Molecular Diagnostic Laboratory

Shengle Zhang, MD
Shengle Zhang, MD, Director
Phone: 315 464-7131
Email: Shengle Zhang, MD

Jamie Tull, Laboratory Coordinator
Email: Jamie Tull

Kathleen Sayles
Phone: 315 464-7147
Fax: 315 464-7130
Email: saylesk@upstate.edu
Anatomic Molecular Diagnostic Laboratory

The Molecular Diagnostics Laboratory, in the Division of Anatomic Pathology at SUNY Upstate Medical University, is a Joint Commission accredited clinical diagnostic facility which offers a growing menu of molecular testing on solid tumors. The laboratory is currently the only laboratory with NYS approval for a variety of molecular tests. The laboratory performs PCR and FISH for adult and pediatric neoplasms including various soft tissue tumors, carcinomas and brain tumors. In addition to serving the Upstate Medical University community we are also a referral laboratory for other hospitals and clinics.

To order lab supplies, or for lab results, call client services at 315 464-7147 or fax a request to 315 464-7130.

Submitting a Sample

  1. Choose appropriate test(s) from roster of tests available
  2. Fill out the requisition form PDF document
  3. Include blocks of formalin fixed paraffin embedded tissue and a copy of the Surgical Pathology report

Shipping & Handling Information

CLIA # 33D0654590

Specimen Shipping Information

  1. Notify the laboratory in advance of specimen arrival and/or to arrange for specimen pickup (pre-arranged courier pick up available in certain areas) by calling 315 464-7147, 315 464-7134 or Fax 315 464-7130
  2. The transport of specimens by overnight express courier service is preferred

Specimen Shipping Address

Upstate Medical University
Dept. of Pathology
UH6803 750 East Adams St.
Syracuse, NY 13210
Attn: Kathleen Sayles

Supplies

To request supplies and prepaid courier air bills call 315 464-7147, Monday – Friday, 8:00 am – 4:30 pm.

Tests Available

HER2 by FISH

Test Includes: HER2 Gene Amplification by FISH
Indications: Breast cancer to determine prognosis and predict response to therapy
Sample Requirements: Formalin-fixed, paraffin embedded tissue with the invasive tumor component. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee: $567.00

1p/19q Deletion by FISH

Test Includes: 1p/19q Deletion by FISH
Indications: Oligodendroglioma, to determine prognosis and predict response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

SS18(SYT) Break Apart by FISH

Test Includes: SS18(SYT) Gene Break Apart by FISH
Indications: Synovial sarcoma to facilitate diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

EWS Break Apart by FISH

Test Includes: EWS gene break apart by FISH
Indications: Ewings sarcoma, DSRCT (Desmoplastic small round cell tumor), Clear cell carcinoma, Extraskeletal myxoid chondrosarcoma, Myxoid/round cell liposarcoma to facilitate diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor . Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

FOXO1(FFKHR) Gene Break Apart by FISH

Test Includes: FOXO1(FKHR) Gene Break Apart by FISH
Indications: Alveolar rhabdomyosarcoma to facilitate diagnosis
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements:
Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time:
Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

EGFR Gene Amplification by FISH

Test Includes: EGFR Gene Amplification by FISH
Indications: Lung cancer, colon cancer, glioblastoma, and response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Thursday and Friday.
CPT Code: 88365
Fee $567.00

DDIT3 (CHOP) Gene Break Apart by FISH

Test Includes: DDIT3(CHOP) Gene Break Apart by FISH
Indications: Myxoid/Round Cell Liposarcoma diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

therascreen EGFR Gene Mutation by PCR 

Test Includes: therascreen EGFR Gene Mutation by PCR
Indications: Lung Adenocarcinoma predication of prognosis and response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 81235, 88381
Fee $586.00

KRAS Gene Mutation Analysis by therascreen real-time PCR or DNA Sequencing

Test Includes: KRAS Gene Mutation Analysis by therascreen real-time PCR or DNA Sequencing
Indications: Colon or lung adenocarcinoma, prediction of response to therapy.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 81275,88381
Fee $858.00

IGH-CCND1 Gene Fusion by FISH 

Test Includes: IGH-CCND1 Gene Fusion by FISH
Indications: Mantle Cell Lymphoma Diagnosis.
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

BRAF(V600E) Mutation Analysis by PCR

Test Includes: BRAF(V600E) Mutation Analysis by PCR
Indications: Lung, colon, and thyroid carcinoma diagnosis
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 81210
Fee $640.00

ALK Gene Rearrangement by FISH

Test Includes: ALK Gene Rearrangement by FISH
Indications: Lung cancer predication of response to therapy
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00

ROS1 Gene Rearrangement by FISH

Test Includes: ROS1 Gene Rearrangement by FISH
Indications: Lung adenocarcinoma prediction of response to therapy
Sample Requirements: Formalin-fixed, paraffin embedded tissue containing tumor. Include a copy of the Pathology Report.
Shipping Requirements: Transport at room temperature. Send by overnight courier with a completed requisition form PDF document
For help with this form contact:
Kathleen Sayles
315 464-7147
saylesk@upstate.edu
Turnaround Time: Test performed on Tuesday and Thursday. Results available on Wednesday and Friday.
CPT Code: 88365
Fee $567.00