Kan Liu, MD, PhD
CURRENT APPOINTMENTS
SPECIALTIES
LANGUAGES
PATIENT TYPE
RESEARCH PROGRAMS AND AFFILIATIONS
RESEARCH INTERESTS
- Endothelial dysfunction in coronary artery disease
- Lipotoxicity/glucotoxicity and endothelial/myocyte dysfunction in diabetes
- Clinical and genetic analysis of valve diseases/Strain/strain rate imagine in cardiomyopathy
ASSOCIATIONS / MEMBERSHIPS
EDUCATION
RESEARCH ABSTRACT
Selected Publications
Sun ZX, Singh P, Wei TM, Kozman H, Liu K. Is the Heart Really Stressed Out of Energy? J Am Coll Cardiol: Cardiovasc Imaging. 2015 (in press).
Lei J, Dhamoon AS, Wang JF, Iannuzzi M, Liu K. Walking the Tightrope: Using Quantitative Doppler Echocardiography to Optimize Ventricular Filling Pressures in Patients Hospitalized for Acute Heart Failure. European Heart Journal: Acute Cardiovascular Care. 2015 (in press).
Liu K, Krone JK. What Truly Causes the Adverse Outcome of Tako-Tsubo Cardiomyopathy? J Am Coll Cardiol: Cardiovasc Imaging. 2014, 7(7):742-743.
Dhamoon A, Liu K. How can we improve inpatient management of heart failure? J Am Coll Cardiol: Heart Failure. 2014, 2:199-200
Liu K, Ronald K. Evaluation of Coronary Steal in Myocardium Supplied by Coronary Collaterals: The Role of Speckle Tracking Analysis in Resting and Stress Echocardiography. Echocardiography, 2013, 30:1111-1117
Boppana S, Bhatta L, Liu K. Reversible Tricuspid Regurgitation in Acute and Chronic Cardiomyopathies: Medical Management vs. Surgical Intervention? J Am Coll Cardiol: Cardiovasc Imaging. 2013,6:920-921.
Liu K, Carhart R. Reverse McConnell's sign: a unique right ventricular feature of Takotsubo cardiomyopathy. Am J Cardiol. 2013, 11: 1232-1235.
Tian J, Wang J, Li Y, Villarreal D, Carhart R, Dong Y, Wen Y, Liu K. Endothelial Function in Patients With Newly Diagnosed Type 2 Diabetes Receiving Early Intensive Insulin Therapy. Am J Hypertens. 2012, 25(12):1242-1248.
Tian J Wen YL, Yan Li, Cheng H, Yang HY, Wang JF, Kozman H, Villarreal D, Liu K.. Vascular endothelial dysfunction in patients with newly diagnosed type 2 diabetes and effects of 2-year and 5-year multi-factorial intervention. Echocardiography, 2011, 28 (10): 1133-1140.
Dhakal P, Liu K, Kozman H. Beta receptor antagonist cessation resulted in Tako- tsubocardiomyopathy in a male quadriplegic patient. Mayo Clin Proc 2011, 86(2):168.
Liu K, Paterson AJ, Zhang F, et al. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism.J Neurochem. 2004 May;89(4):1044-1055.
Liu K, Paterson AJ, Konrad RJ, et al. Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion. Mol Cell Endocrinol. 2002 Aug 30;194(1-2):135-146.
Liu K, Paterson AJ, Chin E, et al. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death. Proc Natl Acad Sci U S A. 2000, 97(6):2820-2825.
Liu K, Ou J, Saku K, et al. Efficient nuclear delivery of antisense oligodeoxynucleotides and selective inhibition of CETP expression by apo E peptide in a human CETP-stably transfected CHO cell line. Arterioscler Thromb Vasc Biol. 1999, 19:2207-2213.