhD

Professor, Biochemistry and Molecular Biology

 

William Kerr , PhD

Professor, Microbiology and Immunology

Post-doctoral positions available in the laboratory of William G. Kerr, Ph.D. (Depts. of Microbiology & Immunology and Pediatrics, SUNY Upstate).  Candidates are sought for ongoing NIH funded projects concerning the role of inositol phospholipid signaling in: (1) hematologic and breast neoplasms [J. Immunology 184: 3582-3889 (2010)], (2) Crohn's disease and inflammatory bowel disease  [ Gut 60:  177-88 (2011)]  (3) immune regulation  [ SCIENCE 295, 2094-2097 (2002), J. Immunology 176, 7165-69 (2006); Blood 113:  2934-44 (2009)] and (4) stem cell biology [BLOOD 98, 2028-2038 (2001); 107, 4338-45, 2006; 113:  2924-33 (2009)].  In addition to mechanistic studies devoted to the above questions, there is also significant potential for translational research and participation in commercial ventures.  For further information or to apply, please contact William G. Kerr:  kerrw@upstate.edu

Yahia Lodi , MD, FAHA

Professor, Clinical Campus - Neurology

Endovascular Surgical Neuroradilogy Fellowship: Tow years fellowship dedicated towards obtaining clinical knowledge and technical skills in the diagnosis, decision macking, endovascular treatment and long-term followup of  acute ischemic Stroke/intervention, extracranial and intracranial carotid, vertebral and basilar artery stenosis/angioplasty and stenting, embolization of cerebral aneurysm with or without stent, embolization of arteriovenous malformation (AVM), arteroivenous fistula (AVF) and brain tumor, treatment of cerebral vasospasm and delivery of pharmacological agents to the brain vascular beds.

Fellows will have an opportunities to participate in the clinical trials and clinical ourcome studies of stroke, aneurysms and vascular malformations

Email:  lodiy@upstate.edu

Golam Mohi , PhD

Associate Professor, Pharmacology

A Postdoctoral Research Associate position is available in the laboratory of Dr. Golam Mohi at the State University of New York, Upstate Medical University to study the molecular and epigenetic mechanisms of myeloid leukemia. The project offers unique opportunity to utilize state-of-the-art techniques and genetically engineered mouse models to uncover the mechanisms involved in leukemogenesis. Please see some of our recent publications-

1. Yang et al. Blood 2016 Apr 14; Epub ahead of Print

2. Yan et al. Leukemia 2015, 29(10):2050-2061

3. Akada et al. Stem Cells 2014, 32(7):1878-1889

4. Akada et al. Leukemia 2014, 28(8):1627-1635

5. Yan et al. Blood 2012, 119(15):3539-3549

6. Akada et al. Blood 2012, 119(16):3779-3789.

Candidates should have a recent Ph.D. or MD/PhD degree with a strong background in molecular biology, cell biology, immunology or related field. Candidates must have a proven track record in research with first author publications in reputed journals. Experience in flow cytometry, animal handling and hematopoiesis studies will be preferred. Applicants should send a cover letter, curriculum vitae, a summary of research experience and the names and contact information (e-mail and telephone numbers) of three references to Dr. Golam Mohi at mohim@upstate.edu

 

 

Andras Perl , MD, PhD

Professor, Medicine

Interested applicant should send curriculum vitae and names, addresses, and telephone numbers of three references by e-mail to perla@upstate.edu

Brief Research Description
1. Genetic and Immunological impact of the HRES-1 endogenous retrovirus in Systemic Lupus Erythematosus
Genetic and environmental factors mediate the development of autoimmune diseases, such as systemic lupus erythematosus (SLE). We have identified polymorphic genotypes of the HRES-1 endogenous retrovirus, located on human chromosome 1 band q42, that influence autoimmunity in SLE. Inheritance of HRES-1 alleles in lupus families is investigated. Our recent data suggest that a small GTP-ase encoded by HRES-1, termed HRES-1/Rab4 influences the recycling of cell surface receptors, such as CD4 and the T-cell receptor zeta chain, and may contribute to abnormal T-cell activation in lupus by influencing T-cell synapse formation via receptor recycling.

2. Metabolic control of systemic autoimmunity
This project investigates the role of mitochondrial dysfunction in aberrant activation and death signal processing in lupus T cells. In particular, metabolic pathways affecting nitric oxide production, glutathione metabolism, and the mammalian target of rapamycin are being investigated.

3. Regulation of Autoimmunity & Tumorigenesis by Transaldolase via Metabolic Control of Programmed Cell Death
Defects of apoptosis, a form of programmed cell death, underlie the causation of cancer, and autoimmune diseases. We have discovered and molecularly cloned human transaldolase (TAL) as an autoantigen and metabolic regulator of apoptosis. TAL is highly expressed in oligodendrocytes of the brain which are selectively targeted by autoreactive T cells and antibodies in patients with multiple sclerosis. Presently, we analyze the impact of TAL deficiency in humans and knock-out mice developed in the laboratory.

Recent Publications available here:

http://www.ncbi.nlm.nih.gov/pubmed?dispmax=20&pmfilter_EDatLimit=No%20Limit&cmd_current=Limits&orig_db=PubMed&cmd=Search&term=perl%20a%20and%20syracuse&doptcmdl=DocSum


Christopher Turner , PhD

Distinguished Professor, Cell and Developmental Biology

Postdoctoral postions are available. Please submit a letter of interest along with a copy of your CV and research experience/interests to Dr. Turner

Andrea Viczian , PhD

Assistant Professor, Ophthalmology

A postdoctoral position is now open in the Viczian laboratory, which  studies how pluripotent cells, like stem cells, develop and differentiate into retinal cone photoreceptor cells. The successful  candidate will study the signaling pathways and molecular mechanisms  that are necessary to form these sight-saving cells. They will have a PhD in biochemistry/molecular biology or neuroscience; a background in  stem cell biology is preferred but those with mammalian cell culture  experience will still be considered. The Viczian laboratory is one of  three groups, which are working side-by-side to understand eye  formation in three model organisms: fly, frog and mouse. We are part  of a bigger group, the Center for Vision Research, which is the  research arm of the Ophthalmology Department at Upstate Medical  University. This opportunity will include training of the candidate so  that they may pursue a future career as an independent PI. Candidates  should send a current curriculum vitae, three references with contact information and a cover letter describing their interest in the  project to vicziana@upstate.edu. Please include "Postdoc" in the  subject of your email.

Gary Winslow , PhD

Professor, Microbiology and Immunology

A Postdoctoral position is available in the laboratory of Dr. Gary Winslow, to study the genesis, differentiation, and maintenance of IgM memory B cells during infection.

http://www.upstate.edu/microb/research/faculty-profile.php?empID=winslowg

The work in our laboratory is largely focused on studying memory B cells in a model of bacterial infection caused by obligate intracellular bacteria of the genus ehrlichia. Antibodies are essential for immunity in our infection model, so our work has emphasized the activities of B cells. We are investigating a large and novel population of IgM memory B cells that are elicited during infection and that are responsible for recall responses to secondary antigen challenge. We are particularly interested in how the differentiation and repertoire of these non-switched memory cells differ from that of conventional switched memory cells, the role of IgM memory cells during secondary infection, and how we can elicit these cells by vaccination.

An ideal candidate will have a strong research background in basic cellular immunology. Applicants should have obtained a PhD degree and completed fewer than three years of post-doctoral experience.

Upstate Medical University provides an excellent research environment. The Department of Microbiology and Immunology is currently undergoing a major expansion of faculty and resources.

A complete list of published work from Dr. Winslow’s laboratory can be found at:
http://www.ncbi.nlm.nih.gov/sites/myncbi/gary.winslow.1/bibliography/40495498/public/?sort=date&direction=ascending.

Applications should be emailed to Gary Winslow at winslowg@upstate.edu
     

Yunlei Yang , MD, PhD

Assistant Professor, Neuroscience and Physiology

Postdoctoral positions are currently available. We are seeking candidates who have a background in electrophysiology with interests in neurobiology. If you are interested, please send your electronic CV (curriculum vitae) to Yunlei Yang (yangyun@upstate.edu).

All applications should include the following:

1. Cover letter indicating current and future research interests and expected availability date

2. CV (Curriculum Vitae)

3. Description of past research experience and accomplishments

4. Selected reprints of publications

5. Names of three references

Wei-Dong Yao , PhD

Associate Professor, Psychiatry and Behavioral Sciences

Postdoctoral positions are available to study molecular, cellular, and circuit mechanisms in the prefrontal cortex that regulate reward, executive, and social behavioral function as well as related mental diseases such as addiction, autism, and dementia. Prospective candidates will apply cellular electrophysiology, viral-mediated gene delivery, and optogenetic techniques in brain slices from transgenic mice deficient in emerging microRNA and other novel pathways that regulate synapse assembly, function, and plasticity. A Ph.D. and/or M.D. degree in related fields is required and prior experience in patch-clamp and/or intracellular recordings is highly desirable. Interested candidates should submit a curriculum vitae and contact information for three references to Dr. Wei-Dong Yao, State University of New York, Upstate Medical University, Syracuse, NY via email to yaow@upstate.edu.

Li-Ru Zhao , PhD

Associate Professor, Neurosurgery

There are 2 Postdoctoral Associate positions available:

Position 1: 

Basic requirements: Highly self-motivated and productive individuals with a PhD degree in Neuroscience. Experience in traumatic brain injury and/or stroke with related publications.

Specific job skills:

1. Make a mouse model of traumatic brain injury and/or stroke.

2. Preform neurobehavioral testing such as water maze, elevated plus maze, novel object recognition, Rota-Rod, and forced swimming.

3. Preform bone marrow isolation and bone marrow transplantation, blood collection, flow cytometry, 2-photon live brain imaging, confocal imaging, brain sectioning, and immunohistochemistry.

4.Inject cells or drugs subcutaneously, intravenously or intracerebrally.

5. Have experience in tissue gene expression and protein quantification, cell adhesion and cell-cell interaction.

6.Preform CLARITY and whole brain imaging.

7.   Analyze research data and write research manuscripts.

8. Have good communication skills.

  

Position 2:  

Basic requirements: Highly self-motivated and productive individuals with a PhD degree in Neuroscience and/or stem cell biology. Experience in molecular biology, and/or traumatic brain injury/stroke with related publications.

Specific job skills:

1.  Isolate neurons from mouse embryonic brain and isolate bone marrow monocytes, and culture the primary cells.

2.  Identify cell signal pathway, and quantify gene expression and protein production.

3.  Have experience in gene knock in and knock down.

4.   Perform live cell imaging and confocal imaging.

5.  Isolate and identify microvesicles and exosomes.

6.  Examine neurite outgrowth, synaptic formation and maturation, cell adhesion and migration, and cell-cell interaction.

7.  Analyze research data and write research manuscripts.

8. Have good communication skills.