Students Profiles
Return to student list
|
|
David Lubin
Ph.D. (5th year)
lubind@upstate.edu
Department: Biochemistry and Molecular Biology
Advisor: Stewart Loh, Ph.D.
|
Research Interests:
I work in the area of protein folding/dynamics as relating to the structure and function of p53, the human tumor suppressor. A common genetic change in cancer is through mutation of p53, specifically "hotspot" regions which I study using a variety of structural and functional assays. We seek to understand the mechanism for inactivation of full-length p53 and try to understand how small molecule therapies could be developed to rescue p53 in tumors.
| 
