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Peer-Reviewed Publications

2022

  • Field AM, Seabury RW, Kufel WD, Darko W, Miller CD, Mastro KA, Steele JM. Single-dose antibiotic prophylaxis with ertapenem increases compliance with recommendations for surgical antibiotic prophylaxis in elective colorectal surgery: A retrospective, single center analysis. Surgical Infections, 2022. Epub ahead of print.
  • Hitchcock AM, Seabury RW, Kufel WD, Farooqi S, Steele JM, Darko WD, Miller CD, Feldman EA. Does a positive methicillin-resistant Staphylococcus aureus (MRSA) nasal screen predict the risk for MRSA skin and soft tissue infection? Annals of Pharmacotherapy. 2022. Epub ahead of print.
  • Chen D, Seabury RW, Steele JM, Darko W, Miller CD, Kufel WD. Evaluation of B-lactam therapeutic drug monitoring among UH health systems with postgraduate year 2 infectious diseases pharmacy residency programs. Am J Health-syst Pharm. 2022. Epub ahead of print.
  • Cheung NC, Noviasky JA, Ulen KR, Brangman SA. Efficacy and safety of megestrol in the hospitalized older person. Sr Care Pharm. 2022: 1;37(7):284-292
  • Yuksel JM, Brenner JM, Britton S, Bhatti H, Noviasky J. Optimal injectable haloperidol dose assessment in the older hospitalized inpatient. Ann Pharmacotherapy. 2022. Epub ahead of print.
  • Yuksel JM, Noviasky J, Britton S. Aducanumab for Alzheimer’s Disease: Summarized data from EMERGE, ENGAGE, and PRIME studies. Sr Care Pharm. 2022. 37(8):329-334.
  • Farzadeh S, Noviasky JA, Brangman SA, Yuksel JM. Impact of a clinical pharmacist telehealth service in a geriatrics assessment clinic. Sr Care Pharm. 2022. 37(7);293-303.
  • Triesel K, Seabury RW, Miller CD, Field A, Burgdorf A. Rituximab-pvvr is not an independent predictor for infusion reactions in a cohort given rituxmab-pvvr or rituximab: A single-center retrospective study. Journal of Oncology Pharmacy Practice. 2022. (Epub ahead of print)
  • Parsels KA, Seabury RW, Zyck S, Miller CD, Krishnamurthy S, Darko W, Probst LA, Latorre JG, Cwikla GM, Feldman EA. Andexanet alfa effectiveness and safety versus four-factor prothrombin complex concentrate (4F-PCC) in intracranial hemorrhage while on apixaban or rivaroxaban: A single center, retrospective, matched cohort analysis. American Journal of Emergency Medicine. 2022. (55):16-19.

  • Harris JL, DelVecchio D, Seabury SW, Miller CD, Phillips E. Pharmacists Act on Care Transitions in Stroke (PACT-Stroke): A Systems Approach. Clinical Therapeutics. 2022. Epub ahead of print).
  • Parels KA, Kufel WD, Burgess J, Seabury RW, Mahapatra R, Miller CD, Steele JM. Hospital discharge: An opportune time for antimicrobial stewardship. Ann Pharmacother. 2022. 56(8):869-877.

2021

  • Curtis Blow, Jenna Harris, Meaghan Murphy, Kelly Conn, Caitlin Toomey, Isaac Huml, Elizabeth Phillips. Evaluation of a Pharmacist – Led antibiotics stewardship program and implementation of prescribing order set. Journal of American Pharmacist Association 2021 online 26 Feb. https://doi.org/10.1016/j.japh.2021.01.030
  • Darko W, Seabury RW, Miller CD, Spinler SA, Probst LA, Cleary LM, Kelly C, Kufel WD. Implementation of a Formal Pharmacy Residency Research Certificate Program. 2021 AJHP; 78(5):436–446, https://doi.org/10.1093/ajhp/zxaa424 
  • Joelle Arieno, Robert W. Seabury, Wesley Kufel, William Darko, Christopher D Miller, William Paolo, Gregory Cwikla, Scott Riddell, and Jeffery Steele. Validation of MRSA Risk factors in Predicting MRSA Community7 Acquired Pneumonia at an Academic Medical Center. Hospital Pharmacy 2021: Hospital Pharmacy 2021. https://doi.org/10.1177/00185787211010149  
  • Kaitlyn J. Agedal, Elizabeth A. Feldman, Robert W. Seabury, William Darko, Luke A. Probst, Christopher D. Miller, and Gregory M. Cwikla. Prophylactic Enoxaparin in Critically Ill Trauma Patients: Evaluation of the Initial Dose. Hospital Pharmacy Dec 2021 DOI: 10.1177/00185787211067374  
  • Kelly CE, Miller CD, Darko W, Cwikla G, Mogle B, Featherly J, Marcinak R, Probst LA, Seabury R. A single-center cost analysis assessing a change in vasopressin formulation. AJHP. 2021. (Epub ahead of print).   
  • Kelly C, Miller C, Darko W, Cwikla G, Mogle B, Featherly J, Marcinak R, Probst LA, Seabury R. A Single-Center Cost-Analysis Assessing A Change in Vasopressin Formulation. AJHP 2021;78(13):11238-1243 https://doi.org/10.1093/ajhp/zxab153  
  • Kufel WD, Asiago-Reddy EA, Parsels KA, Sanyal S, Coyne JL. Successful treatment with secnidazole for trichomoniasis in the setting of metronidazole hypersensitivity. Int J STD AIDS. 2021. 32(13):1271-1273.
  • Kufel WD, Mastro KA, Steele JM, Wang D, Riddell SW, Paolino KM, Thomas SJ. Impact of a pharmacist-facilitated, evidenced-based bundle initiative on Staphylococcus aureus bacteremia management. 2021. 101(4). Epub ahead of print.   
  • Parsels K, Seabury R, Darko W, Probst L, Steele J. Recurrent Renal Dysfunction Secondary to Probable Piperacillin-Tazobactam-Induced Acute Interstitial Nephritis. Annals of Pharmacotherapy 2021; 55(1): 133.  
  • Parels K, Kufel W, Burgess W, Seabury RW, Mahapatra DO, Miller CD, Steele JM. Hospital Discharge: An Opportune Time for Antimicrobial Stewardship. Annals of Pharmacotherapy. 2021. (Epub ahead of print).   
  • Parsels KA, Mastro KA, Steele JM, Thomas SJ, Kufel WD. Cefiderocol: a novel siderophone cephalosporin for multidrug-resistant Gram-negative bacterial infections. J Antimicrob Chemother. 2021. 12;76(6):1379-1391.   
  • Parsels KA, Mastro K, Steele J, Thomas S, and Kufel W. A Novel Siderophore Cephalosporin for Multidrug Resistant Gram-Negative Bacterial Infections. Journal of Antimicrobial Chemotherapy.2021 Feb Published online ahead of print. PMID: 33532823DOI: 10.1093/jac/dkab015   
  • Shtoyko AN, Cwikla GM, Feldman EA, Darko W, Miller CD, Seabury, RW. Trust your gut: Effect of a pharmacist-driven pilot project to decrease alvimopan use past gastrointestinal recovery in post-surgical patients. Am J Health-System Pharm Residents Edition. AJHP May 24 2021 https://doi.org/10.1093/ajhp/zxab221• Ashley Shtoyko, Elizabeth Feldman, Gregory Cwikla, William Darko, Randall Green, Robert Seabury Use of an argatroban systemic infusion and purge solution in a patient with a percutaneous ventricular assist device with suspected HIT. AJHP August 14, 2021 https://doi.org/10.1093/ajhp/zxab331

2020 

  • Beccari VM, Seabury WR, Mogle TB, Kufel DW, Miller DC, Steele MJ. Cost comparison of AUC:MICe versus trough-based vancomycin monitoring for MRSA bacteremia. J of American Pharm Asso 2020 doi.org/10.1016/j.japh.2020.02.025.
  • Parsels K, Seabury WR, Darko W, Probst AL, Cwikla, MG, Miller DC. Is it truly ‘alpha’? Incidence of thrombotic events with andexanet alfa at a single academic medical center. Annals of Emergency medicine. 2020;75(5): 675-676 https://doi.org/10.1016/j.annemergmed.2019.12.026
  • Pegah Shakeraneh, Risako Robinson, Wesley D. Kufel, Nathan L. Tumey,  Samantha R. Benjamin,  Christopher D. Miller,  William Darko,  Luke A Probst, Robert W. Seabury. Chemical and Physical Stability of an Admixture Containing Cefepime and Vancomycin in Lactated Ringer Solution. Hospital Pharmacy 2020. doi: 1177/0018578719901278.
  • Pegah Shakeraneh, Tasaduq Fazili,  Dongliang Wang,  Jeff Steele Robert W. Seabury,  Christopher D. Miller,  William Darko,  Luke A Probst, Wesley D. Kufel. Nephrotoxicity Risk and Clinical Effectiveness of Continuous versus Intermittent Infusion Vancomycin Among Patients in an Outpatient Parenteral Antimicrobial Therapy Program. Pharmacotherapy 2020: doi:10.1002/phar.2381.
  • Scrimenti A, Probst L, Miller C, Ulen K, Noviasky J, Seabury R. Verifying Medication Orders in the Older Populations: Are we using Enough Caution? Sr Care Pharm2020;34:182 – 6.

 2019 

  • Beccari MV, Mogle BT, Sidman EF, Mastro KA, Asiago-Reddy E, Kufel WD. Ibalizumab, a Novel Monoclonal Antibody for the Management of Multidrug-Resistant HIV-1 Infection.Antimicrobial Agents and Chemotherapy. 2019;63(6). doi:10.1128/aac.00110-19.
  • Beitz ER, Robert Seabury, Christopher D. Miller, William Darko, Luke A. Probst, and Kelly E. Steidl. Clonidine for Dexmedetomidine Withdrawal in Pediatric Patients: A Single Center's Experience. The Journal of Pediatric Pharmacology and Therapeutics: 2019, Vol. 24, No. 6, pp. 542-543.
  • Blow CA, Probst LA, Miller CD, Seabury RW. Andexanet Alfa: Preferred Treatment or Therapeutic Option?.P T. 2019;44(9):533.
  • Darko W, Fancher JL, Feldman EA, Krasniak AE, Miller CD, Probst LA. Evaluating the design and conduct of teaching, education, and dissemination of knowledge learning experiences: A survey of American Society of Health System Pharmacists (ASHP)-accredited postgraduate year 1 pharmacy residency programs (TEDKLE-PGY1 survey).Journal of the American College of Clinical Pharmacy. 2019;2(5):544-553. doi:10.1002/jac5.1117.
  • Elizabeth A. Feldman, John Noviasky, Kelly R. Ulen, Christopher D. Miller, Deena Barbagallo, Robert Seabury Targeted Medication Deprescribing in the Elderly: Results of a Pharmacist-Driven Procedure in a Transitional Care Unit. Sr Care Pharm 2019;34:678 – 684.
  • Feldman EA, Meola G, Zyck S, et al. Retrospective Assessment of Desmopressin Effectiveness and Safety in Patients with Antiplatelet-Associated Intracranial Hemorrhage.Critical Care Medicine. 2019:1. doi:10.1097/ccm.0000000000004021.
  • Fovel LM, Miller CD, Seabury RW, Probst LA, Horvath L. Evaluation of Warfarin Patients with Low Time in Therapeutic Range (TTR) for Transition to Non-Vitamin-K Oral Anticoagulant (NOAC) Therapy. P T. 2019 Jun;44(6):364.
  • Fovel LM, Robert SW, Miller CD, Darko W, Probst LA, Horvath L. Safety and Efficacy of Direct Oral Anticoagulant Therapy in Patients with Cancer. Journal of Pharmacy Practice Dec 2019 online publication. doi: 10.1177/0897190019896500.
  • Krasniak A, Szymaniak G, Conn KM, Phillips E. Evaluation of clinical pharmacy priority scoring methods in an adult medicine residency clinic.Journal of the American College of Clinical Pharmacy. 2019. doi:10.1002/jac5.1110.
  • Kufel WD, Seabury RW, Mogle BT, Beccari MV, Probst LA, Steele JM. Readiness to implement vancomycin monitoring based on area under the concentration–time curve: A cross-sectional survey of a national health consortium.American Journal of Health-System Pharmacy. 2019;76(12):889-894. doi:10.1093/ajhp/zxz070.
  • Kufel WD, Eranki AP, Paolino KM, Call A, Miller CD, Mogle BT. In vivo pharmacokinetic analysis of meropenem/vaborbactam during continuous venovenous haemodialysis.Journal of Antimicrobial Chemotherapy. 2019;74(7):2117-2118. doi:10.1093/jac/dkz103.
  • Lorenzo MP, Burgess J, Darko W. Intravenous Olanzapine in a Critically Ill Patient: An Evolving Route of Administration.Hospital Pharmacy. January 2019. doi:10.1177/0018578718823484.
  • Mogle BT, Beccari MV, Steele JM, Fazili T, Kufel WD. Clinical considerations for oral beta-lactams as step-down therapy for Enterobacteriaceae bloodstream infections.Expert Opinion on Pharmacotherapy. 2019;20(8):903-907. doi:10.1080/14656566.2019.1594774.
  • Mogle BT, Baccari MV, Fazili T, Steele JM, JKufel WD. Oral antibiotics for Eneterobacteriacae bacteremia: Should betalactams be part of the conversation: Expert Opin Pharmacother 2019; Epub ahead of print.
  • Scrimenti A, Seabury RW, Miller CD, et al. Pharmacist recommendations for prophylactic enoxaparin monitoring and dose adjustment in trauma patients admitted to a surgical intensive care unit.Pharmacy Practice. 2019;17(4):1541 - 1546. doi:10.18549/pharmpract.2019.4.1541.
  • Seabury RW, Darko W, Miller CD, Steele JM, Kufel WD. Publications for Pharmacy Residents Are Challenging but Not “Nearly Unattainable Hospital Pharmacy 2019: 55(3);154 doi: 1177/0018578719882316.
  • White TR, Seabury RW, Darko W, Probst LA, Miller CD. Two High to Start? Targeting a New Starting Dose for Argatroban Infusions.Journal of Pharmacy Technology. May 2019 :875512251987269. doi:10.1177/8755122519872698.
  • Zuern A, Probst LA, Darko W, et al. Effect of a Standardized Treatment Panel on Hypoglycemic Events in Hospitalized Acute Hyperkalemic Patients Treated With Intravenous Regular Insulin.Hospital Pharmacy. April 2019. doi:10.1177/0018578719841035.

2018 

  • Fancher JL, Seabury RW, Darko W, Probst LA, Miller CD. Evaluation of a Long-Acting Opioid Restriction Policy: Does Restriction Reduce the Need for Naloxone Reversal?Hospital Pharmacy. May 2018. doi:10.1177/0018578718817471.
  • Fancher J, Meola G, Paolo W, Seabury R. Retrospective assessment of succinylcholine use in acute stroke care: What are the risks?The American Journal of Emergency Medicine. 2018;36(11):2119-2120. doi:10.1016/j.ajem.2018.03.047.
  • Feldman EA, Miller CD, Wojnowicz S, Seabury R. Significant Hyperbilirubinemia and Acute Hepatocellular Jaundice in a Pediatric Patient Receiving Deferasirox: A Case Report.The Journal of Pediatric Pharmacology and Therapeutics. 2018;23(1):64-67. doi:10.5863/1551-6776-23.1.64.
  • Kufel WD, Eranki AP, Paolino KM, Call A, Miller CD, Mogle BT. In vivo pharmacokinetic analysis of meropenem/vaborbactam during continuous venovenous haemodialysis.Journal of Antimicrobial Chemotherapy. 2019;74(7):2117-2118. doi:10.1093/jac/dkz103.
  • Mogle BT, Steele JM, Seabury RW, Dang UJ, Kufel WD. Implementation of a two-point pharmacokinetic AUC-based vancomycin therapeutic drug monitoring approach in patients with methicillin-resistant Staphylococcus aureus bacteraemia.International Journal of Antimicrobial Agents. 2018;52(6):805-810. doi:10.1016/j.ijantimicag.2018.08.024.
  • Mogle BT, Seabury RW, Jones Z, Miller CD, Steele JM. The Culture of Carbapenem Overconsumption: Where Does It Begin? Results of a Single-Center Survey.Hospital Pharmacy. 2018;54(3):175-179. doi:10.1177/0018578718775328.
  • Mogle BT, Steele JM, Thomas SJ, Bohen KH, Kufel WD. Clinical Review of Delafloxacin: A Novel Anionic fluoroquinolone. J Amtiomicrob Chemother. 2018;73(6):1439 – 1451.
  • Rose P, Cwikla G, Miller C, Probst L, Seabury R. Price-Performance Ratio Analysis Of Enteral Vitamin K Formulations. P T. 2018 Mar;43(3):168-170.
  • Stoessel AM, Hale CM, Seabury RW, Miller CD, Steele JM. The Impact of AUC-Based Monitoring on Pharmacist-Directed Vancomycin Dose Adjustments in Complicated Methicillin-Resistant Staphylococcus aureus infection.Journal of Pharmacy Practice. 2018;32(4):442-446. doi:10.1177/0897190018764564.

2017

  • Feldman EA, Miller CD, Wojnowicz S, Seabury R. Significant hyperbilirubinemia and acute hepatocellular jaundice in a pediatric patient receiving deferasirox: a case report. J Pediatr Pharmacol Ther. 2017. [Epub ahead of print].
  • Gill D, Feldman EA, Liu K. Evaluation of medication compliance for secondary prevention of acute coronary syndrome. Proc (Bayl Univ Med Cent). 2017. [Epub ahead of print].
  • Gill D, Schrader J, Kelly M, Martinez F, Syed W, Wright. Gemcitabine associated pseudocellulitis: A missed diagnosis. J Oncol Pharm Pract. 2017. [Epub ahead of print].
  • Hale CM, Steele JM, Seabury RW, Miller CD. Characterization of drug-related problems occuring in patients receiving outpatient antimicrobial therapy. J of Pharm Practice. 2017. [Epub ahead of print].
  • Krasniak A, Darko W, Miller CD, Seabury R, Probst LA. Changes in pharmacy residency training design between 2012 and 2017: A perspective of academic medical centers. Hosp Pharm. 2017. [Epub ahead of print].
  • Kufel WD, Miller CD, Johnson PR, Reid K, Zahra JJ, Seabury RW. Y-site incompatibility between premix concentrations of vancomycin and piperacillin-tazobactam: Do current compatibility testing methodologies tell the whole story? Hosp Pharm. 2017; 52(2): 132-137.
  • Kufel WD, Seabury RW, Darko W, Probst LA, Miller CD. Clinical feasibility of monitoring enoxaparin anti-Xa concentrations: Are we getting it right? Hosp Pharm. 2017;52(3):214-220.
  • Kufel WD, Seabury RW, Meola GM, Darko W, Probst LA, Miller CD. Impact of premix antimicrobial preparation and time to administration in septic patients. CJEM. 2017. [Epub ahead of print]. 
  • Lorenzo MP, MacConaghy L, Miller CD, Meola G, Probst LA, Pratt B, Steele J, Seabury RW. Impact of a combination antibiotic bag on compliance with surviving sepsis campaign goals in emergency department patients with severe sepsis and septic shock. Ann Pharmacother. 2017. [Epub ahead of print].
  • Mogle BT, Seabury RW, Jennings S, Cwikla GM. Severe neutrophilic dermatosis following submental deoxycholic acid administration. Clin Toxicol. 2017. [Epub ahead of print].
  • Probst LA, Welch TR. Pediatric drug formulations – unintended consequences of legislation. N Engl J Med. 2017; 376: 795-796.
  • Rose P, Seabury R, Cwikla G. Acutre hepatocellular juandice after dofetilide initiation: A case report. Hosp Pharm. 2017. [Epub ahead of print].
  • Seabury RW, Stoessel AM, Steel JM. Vancomycin trough concentration poorly characterizes AUC: Is it time to transition to AUC-based vancomycin monitoring? Annals of Pharmacotherapy. June, 2017. [Epub ahead of print].
  • Steele JM, Seabury RW, Hale CM, Mogle BT. Unsuccessful treatment of methicillin-resistant Staphylococcus aureus endocarditis with dalbavancin. J Clin Pharm Ther. 2017. [Epub ahead of print].

 2016

  • Hale CM, Seabury RW, Steele JM, Darko W, Miller CD. Are Vancomycin Trough Concentrations of 15-20 mg/dL Associated With Increased Attainment of an AUC/MIC ≥ 400 in Patients With Presumed MRSA Injection? Journal of Pharmacy Practice. 2016. [Epub ahead of print].
  • Kufel WD, Hale CM, Sideman EF, Orellana CE, Miller CD. Nucleoside Reverse Transcriptase Inhibitor (NRTI) Associated Macrocytosis. International Journal of Virology and AIDS. 2016; 3(18).
  • Kufel WD, Scrimenti A, Steele JM. A case of septic shock due to Serratia marcescens pyelonephritis and bacteremia in a patient receiving empagliflozin. J Pharm Pract. 2016. [Epub ahead of print].
  • Kufel WD, Zayac AS, Lehmann DF, Miller CD. Clinical application and pharmacodynamic monitoring in a patient with end-stage renal disease requiring chronic hemodialysis. Pharmacotherapy. 2016. 35(11):e166-e171
  • Phillips E, Saseen JJ. Current controversies with recent cholesterol treatment guidelines. J Pharm Pract. 2016. 29(1):15-25.
  • Sigona NS, Steele JM, Miller CD. Impact of a pharmacist-driven beta-lactam allergy interview on inpatient antimicrobial therapy: A pilot project. Journal of the American Pharmacist Association. 2016. [Epub ahead of print].
  • Stambough M, Roman M, Blair DC, Sidman EF, Miller CD. Preemptive antiretroviral therapy modifications for the management of potentially clinically significant drug interactions with direct acting hepatitis C therapies. Int J STD AIDS. 2016; 27(3):235-7.
  • Wills B, Darko W, Seabury R, Probst LA, Miller CD, Cwikla GM. Pharmacy impact on medication reconciliation in the medical intensive care unit. J of Research in Pharmacy Practice. 2016;5(2):142-5.

2015

  • Noviasky J, Darko W, Akajabor D, Makaron A, Miller C, Pierce D, Seabury R, Whalen K. Digoxin (Textbook Chapter). Casebook in Clinical Pharmacokinetics, 1st Edition. Henry Cohen, editor, McGraw Hill; 2015

2014

  • Francois D, Roberts J, Hess S, Probst L, Eksioglu Y. Medical management with diazepam for electrical status epilepticus during slow wave sleep in children. Pediatr Neurol. 2014;50(3):238-42.
  • Noviasky J, Pierce DP, Whalen K, Guharoy R, Hildreth K.  Bupivacaine Liposomal Versus Bupivacaine: Comparative Review. (Response) Hosp Pharm 2014;49(9);793-795
  • Noviasky J, Pierce DP, Whalen K, Guharoy R, Hildreth K. Bupivacaine Liposomal Versus Bupivacaine: Comparative Review. Hosp Pharm 2014;49(6):539-543
  • Patel N, Nasiri M, Koroglu A, Amin R, McGuey L, McNutt LA, Roman M, Miller CD. Prevalence of drug-drug interactions upon addition of simeprevir- or sofosbuvir-containing treatment to medication profiles of patients with HIV and hepatitis C coinfection. AIDS Res Hum Retroviruses. 2014; 372(6): 528-36.
  • Sidman E, Probst LA, Darko W, Miller CD. Evaluation of Dabigatran Utilization and Risk Among Hospitalized Patients. Ann Pharmacother. 2014; 48(3):349-53.

2013

  • Guharoy R, Noviasky J, Haydar Z, Fakih MG, Hartman C. Compounding Pharmacy Conundrum: "we cannot live without them but we cannot live with them" according to the present paradigm. Chest 2013 Apr;143:896-900 

2012

  • Noviasky J, Kelberman M. Nesiritide. Were the signals missed amid the marketing? Cardiology Today July 2012
  • Shaifali S, Karachiwala H, Noviasky J, Wong D, Elliott WC, Lehmann D. To bind or to let loose: Effectiveness of sodium polystyrene sulfonate in decreasing serum potassium. 2012 Inter J Nephrology Article ID 940320
  • Suryadevara M, Steidl KE, Probst LA, Shaw J. Inappropriate vancomycin therapeutic drug monitoring in hospitalized pediatric patients increases pediatric trauma and hospital costs. J Pediatr Pharmacol Ther. 2012; 17(2):159-65.

2010

  • Burchett DK, Darko W, Zahra J, Noviasky J, Probst L, Smith A. Mixing and compatibility guide for commonly used aerosolized medications. Am J Health Syst Pharm. 2010;67(3):227-30.
  • Steidl KE, Darko W. Probst LA, Noviasky JA, Nasser S. Rhabdomyolysis associated with phentermine. Am J Health Syst Pharm. 2010;67(22):1929-32.
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