Constance K Stein, PhD

Current Appointments

• Professor of Pathology
• Director of Cytogenetics
• Associate Director of Molecular Diagnostics

Hospital Campus

• Downtown

Education & Fellowships

• Fellowship: University of Michigan Hospitals and Health Centers, 1989, Medical Genetics/ Cytogenetics/Molecular Diagnostics
• PhD: University of Michigan, 1984, Biological Sciences
• MS: University of Michigan, 1978, Zoology
• BA: University of California at Riverside, 1973, Biology

Specialties & Certification

• Cytogenetics
• Molecular Genetics

Diseases & Conditions Treated

• Genetic Conditions

Treats

• Adults and Children

Treatments/Services

• Genetic Testing
• Laboratory Services

Associations/Memberships

• American Society of Human Genetics (ASHG)
• American College of Medical Genetics (ACMG)
• Association of Genetic Technologists
• Association of Molecular Pathology (AMP)

Current Hospital Privileges

• Upstate University Hospital

Research Abstract

Selected Bibliography

Riccardi, G. F; C. K. Stein, G.de la Roza, T. A. Damron.  2010.  Newly described translocation, t(18;19)(q23;q13.3) in abdominal wall soft tissue tumor resembling Ewing sarcoma/Peripheral Neuroectodermal Tumor. (accepted:  Genes Chromosomes and Cancer).

Stein, C. K. and Hoo, J. J.  2007. "Zwilling" versus "Tai Chi" Configuration of a Double-Sized Ring Chromosome.  Amer. J. Med. Genet. 143A(8): 903-905.

Coyle, T. E.; A. K. Bair, C. K. Stein, N. Vajpayee, S. Mehdi, J. Wright.  2005.  Acute leukemia associated with valproic acid treatment:  A novel mechanism for leukemogenesis?  Am. J. Hematol. 78: 256-260.

Shrimpton, A. E.; B. R. Braddock, L. L. Thomson, C. K. Stein, and J. J. Hoo.  2004.  Molecular delineation of deletions on 2q37.3 in three cases with an Albright hereditary osteodystrophy-like phenotype.  Clin. Genet. 66: 537-544.

Stein, C. K.; T. W. Glover, J. L. Palmer, and B. L. Glisson. 2002. Direct correlation between FRA3B expression and cigarette smoking. Genes, Chromosomes and Cancer 34:333-340.

Bellinger, M.; K. Yung, R. Grimshaw, M. Muscolino, M. Aistars, and C. K. Stein. 2002. 4-Way translocations detected as a result of reproductive errors. Appl. Cytogenet. Presented at the 27th AGT annual meeting, Cincinnati, AZ.

Stein, C. K. 2000. Applications of Cytogenetics in Modern Pathology. In Clinical Diagnosis and Management by Laboratory Methods, 20th Edition, J. B. Henry, ed., Chapter 62. Philadelphia, WB Saunders Co.

Stein, C. K. 1999. Modified G-11 staining protocol for human and hybrid cells. Somat. Cell Molec. Genet. 24: 191-195.

Friedman, H. D.; S. O. Sanderson, C. K. Stein, A. Shrimpton, N. J. Gonchoroff, K. W. Zamkoff, and T. P. Loughran. 1998. Extramedullary granulocytopoiesis mimicking recurrent lymphoma after prolonged administration of human recombinant granulocyte-colony stimulating factor. Ann. Hematol. 77: 79-83.

Ortigas, A. P.; C. K. Stein, L. L. Thomson, and J. J. Hoo. 1997. Delineation of 14q32.3 deletion syndrome. J. Med. Genet. 34: 515-517.

Stein, C. K.; S. E. Stred, L. L. Thomson, F. C. Smith, and J. J. Hoo. 1996. Interstitial 6q deletion and Prader-Willi like phenotype. Clin. Genet. 49: 306-310.

Friedman, H. D.; R. E. Hutchison, J. R. Smith, N. J. Gonchoroff, C. K. Stein, and B. J. Poiesz. 1994. CD8+ polylobated T-cell leukemia/lymphoma: A case report with immunophenotypic, ultrastructural, gene rearrangement, karyotypic, and DNA content analysis and autopsy description. Arch. Pathol. Lab. Med. 118: 722-727.

Glover, T. W.; C. K. Stein, E. Legius, L. Anderson, A. Brereton, and S. Johnson. 1991. Molecular and cytogenetic analysis of tumors in von Recklinghausen neurofibromatosis. Genes Chrom. Cancer 3: 62-70.

Gorski, J. L.; E. N. Burright, C. Harnden, C. K. Stein, T. W. Glover, and E. Reyner. 1991. Localization of DNA sequences to a region within Xp11.21 between incontinentia pigmenti (IP1) X-chromosomal translocation breakpoints. Am. J. Hum. Genet. 48: 53-64.

Gribbin, T. E.; C. K. Stein, J. S. Harrison, T. W. Glover, C. A. Hanson, J. J. Wasmuth, R. L. Cody, and B. S. Mitchell. 1989. Association of a mature B cell leukemia with a 4p+ chromosomal abnormality: Derivation and characterization of a cell line. Leukemia 3: 643-647.

Glover, T. W. and C. K. Stein. 1988. Chromosome breakage and recombination at fragile sites. Amer. J. Hum. Genet. 43:265-273.

Glover, T. W. and C. K. Stein. 1987. Induction of sister chromatid exchanges at common fragile sites. Amer. J. Hum. Genet. 41:882-890.