Major Research Areas
Model Systems
Studies in classical model systems such as yeast, E. coli and fruit flies have formed the basis for many seminal biomedical discoveries of the last 30 years through combined use of classical genetics and modern molecular biology. The richness of resources available in some of these systems continues to grow at a rapid pace. Researchers at SUNY Upstate continue to utilize these and other classic model systems in the study of both basic molecular processes and complex diseases. Systems in use include the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe, the fruit fly Drosophila melanogaster, the Zebra fish Danio rerio, the frog Xenopus laevis, the flagellate Chlamydomonas reinhardtii, and transgenic mice in their laboratories.
Jeffrey Amack, Ph.D.
Assistant Professor
Genetics and cell biology of organ morphogenesis during embryonic
development. |
David Mitchell, Ph.D.
Professor
Regulation of ciliary dynein activity and assembly, and the role of the central pair complex in ciliary motility regulation. |
David Amberg, Ph.D.
Professor
Regulation of actin dynamics and analysis of genomic influences on actin function. |
M Golam Mohi, Ph.D.
Assistant Professor
Molecular mechanism of leukemia; study the effect of oncogenic mutations in pathogenesis of leukemia using mouse model. |
Xin Jie Chen, Ph.D.
Associate Professor
Mitochondrial biogenesis and inheritance, aging and aging-related degenerative diseases. |
Francesca Pignoni, Ph.D.
Associate Professor
Neurogenesis; Retinal Progenitor Cells Specification and Proliferation; Genetic Control of Stem Cell Identity and Maintenance; Genetic Pathways in RPE Formation; Disease Genes Analysis in Drosophila
|
Richard Cross, Ph.D.
SUNY Distinguished Professor
Bioenergetics, enzymology, structural biology, membrane protein function |
Thomas Poole, Ph.D.
Associate Professor
Vascular development and the alignment of growing nerves and blood vessels in quail and zebrafish embryos. |
Dipak Dube, Ph.D.
Professor
Molecular mechanism of cardiac myofibrillogenesis in vertebrates. |
Mark Schmitt, Ph.D.
Associate Professor
Ribonucleoprotein assembly and biogenesis; mitochondrial RNA import, mRNA degradation, cell cycle control |
Thomas Duncan, Ph.D.
Associate Professor
Bioenergetics, enzymology, structural biology, membrane protein function. |
Allen Silverstone, Ph.D.
Professor
How dioxins and estrogens and estrogenic compounds affect the immune system. |
Gerold Feuer, Ph.D.
Associate Professor
HTLV pathogenesis and Tax function; Humanized SCID mouse models of hematopoiesis; lentivirus vectors; KSHV/HHV-8 infection and pathogenesis; SCID-hu immune responses against HIV envelope |
Vladimir Sirotkin, Ph.D.
Assistant Professor
Mechanisms of the actin cytoskeleton assembly and role of myosin-1 during endocytosis in fission yeast. |
Patricia Kane, Ph.D.
Professor and Chair
Vacuolar H+ATPases (structure, function, assembly and regulation), cellular pH homeostasis, cellular stress responses, protein sorting, genomics, yeast as a model system |
Michael Zuber, Ph.D.
Assistant Professor
The molecular basis of retinal stem cell formation; regulating retinal stem/progenitor cell proliferation; using retinal stem/progenitor cells to heal the injured or degenerating retina. |
Barry Knox, Ph.D.
Professor
Visual transduction, Gene Expression, Membrane proteins |
Back to Research Areas List
Complete Faculty List
|
|
What's the
SUNY Upstate Difference?
Researcher Improves Bone Marrow Transplant Success Rate in MiceAt SUNY Upstate Medical University, researchers are dedicated to unlocking the mysteries of human health and illness.
William Kerr, a former Newman Scholar of the Leukemia & Lymphoma Society, brought more than $3.8 million in NIH funding this year to SUNY Upstate. Kerr investigates the role a novel gene (LRBA) plays in cancer cells, and studies a particular enzyme (SHIP) involved in the rejection of bone marrow and organ transplants. More >
|
