Faculty Research

Shengle Zhang, M.D.

Assistant Professor, Pathology
2319 Weiskotten Hall
Upstate Medical University
750 East Adams Street
Syracuse, NY 13210
315-464-4750

Lab/Professional Web Site

Education and Clinical Training

M.D.: 1982, Wannan Medical College, China, Medicine
MS: 1985, Shangdong Academy of Medical Sciences, Biochemistry
Residency: Anatomic and Clinical Pathology, 2001, Saint Barnabas Health Care System, New Jersey
Fellowship: Surgical Pathology, 2002, Roswell Park Cancer Center, New York
Fellowship: Molecular Pathology/Molecular Diagnostics, 2004, Johns Hopkins Medical Institutions, Maryland.

Clinical Specialty

Anatomic and Clinical Pathology, Certified: 2002
Molecular Pathology

Clinical Department/Section Affiliations

Pathology/Anatomic Pathology

Clinical Interests

Oncologic Pathology and Molecular Diagnostics.

Research Program and Department Affiliations

Pathology

Research Interests

Molecular Oncology and its clinical application.

Research Abstract

Recent Selected References:

1. Shah SS, Wang Y, Tull J, and Zhang S. Effect of high copy number of HER2 associated with polysomy 17 on HER2 protein expression in invasive breast carcinoma. Diagnostic Molecular Pathology. 18:30-33, 2009.

2. Mehra S, de la Roza G, Tull J, Shrimpton A, Valente A, Zhang S. Detection of FKHR gene break-apart by fluorescence in situ hybridization (FISH) in formalin fixed paraffin embedded alveolar rhabdomyosarcomas and its clinicopathological correlation. Diagnostic Molecular Pathology. 17(1):14-20, 2008.

3. El-Zammar, O, Zhang, S, Katzenstein, ALA. Comparison of FISH, PCR, and IHC techniques in assessing EGFR genetic alterations and protein expression in lung adenocarcinoma: Relationship to clinicopathologic features. Mod Pathol 20(2S):320A, 2007.

4. Nasr, MR, Mukhopadhyay S, Zhang S and Katzenstein A-L: Immunohistochemical markers in diagnosis of papillary throid carcinoma: utility of HBME1 combined with CK19 immunostaining. Modern Pathology, 19:1631-1637, 2006.

5. Kathleen M. Murphy, Shengle Zhang, Tanya Geiger, Michael J. Hafez, Jeff Bacher, Karin D. Berg,and James R. Eshleman, Comparison of the Microsatellite Instability Analysis System and the Bethesda Panel for the Determination of Microsatellite Instability in Colorectal Cancers. Journal of Molecular Diagnostics 8:305-311, 2006.

6. Montgomery E, Mamelak AJ, Gibson M, Maitra A, Sheikh S, Amr SS, Yang S, Brock M, Forastiere A, Zhang S, Murphy K, Berg K. Overexpression of Claudin Proteins in Esophageal Adenocarcinoma and its Precursor Lesion. Applied Immunohistochem Mol Morphol. 14:1, 2006.

7. Zhang S, Hawkins AL and Griffin, CA: Immuno-FISH assay for plasma cell dyscrasias. Journal of Molecular Diagnostics. 5:269A, 2003.

8. Zhang S, Murphy KM, Maitra A, Montgomery E, and Berg KD: Identification of claudins 3, 4 and 7 overexpression in gastric adenocarcinoma by global gene expression analysis and immunohistochemical validation. Journal of Molecular Diagnostics 5:282A, 2003.

9. Zhang S, Murphy K, Borowitz M and Berg K: IgVH somatic mutation identification in chronic lymphocytic leukemia (CLL). Journal of Molecular Diagnostics. 4:244A, 2002.

10. Zhang S, Ashraf M and Schinella R: Ischemic colitis with atypical reactive changes mimicking dysplastia (pseudodysplasia). Arch Path Lab Med, 125:224-227, 2001.

11. Zhang S and Schinella R: Expression of ER, PR, Her2/neu and Ki-67 and their correlation in 55 cases of infiltrating ductal carcinoma of the breast. J Tumor Marker Oncol, 15:123-127, 2000.

12. Zhang S, Zhang HS, Cordon-Cardo C, Ragupathi G, Livingston PO: Selection of tumor antigens as targets for immune attack using immunohistochemistry : protein antigens. Clin Cancer Res 4:2669-76, 1998.

This profile was last updated on 05/19/2009

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