Student Publications

2012

• Jie An et al. CHCM1/CHCHD6, a novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. J Biol Chem, in press. [Epub ahead of print] PMID: 22228767
• Mehdi Najafi et al. Steric volume exclusion sets soluble protein concentrations in photoreceptor sensory cilia. Proc Natl Acad Sci 109(1):203-8 (2012).

2011

• David Auerbach et al. Structural heterogeneity promotes triggered activity, reflection and arrhythmogenesis in cardiomyocyte monolayers. J. Physiol. 589(Pt 9)2363-81 (2011).
• Rene Choi et al. Cone degeneration following rod ablation in a reversible model of retinal degeneration. Invest Ophthalmol Vis Sci. 52(1):364-73 (2011).
• George Christophi et al. Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-beta 1a treated multiple sclerosis patients. 307(1-2):41-5 (2011).
• Steven Hicks and Michael Miller. Effects of ethanol on transforming growth factor beta1-dependent and -independent mechanisms of neural stem cell apoptosis. Exp Neurol. 229(2):372-80 (2011).
• Jason Horton et al. Physeal bystander effects in rhabdomyosarcoma radiotherapy: experiments in a new xenograft model. Sarcoma. 2011:815190 (2011).
• Lingyan Jiang et al. Cullin-4A-DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis. J Biol Chem. 286(9):6971-8 (2011).
• Adem Koksal and Gino Cingolani. Dimerization of Vaccinia virus VH1 is essential for dephosphorylation of STAT1 at tyrosine 701. J Biol Chem. 286(16):14373-82 (2011).
• Kaylen Lott et al. A minimal NLS in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin {alpha}1. J Biol Chem., in press.
• Justine P. Lu et al. RNF170 Protein, an Endoplasmic Reticulum Membrane Ubiquitin Ligase, Mediates Inositol 1,4,5-Trisphosphate Receptor Ubiquitination and Degradation. The Journal of Biological Chemistry 286:24426-24433 (2011).
• Sam J. Mackenzie et al. Cauda Equina Repair in the Rat: Part 2. Time Course of Ventral Root Conduction Failure. J. Neurotrama, in press.
• Sudha Neelam et al. Functional 20S proteasomes in mature human red blood cells. Experimental Biology and Medicine 236:580-591 (2011).
• Priscila Sato et al. Interactions between ankyrin-g, plakophilin-2, and connexin43 at the cardiac intercalated disc. Circ Res. 109(2):193-201 (2011).
• Justin R. Siebert et al. Chondroitinase treatment following spinal contusion injury increases migration of oligodendrocyte progenitor cells. Exp Neurol, in press.
• Justin R. Siebert and Donna J. Osterhout. Oligodendroglial Cells Express and Secrete Reelin. Anat Rec 294(5):759-763 (2011).
• Justin R. Siebert and Donna J. Osterhout. The Inhibitory Effects of Chondroitin Sulfate Proteoglycans on Oligodendrocytes. J Neurochem, in press.
• Brandy Verhalen and Stephan Wilkens. P-glycoprotein retains drug-stimulated ATPase activity upon covalent linkage of the two nucleotide binding domains at their C-terminal ends. J Biol Chem. 286(12):10476-82 (2011).
• Guangliang Wang et al. The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer's vesicle in zebrafish. Development 138(1):45-54 (2011).
• Benjamin J. Wolf and Michael F. Priniciotta. Viral and bacterial minigene products are presented by MHC class I molecules with similar efficiencies. Mol Immunology 48(4):463-71 (2011).
• Lauren Wood and Edward Shillitoe. Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1. Cancer Gene Ther., in press.
• Peng Zhang and Huaiyu Hu. Differential glycosylation of alpha-dystroglycan and proteins other than alpha-dystroglycan by LARGE. Glycobiology, in press.
• Zhang, Zhen*, Peng Zhang*, and Huaiyu. Hu. LARGE Expression Augments the Glycosylation of Glycoproteins in Addition to alpha-Dystroglycan Conferring Laminin Binding. PLoS.One 6.4 :e19080 (2011). (*These authors contributed equally)

2010

• Hajime Akada et al. Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease. Blood. 115(17):3589-97 (2010).
• Prabal Banerjee*, Lindsey Crawford* et al. Hematopoietic stem cells and retroviral infection. Retroviriology 7:8 (2010). (*Co-first authors)
• George Christophi and Paul T. Massa. Central neuroinvasion and demyelination by inflammatory macrophages following peripheral virus infection is controlled by SHP-1. Viral Immunology 22(6):371-87 (2010).
• Theodore Diakov and Patricia Kane. Regulation of vacuolar proton-translocating ATPase activity and assembly by extracellular pH. J Biol Chem. 30;285(31):23771-8 (2010).
• Amber Eade and Steven Youngentob. The Interaction of Gestational and Postnatal Ethanol Experience on the Adolescent and Adult Odor-Mediated Responses to Ethanol in Observer and Demonstrator Rats. Alcohol Clin Exp Res. 34(10):1705-13 (2010).
• Amber M. Eade et al. Ontogeny of the enhanced fetal-ethanol-induced behavioral and neurophysiologic olfactory response to ethanol odor. Alcoholism: Clinical and Experimental Research 34(2):206-13 (2010).
• David Fernandez and Andras Perl. mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus? Discov Med. 9(46):173-8 (2010).
• Adam Gerber et al. Reduced blockade by extracellular Mg(2+) is permissive to NMDA receptor activation in cerebellar granule neurons that model a migratory phenotype. J Neurochem.114(1):191-202 (2010).
• Kristin Giamanco et al. Perineuronal net formation and structure in aggrecan knockout mice. Neuroscience 170(4):1314-27 (2010).
• Steven Hicks et al. Ethanol-induced methylation of cell cycle genes in neural stem cells. J Neurochem 114(6):1767-80 (2010).
• Jing Hu and Eileen Friedman. Depleting Mirk kinase increases cisplatin toxicity in ovarian cancer cells. Genes & Cancer, in press.
• Jing Hu et al. Transient arrest in a quiescent state allows ovarian cancer cells to survive suboptimal growth conditions and is mediated by both Mirk/dyrk1B and p130/Rb2. International Journal of Cancer, in press.
• Lingyan Jiang et al. Decision making by p53: life versus death. Mol Cell Pharmacol. 1;2(2):69-77 (2010).
• Renee M. Laird and S.M. Hayes. Roles of the Src Tyrosine Kinases Lck and Fyn in regulating gamma delta TCR signal strength. PLoS ONE 5(1): e8899 (2010).
• Kaylen Lott et al. The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complex. J Biol Chem. 285(18):13769-80 (2010).
• Kaylen Lott and G. Cingolani. The importin beta binding domain as a master regulator of nucleocytoplasmic transport. Biochim Biophys Acta., in press.
• David J. Lubin et al. Folding of tetrameric p53: oligomerization and tumorigenic mutations induce misfolding and loss of function. J Mol Biol. 395(4):705-16 (2010).
• Akos Mersich et al. The formin FRL1 (FMNL1) is an essential component of macrophage podosomes. Cytoskeleton (Hoboken) 67(9):573-85 (2010).
• Jonathan Nardozzi et al. Molecular basis for the recognition of phosphorylated stat1 by importin alpha5. J Mol Biol. 402(1):83-100 (2010).
• Anna J. Nichols and Eric C. Olson. Reelin Promotes Neuronal Orientation and Dendritogenesis during Preplate Splitting. Cerebral Cortex 20(9):2213-23 (2010).
• Rebecca A. Oot and S. Wilkens. Domain characterization and interaction of the yeast vacuolar ATPase subunit C with the peripheral stator stalk subunits E and G. J Biol Chem. 285(32):24654-64 (2010).
• Jenny Rowe et al. Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice. Antiviral Research 86(3):276-85 (2010).
• Justin R. Siebert et al. Intrinsic Response of Thoracic Propriospinal neurons to Axotomy. BMC Neuroscience 11:69 (2010).
• Justin R. Siebert et al. Long descending cervical propriospinal neurons differ from thoracic propriospinal neurons in response to low thoracic spinal injury. BMC Neuroscience 11:148 (2010).
• Danielle A. Sliter et al. Activated inositol 1,4,5-trisphosphate receptors are modified by Lys48- and Lys63-linked ubiquitin chains, but only Lys48-linked chains are required for degradation. J. Biol. Chem., in press. [Epub ahead of print PMID:21071436]
• Hong Sun et al. Sequence and phylogenetic analysis of complete mitochondrial DNA genomes of two grasshopper species Gomphocerus rufus (Linnaeus, 1758) and Primnoa arctica (Zhang and Jin, 1985) (Orthoptera: Acridoidea). Mitochondrial DNA 21(3-4):115-31 (2010).
• Ravi Vaidyanathan et al. Regulation of cardiac inward rectifier potassium current (IK1) by synapse associated protein-97. J Biol Chem. 3;285(36):28000-9 (2010).
• Benjamin J. Wolf and M.F. Princiotta. Viral and bacterial minigene products are presented by MHC class I molecules with similar efficiencies. Mol Immunol, in press [Epub ahead of print]
• Jianxin Yu et al. Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migration. Cell Adh Migr. 4(3):342-7 (2010).
• Kimberly J. Zaccaria and J.S. McCasland. Transmission of food preference does not require socially relevant cues in mouse strain with low sociability.   Frontiers in Behavioral Neuroscience 4:164.
• Kimberly J. Zaccaria et al. Resistance to change and vulnerability to stress: Autistic-like features of GAP43 deficient mice. Genes Brain and Behavior 9:985-96.

2009

• Matthew Bentley and Thomas Poole. Neurovascular anatomy of the embryonic quail hindlimb. Anat Rec (Hoboken). 292(10):1559-68 (2009).
• George Christophi et al. Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype. Lab Invest 27 1-18 (2009).
• George Christophi et al. Interferon-beta Treatment in Multiple Sclerosis Attenuates Inflammatory Gene Expression Through Inducible Activity of the Phosphatase SHP-1. Clinical Immunology 6:24 (2009).
• George Christophi et al. Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease. J Virol. 83(2):522-39 (2009).
• Amanda C. Conta, Justin R. Siebert and D.J. Stelzner. Lack of Axonal Sprouting of Spared Propriospinal Fibers Caudal to Spinal Contusion Injury Is Attributed to Chronic Axonopathy. Journal of Neurotrauma 26: 1-19 (2009).
• Chad A. Corcoran et al. Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains. J Biol Chem. 284(33):21955-70 (2009).
• Charles Danko and Arkadii Pertsov. Identification of gene co-regulatory modules and associated cis-elements involved in degenerative heart disease. BMC Med Genomics. 28;2:31 (2009).
• Heba Diab et al. Subunit Interactions and Requirements for Inhibition of the Yeast V1-ATPase. J Biol Chem. 84(20):13316-25 (2009).
• Amber M. Eade et al. The consequence of fetal ethanol exposure and adolescent odor re-exposure on the response to ethanol odor in adolescent and adult rats. Behavioral and Brain Functions 5:3 (2009).
• Amber M. Eade and Steven L Youngentob. Adolescent ethanol experience alters immediate and long-term behavioral responses to ethanol odor in observer and demonstrator rats. Behavioral and Brain Functions 5:23 (2009).
• David Fernandez et al. Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol. 182(4):2063-73 (2009).
• Erik Kish-Trier and Stefan Wilkens. Domain architecture of the stator complex of the A1A0-ATP synthase from thermoplasma acidophilum. J. Biol. Chem. 284(18):12031-40 (2009).
• Erik Kish-Trier and Stefan Wilkens. Interaction of the Thermoplasma acidophilum A1A0-ATP synthase peripheral stalk with the catalytic domain. FEBS Lett. 6;583(19):3121-6 (2009).
• Adem Koksal et al. Dimeric quaternary structure of the prototypical dual specificity phosphatase VH1. J Biol Chem. 284(15):10129-37 (2009).
• Renee M. Laird and S.M. Hayes. Dynamics of CD3gammaepsilon and CD3deltaepsilon dimer expression during murine T cell development. Mol. Immunol. 47(2-3):582-9 (2009).
• Renee M. Laird and S.M. Hayes. Profiling of the early transcriptional response of murine gammadelta T cells following TCR stimulation. Mol Immunol. 46(11-12):2429-38 (2009).
• Sheena Claire Li and P. Kane. The yeast lysosome-like vacuole: endpoint and crossroads. Biochim Biophys Acta 1793(4):650-63 (2009).
• Ki Lui and Ying Huang. RanGTPase: A key regulator of nucleocytoplasmic trafficking. Journal of Molecular and Cellular Pharmacology. 3:148-156 (2009).
• Joanne Montalbano et al. Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation. J Biol Chem. 284:18129-42 (2009).
• Thien D. Nguyen and S.M. Taffet. A model system to study Connexin 43 in the immune system. Mol Immunol 46(15):2938-46 (2009).
• Adam S. Olia et al. Structural plasticity of the phage P22 tail-needle gp26 probed with Xenon gas. Protein Science 18(3):537-548 (2009).
• Margaret Pearce et al. An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem. 17;284(16):10433-45 (2009).
• Priscila Y. Sato et al. Loss of Plakophilin-2 Expression Leads to Decreased Sodium Current and Slower Conduction Velocity in Cultured Cardiac Myocytes. Circulation Research 105(6):523-6 (2009).
• Jesse B. Schallek et al. Stimulus-evoked intrinsic optical signals in the retina: Spatial and temporal characteristics. Investigative Ophthalmology Visual Science 50(10):4865-72 (2009).
• Jesse B. Schallek et al. Stimulus-evoked intrinsic optical signals in the retina: Pharmacological dissection reveals outer retinal origins. Investigative Ophthalmology Visual Science 50(10):4873-80 (2009).
• Michael Swartz et al. Left versus right atrial difference in dominant frequency, K(+) channel transcripts, and fibrosis in patients developing atrial fibrillation after cardiac surgery. Heart Rhythm. 6(10):1415-22 (2009).
• Jeff Ward et al. HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog. 5(10):e1000613 (2009).
• Jianxin A. Yu et al. Paxillin-Kinase-Linker (PKL) Tyrosine phosphorylation regulates directional cell migration. Mol. Biol. Cell 20:4706-4719 (2009).
• Jianxin A. Yu et al. The Focal Adhesion: A Network of Molecular Interactions. The Handbook of Cell Signaling, edited by Ralph Bradshaw and Edward Dennis. (2009)

2008

• Sarah A. Arrington et al. Concurrent administration of zoledronic acid and irradiation leads to improved bone density, biomechanical strength, and microarchitecture in a mouse model of tumor-induced osteolysis. J. Surg. Oncol. 97(3):284-90 (2008).
• Prabal Banerjee et al. Human T-cell lymphotropic virus type 1 infection of CD34+ hematopoietic progenitor cells induces cell cycle arrest by modulation of p21(cip1/waf1) and survivin. Stem Cells 26(12):3047-58 (2008).
• Tania Das Banerjee et al. A Comparison of Molecular Alterations in Environmental and Genetic Rat Models of ADHD: a pilot study. American Journal of Medical Genetics 147B(8):1554-63 (2008).
• George Christophi et al. Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. J Neurochem. 91(6):1439-49 (2008).
• George Christophi et al. SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients. Lab Invest. 88(3):243-55 (2008).
• Amanda C. Conta and D.J. Stelzner. Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. Spinal Cord 46(1):39-44 (2008).
• Chad Corcoran et al. Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies. Molecular Cancer Research 6(5):795-807 (2008).
• Miriam L. Donohue et al. Pulse-Train Stimulation for Detecting Medial Malpositioning of Thoracic Pedicle Screws. Spine 33 (12): E378-E385 (2008).
• Stacy Donovan and James McCasland. GAP-43 is critical for normal targeting of thalamocortical and corticothalamic, but not trigeminothalamic axons in the whisker barrel system. Somatosens Mot Res 25:33-47 (2008).
• David Fernandez and A. Perl. Metabolic control of T cell activation and death in SLE. Autoimmun Rev. 8(3):184-9 (2008).
• Jason A. Horton et al. Ontogeny of skeletal maturation in the juvenile rat. The Anatomical Record 291(3):283-92 (2008).
• Chad Hudson et al. Induction of IL-33 expression and activity in central nervous system glia. J Leukoc Biol. 84(3):631-43 (2008).
• Rosy Joshi-Mukherjee et al. Characterization of the molecular phenotype of two arrhythmogenic right ventricular cardiomyopathy (ARVC)-related plakophilin-2 (PKP2) mutations. Heart Rhythm. 5(12):1715-23 (2008).
• Katherine A. Kaproth-Joslin et al. Phospholipase Cd1 Regulates Cell Proliferation and Cell Cycle Progression from G1 to S Phase by Control of Cyclin E/Cdk2 Activity. Biochem J 415:439-448 (2008).
• Erik Kish-Trier et al. The Stator Complex of the A(1)A(0)-ATP Synthase-Structural Characterization of the E and H Subunits. J Mol Biol 375(3):673-85 (2008).
• Matthew Klos et al. Atrial Septopulmonary Bundle of the Posterior Left Atrium Provides a Substrate for Atrial Fibrillation Initiation in a Model of Vagally Mediated Pulmonary Vein Tachycardia of the Structurally Normal Heart. Circulation: Arrhythmia and Electrophysiology. 1:175-183 (2008).
• Shelley Kummer et al. Induction of human host cell apoptosis by Trichomonas vaginalis cysteine proteases is modulated by parasite exposure to iron. Microbial pathogenesis 44(3):197-203 (2008).
• Rebecca Lewandowski et al. RXP-E: a connexin43-binding peptide that prevents action potential propagation block. Circulation Research 103(5):519-26 (2008).
• Amanda Lindke et al. Generation and use of primary rat cultures for studies of the effects of ethanol. Methods in Molecular Biology 447:125-36 (2008).
• Gregory Mitrousis et al. Molecular basis for the recognition of snurportin 1 by importin beta. J Biol Chem. 283(12):7877-84 (2008).
• Anna Nichols et al. Comparison of slow and fast neocortical neuron migration using a new in vitro model. BMC Neurosci. 9:50, 2008.
• Adam S. Olia and G. Cingolani. A shifty stop for a hairy tail. Mol. Microbiol. 70(3):549-53, 2008.
• Catherine Ptaschinski and Rosemary Rochford. Infection of neonates with murine gammaherpesvirus 68 results in enhanced viral persistence in lungs and absence of infectious mononucleosis syndrome. J Gen Virol. 89(Pt 5):1114-21 (2008).
• Danielle A. Sliter et al. Mass Spectrometric Analysis of Type 1 Inositol 1,4,5-trisphosphate Receptor Ubiquitination. Journal of Biological Chemistry 283(51):35319-28, 2008.
• Rebecca M Smith et al. Nondestructive Optical Determination of Fiber Organization in Intact Myocardial Wall. Microsc Res Tech. 71:510-6 (2008).
• Margaret M. Stratton, Diana. M. Mitrea and S.N. Loh. A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding. ACS Chem. Biol. 3:723?732 (2008).
• Jeff Ward and Edward Barker. Role of natural killer cells in HIV pathogenesis. Curr HIV/AIDS Rep. 5(1):44-50 (2008 ).