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Gestational Diabetic Screen (GDS)

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EPIC Test Name

1 HR GESTATIONAL GLUCOSE SCREEN

EPIC Code

LAB2586

Specimen Requirements

plasma
Minimum Volume:1 mL
Collection:Collect specimens using standard laboratory procedures.
Transport:Room Temperature ASAP
Stability:After separation,
Room Temperature: 3 days at 15-25 degrees C
Refrigerated: 72 hours at 4 degrees C
Container:GREY
Processing/Storage:Separate the sample from the cells ASAP
Rejection Causes:Hemolysis,
Insufficient Sample Volume
Notes:Draw blood one hour after patient has finished the glucose solution

Methods

Photometric assay using Hexokinase

Turnaround Time

SpecimenTurnaround TimeFrequency
plasma1 day24/7

Reference Ranges

Photometric assay using Hexokinase
All RangeUnit
<136 mg/dLmg/dL

Clinical Indications

Whom should be screened for GDM?
Based on risk facts, according to American Diabetes Association [ADA, Diabetes Care. 2007;30 (suppl 1):S4–41], for low risk women there is no need to screen and less likely to benefit from any screening, i.e., < 25 years age, not a member of ethnic group, BMI ≤ 25kg/m2, no previous history of abnormal glucose tolerance or adverse obstetrics outcomes and no known history of diabetes in first degree relatives, However, based on the study by Griffin (Diabet Med. 2000;17:26–32), there is a need for universal screening especially for women from South east Asian countries.

When to screen?
Screening is commonly performed at 24-28 weeks of gestation because insulin resistance increases during the second trimester and glucose levels rise in women who do not have the ability to produce enough insulin to adopt this resistance.

Performed

Lab
Chemistry - Community
Chemistry - Downtown

Interpretative Information

WHO 2013 diagnostic criteria:
GDM should be diagnosed at any time in pregnancy if one or more of the following abnormality are met: fasting plasma glucose 5.1 – 6.9 mmol/l (92 – 125 mg/dl), one hour plasma glucose ≥ 10.0mmol/l (180mg/dl), or 2-hour glucose 8.5 -11 mmol/l (153-199 mg/dl) after overnight fasting with 75g glucose load.

CPT

82947

LOINC

1504-0

References

World Health Organization. Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy. Geneva: World Health Organization; 2013 [Internet] Available from: http://www.who.int/diabetes/publications/Definition%20and%20diagnosis%20of% 20diabetes_new.pdf.

Contact Information

Chemistry - Downtown: (315)464-4460
Chemistry - Community: (315)492-5531
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