I am a postdoctoral fellow funded by the Research Foundation of Flanders (Belgium). My current research focuses on theoretical aspects of optical imaging in cardiac electrophysiology, arrhythmogenesis during regional ischemia and stability of vortex filaments in reaction-diffusion media.

Department of Pharmacology (Weiskotten Hall- room 3160)
SUNY Upstate Medical University
750 East Adams St
Syracyse NY 13210

phone: +1-315-464-5141
fax: +1-315-464-8014
email: bernuso@upstate.edu  olivier.bernus@ugent.be

Research project

The aim of our research is to develop new methods for the study of the three-dimensional organization of cardiac arrhythmias using mathematical modeling of non-linear waves in cardiac tissue. This will help to identify the mechanisms underlying cardiac arrhythmias and fibrillation, which is of great clinical importance.

In particular we will:

1. Study the dynamics of intramural scroll waves in realistic models of cardiac tissue including accurate geometry and orthotropic anisotropy
2. Develop methods for the detection and localization of these scroll waves using optical mapping.

Our results will be compared to experimental recordings.

Recent publications

O. Bernus, C.W. Zemlin, R.F. Zaritski, S.F. Mironov and A.M. Pertsov "Alternating conduction in the ischemic border zone as a precursos of reentrant arrhythmias: a simulation study", Europace 7(S2):93-104 (2005).

O. Bernus, M. Wellner, S.F. Mironov and A.M. Pertsov "Simulation of voltage-sensitive optical signals in three-dimensional slabs of cardiac tissue: application to transillumination and coaxial scanning imaging methods", Phys. Med. Biol. 50:215-229 (2005).

O. Bernus, M. Wellner and A.M. Pertsov "Intramural wave propagation in cardiac tissue: asymptotic solutions and cusp waves", Phys. Rev. E 70:061913 (2004).

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