Research Faculty

Kan Liu, MD, PhD

Kan Liu, MD, PhD
Appointed 09/21/09
Women's Health Network
5TH FL Upstate Health Care Center
90 Presidential Plaza
Syracuse, NY 13202

315 464-4536

Current Appointments

Hospital Campus

  • Downtown
  • Community

Clinical Section Affiliations

  • Medicine: Cardiology
  • Medicine - Community Campus: Cardiology
  • Upstate Heart and Vascular Center: Cardiology

Research Programs and Affiliations

  • Medicine


Education & Fellowships

  • Fellowship: Washington University at St. Louis, 2009, Cardiology
  • Residency: University of Texas Medical Branch Hospitals, 2006, Internal Medicine
  • Additional Training: University of Alabama at Birmingham, 2003, Research Assistant Professor
  • Additional Training: University of Alabama at Birmingham, 2002, Instructor, Internal Medicine
  • PhD: University of Alabama at Birmingham, 2001, Internal Medicine and Cellular Biology
  • MD: Sun Yat-Sen University of Medical Sciences, 1992

Clinical Interests

  • -Cardiology consult
    -Invasive cardiology and cardiovascular imaging,
    -Coronary artery disease prevention.

Research Interests

  • -Endothelial dysfunction in coronary artery disease.
    -Lipotoxicity/glucotoxicity and endothelial/myocyte dysfunction in diabetes.
    -Clinical and genetic analysis of valve diseases/Strain/strain rate imagine in cardiomyopathy.

Clinical Trials

  • Effect of Bariatric surgery on Ventricular Repolarization
    Read more

Specialties & Certification

  • Internal Medicine
  • Cardiology
  • Cardiovascular Computed Tomography
  • Echocardiography
  • Nuclear Cardiology
  • Cardiovascular MRI

Diseases & Conditions Treated

  • Abdominal Aortic Aneurysm (AAA)
  • Angina
  • Aortic Aneurysm
  • Aortic Valve Regurgitation
  • Arrhythmias
  • Ascending Aortic Aneurysm
  • Atherosclerosis
  • Atrial Fibrillation
  • Atrial Septal Defect (ASD)
  • Blood Clots
  • Cardiac Arrest
  • Cardiomyopathy
  • Carotid Artery Aneurysm
  • Heart Disease
  • Heart Disease and Women
  • Heart Failure
  • Heart Infection
  • Heart Murmur
  • Heart Palpitations
  • Heart Valve Disease
  • Heat Illness
  • Murmers
  • Myocarditis
  • Syncope


  • Adults


  • Angiogenesis
  • Angiography
  • Aortic Dissection Treatment
  • C-Reactive Protein Testing
  • Calcium-Score Screening Heart Scan
  • Cardiac Catheterization
  • Cardiac Computed Tomography
  • Cardiovascular MRI
  • Cardioversion
  • Chest Pain Treatment
  • Chest X-Ray - Heart
  • Echocardiography
  • Exercise Stress Echocardiogram
  • Exercise Stress Test
  • Heart Nuclear Imaging
  • Heart Nuclear Stress Testing
  • Heart Ultrasounds
  • Non-Invasive Testing for Vascular Disease
  • Nuclear Adenosine Stress Test
  • Nuclear Exercise Stress Test
  • Nuclear Imaging
  • Women's Health


  • American Heart Association (AHA)
  • Society of Cardiovascular CT (SCCT)
  • American College of Physicians (ACP)
  • American Society of Echocardiography (ASE)
  • Society of Cardiovascular MRI (SCMR)
  • American College of Cardiology (ACC)

Current Hospital Privileges

  • Upstate University Hospital
  • Crouse Hospital
  • VA Medical Center

Languages Spoken (Other Than English)

  • Chinese


Link to PubMed External Icon (Opens new window. Close the PubMed window to return to this page.)


Selected Publications

Sun ZX, Singh P, Wei TM, Kozman H, Liu K. Is the Heart Really Stressed Out of Energy? J Am Coll Cardiol: Cardiovasc Imaging. 2015 (in press).

Lei J, Dhamoon AS, Wang JF, Iannuzzi M, Liu K. Walking the Tightrope: Using Quantitative Doppler  Echocardiography to Optimize Ventricular Filling Pressures in Patients Hospitalized for Acute Heart Failure. European Heart Journal: Acute Cardiovascular Care. 2015 (in press).

Liu K, Krone JK.  What Truly Causes the Adverse Outcome of Tako-Tsubo Cardiomyopathy? J Am Coll Cardiol: Cardiovasc Imaging. 2014, 7(7):742-743.

Dhamoon A, Liu K.  How can we improve inpatient management of heart failure? J Am Coll Cardiol: Heart Failure. 2014, 2:199-200

Liu K, Ronald K. Evaluation of Coronary Steal in Myocardium Supplied by Coronary Collaterals: The Role of Speckle Tracking Analysis in Resting and Stress Echocardiography. Echocardiography, 2013, 30:1111-1117

Boppana S, Bhatta L, Liu K.  Reversible Tricuspid Regurgitation in Acute and Chronic Cardiomyopathies: Medical Management vs. Surgical Intervention? J Am Coll Cardiol: Cardiovasc Imaging. 2013,6:920-921.

Liu K, Carhart R. Reverse McConnell's sign: a unique right ventricular feature of Takotsubo cardiomyopathy. Am J Cardiol.  2013, 11: 1232-1235.

Tian J, Wang J, Li Y, Villarreal D, Carhart R, Dong Y, Wen Y, Liu K.  Endothelial Function in Patients With Newly Diagnosed Type 2 Diabetes Receiving Early Intensive Insulin Therapy. Am J Hypertens.  2012, 25(12):1242-1248.

Tian J Wen YL, Yan Li, Cheng H, Yang HY,  Wang JF, Kozman H, Villarreal D, Liu K.. Vascular endothelial dysfunction in patients with newly diagnosed type 2 diabetes and effects of 2-year and 5-year multi-factorial intervention. Echocardiography, 2011, 28 (10): 1133-1140.

Dhakal P, Liu K, Kozman H. Beta receptor antagonist cessation resulted in Tako- tsubocardiomyopathy in a male quadriplegic patient. Mayo Clin Proc 2011, 86(2):168.

Liu K, Paterson AJ, Zhang F, et al. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism.J Neurochem. 2004 May;89(4):1044-1055.

Liu K, Paterson AJ, Konrad RJ, et al. Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion. Mol Cell Endocrinol. 2002 Aug 30;194(1-2):135-146.

Liu K, Paterson AJ, Chin E, et al. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death. Proc Natl Acad Sci U S A. 2000, 97(6):2820-2825.

Liu K, Ou J, Saku K, et al. Efficient nuclear delivery of antisense oligodeoxynucleotides and selective inhibition of CETP expression by apo E peptide in a human CETP-stably transfected CHO cell line. Arterioscler Thromb Vasc Biol. 1999, 19:2207-2213.

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