Center for Humanized SCID Mouse Models

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SUNY Upstate Medical University currently maintains a severe combined immunodeficiency (SCID) mouse facility which has been successfully used to develop human xenograft models for the testing of chemotherapeutic and immunomodulatory therapeutics.

The goal of the faculty in this highly specialized research unit is to better understand disease pathogenesis and to develop preclinical models to test novel anti-virals, vaccines and chemotherapeutic drugs. Combined with state-of-the-art imaging capabilities, we are able to visualize virus replication and cancer responses to chemotherapy in whole animals using the IVIS technology.