Student Publications in 2005-2008

Bruns MB, Miller MW. Neurotrophin ligand-receptor systems in somatosensory cortex of adult rat are affected by repeated episodes of ethanol. Exp Neurol. Apr;204(2):680-92, 2007.

Bruns MB, Miller MW. Functional nerve growth factor and trkA autocrine/paracrine circuits in adult rat cortex are revealed by episodic ethanol exposure and withdrawal. J Neurochem. Mar;100(5):1155-68, 2007.

Christophi GP, Hudson CA, Gruber RC, Massa PT. Promoter-Specific Induction of the Phosphatase SHP-1 by Viral Infection and Cytokines in CNS Glia. Journal of Neurochemistry (2008) March 10 [Epub ahead of print].

Scarisbrick IA, Blaber SI, Tingling JT, Rodriguez M, Blaber M, Christophi GP. Potential scope of action of tissue kallikreins in CNS immune-mediated disease. Journal of Neuroimmunology. 178(1-2):167-76, 2006.

Priori SG, Pandit SV, Rivolta I, Berenfeld O, Ronchetti E, Dhamoon A, Napolitano C, Anumonwo J, di Barletta MR, Gudapakkam S, Bosi G, Stramba-Badiale M, Jalife J. A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene. Cir Res96: 800-807, 2005.

Dhamoon AS , Jalife J. The inward rectifier current (I K1) controls cardiac excitability and is involved in arrhythmogenesis.Heart Rhythm2:316-324, 2005.

Antshel KM, Fremont W, Roizen N, Dhamoon A, Kates W. ADHD and simple phobias are prevalent psychiatric conditions in youth with velocardiofacial syndrome (VCFS). J Am Acad Child Adolesc Psychiatry45:596-603, 2006.

Dubroff JG, Stevens RT, Hitt J, Maier DL, McCasland JS, Hodge CJ. Use-dependent plasticity in barrel cortex: intrinsic signal imaging reveals functional expansion of spared whisker representation into adjacent deprived columns. Somatosens Mot Res 22:25-35, 2005.

Dubroff JG, Stevens RT, Hitt J, Hodge CJ Jr, McCasland JS. Anomalous functional organization of barrel cortex in GAP-43 deficient mice. Neuroimage 29:1040-1048, 2006.

Nagy G, Ward J, Mosser, DD, Koncz, A, Gergely P JR, Stancato C, Oian Y, Fernandez, D, Niland,B, Grossman CE, Telarico, T, Banki K, Perl A. Regulation of CD4 expression via recycling by HRES-1RAB4 controls susceptibility to HIV infection. J Biol Chem 281:34574-34591, 2006.

Nagy, G., Koncz, A., Fernandez, D. and Perl A. Nitric oxide, mitochondrial hyperpolarization, and T-cell activation. Free Radic. Biol. Med. 42: 1625-1631, 2007.

Fernandez, D., Bonilla, Phillips, P.E. and Perl, A. Signaling abnormalities in systemic lupus erythematosus as potential drug targets. Endocrin, Metabolic & Immune Disorders - Drug Targets. 6: 305-311, 2006.

Perl, A., Nagy, G.,  Koncz, A., Gergely, P., Fernandez, D., Doherty, E., Telarico, T., Bonilla, E. and Phillips, P.E. (2008) Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE. Autoimmunity, in press.

Fernandez D, Bonilla E, Mirza, N, Niland B, Perl A. Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus. Arthritis Rheum. 54(9):2983-8. 2006.

Gerber AM, Vallano ML. Structural properties of the NMDA receptor and the design of neuroprotective therapies. Mini-Rev Med Chem 6:805-815, 2006.

Griffith C, Noonan S, Lou E, Shillitoe EJ.  An oncolytic mutant of Herpes simplex virus Type-1 in which replication is governed by a promoter/enhancer of Human papillomavirus Type-16.  Cancer Gene Therapy.  Dec;14(12): 985-993, 2007.

Hudson CA, Christophi GP, Cao L, Gruber RC, Massa PT. Regulation of avoidant behaviors and pain by the anti-inflammatory tyrosine phosphatase SHP-1. Neuron Glia Biology. 2:235-246, 2006.

Hudson CA, Modal TK, Cao L, Kasten-Jolly J, Huber VC, Lawrence DA. The dietary supplement ephedrine induces Beta-adrenergic mediated exacerbation of systemic lupus erythematosus in NZM391 mice. Lupus 14:293-307, 2005.

Bonaparte KL, Hudson CA, Wu C, Massa PT. Inverse regulation of inducible nitric oxide synthase (iNOS) and arginase I by the protein tyrosine phosphatase SHP-1 in CNS glia. Glia 53:827-835, 2006.

Kelley, GG, Kaproth-Joslin, KA, Reks, SE, Smcrka AV, Wojcikiewicz RJ. G-protein-coupled receptor agonists activate endogenous phospholipase C epsilon and phospholipase C B3 in a temporally distinct manner. J Biol Chem. 281(5):2639-48, 2006.

Oestreich EA, Wang H, Malik S, Kaproth-Joslin KA, Blaxall BC, Kelley GG, Dirksen RT, Smrcka AV.  Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes.  J. Biol Chem 282(8):5488-95, 2007.

Mercer SE, Ewton DZ, Deng, X, Lim S, Mazur T, Friedman E. Myrk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts. J Biol Chem 280:25788-25801, 2005.

Mercer SE, Friedman, E. Mirk/Dyrk1B: A multifunctional dual-specificity kinase involved in growth control, differentiation and cell survival. Cell Biochem Biophys 45:303-315, 2006.

Mercer SE, Ewton, D, Shah S, Mazur T, Naqvi A, Friedman E. Mirk/Dyrk1B mediates survival in rhabdomyosarcoma. Cancer Res 66:5143-5150, 2006.

Burleson ML, Mercer SE, Wilk-Blaszczak MA. Isolation and characterization of a putative O(2) receptor from the gills of the channel catfish (Ictalurus punctatus). Brain Res 1092:100-107, 2006.

Deng X, Ewton DZ, Li S, Naqvi A, Mercer SE, Landas S, Friedman E. The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma. Cancer Res 66:4149-4158, 2006.

Jin K, Lim S, Mercer SE, Friedman E. The survival kinase Mirk/Dyrk1B is activated through Rac1-MKK3 signaling. J Biol Chem 280:42097-42105, 2006.

Monaco EA III, Vallano ML. Role of protein kinases in neurodegenerative disease: cyclin-dependent kinases in Alzheimer’s disease. Front Biosci 10:143-159, 2005.

Monaco EA III, Vallano ML. Roscovitine triggers excitotoxicity in cultured granule neurons by enhancing glutamate release. Mol Pharmacol 68:1331-1342, 2005.

Ohira M., Smardon AM, Charsky CM, Liu J, Tarsio M, Kane PM. The E and G subunits of the yeast V-ATPase interact tightly and are both present at more than one copy per V1 complex. J Biol Chem. 281(32):22752-60, 2006.

Tripp A, Banerjee P, Sieburg M, Planelles V, Li F, and Feuer G. Induction of Cell Cycle Arrest by Human T-Cell Lymphotropic Virus Type 1 Tax in Hematopoietic Progenitor (CD34+) Cells: Modulation of p21cip1/waf1 and p27kip1 Expression. J Virology 79: 14069-14078, 2005.

Tyler MJ, Cameron DA. Cellular pattern formation during retinal regeneration: a role for homotypic control of cell fate acquisition. Vision Res. 47(4):501-11. 2007.

Reali F, Spivey MJ, Tyler MJ, Terranova J. Inefficient conjunction search made efficient by concurrent spoken delivery of target identity. Perception and Psychophys. 68(6):959-74 2006.

Tyler M, Carney LH, Cameron DA. Control of cellular pattern formation in the vertebrate retina by homotypic regulation of cell fate decisions. J Neurosci 25:4565-4576, 2005.

Ward J., Bonaparte M., Sacks J., Guterman J., Fogli M., Mavilio D. and Barker E. HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Blood 110(4):1207-14, 2007.

Wu W, Rochford R, Toomey L, Harrington W Jr, Feuer G. Inhibition of HHV-8/KSHV infected primary effusion lymphomas in NOD/SCID mice by azidothymidine and interferon-alpha. Leuk Res 29:545-555, 2005. 

Wu W, Vieira J, Fiore N, Banerjee P, Sieburg M, Rochford R, Harrington Jr W, Feuer G. KSHV/HHV-8 infection of human hematopoietic progenitor (CD34+) cells: persistence of infection during hematopoiesis in vitro and in vivo. Blood 108(1): 141-51, 2006.

Zapata HJ, Nakatsagawa M, Moffat JF. Varicella-zoster virus infection of human fibroblast cells activates the c-Jun N-terminal kinase pathway. J Virol. Jan;81(2):977-90, 2007.