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Major Research Areas

Structural Biology

Relating protein structure and macromolecular complexes to their function in living cells is a major area of interest for many faculty. These groups encompass research on the structure of nucleic acids, membrane proteins, protein folding, assembly of macromolecular complexes, chromatin structure, and cytoskeletal architecture. Various tools employed are X-ray crystallography, NMR, cryo-electron microscopy, UV-spectroscopy, confocal microscopy, mass spectrometry, and computational analysis.

David Amberg, Ph.D.
Professor
Regulation of actin dynamics and analysis of genomic influences on actin function.
Michael Lyon, Ph.D.
Associate Professor
Age-related changes in the laryngeal muscles and vocal folds.
Edward Berry, Ph.D.
Assistant Professor
Biological energy transduction by membrane protein complexes, with emphasis on oxidative phosphorylation and photosynthesis.
David Mitchell, Ph.D.
Professor
Regulation of ciliary dynein activity and assembly, and the role of the central pair complex in ciliary motility regulation.
Scott Blystone, Ph.D.
Associate Professor
Actin Cytoskeletal Dynamics in the leukocyte inflammatory phenotype.
Arkadii Perzov, Ph.D.
Professor
Biophysical mechanisms of cardiac arrhythmias; fluorescence imaging.
Richard Cross, Ph.D.
SUNY Distinguished Professor
Bioenergetics, enzymology, structural biology, membrane protein function
Mark Schmitt, Ph.D.
Associate Professor
Ribonucleoprotein assembly and biogenesis; mitochondrial RNA import, mRNA degradation, cell cycle control
Thomas Duncan, Ph.D.
Associate Professor
Bioenergetics, enzymology, structural biology, membrane protein function.
Dennis Stelzner, Ph.D.
Professor
CNS regeneration, spinal cord injury research, and neural plasticity.
Steven Goodman, Ph.D.
Professor
Proteomic assessment of sickle cell severity.
Christopher Turner, Ph.D.
Professor
Regulation of cell migration by focal adhesion adapter proteins and their role in cancer cell metastasis.
Barry Knox, Ph.D.
Professor
Visual transduction, Gene Expression, Membrane proteins
Stephan Wilkens, Ph.D.
Associate Professor
Structure and Mechanism of Membrane Bound Transport Proteins
Stewart Loh, Ph.D.
Professor
Mechanism and kinetics of protein folding; protein-based molecular switches; protein engineering and design; structure and function of the p53 tumor suppressor.

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Researcher Improves Bone Marrow Transplant Success Rate in Mice

At SUNY Upstate Medical University, researchers are dedicated to unlocking the mysteries of human health and illness.

Dr. William Kerr

William Kerr, a former Newman Scholar of the Leukemia & Lymphoma Society, brought more than $3.8 million in NIH funding this year to SUNY Upstate. Kerr investigates the role a novel gene (LRBA) plays in cancer cells, and studies a particular enzyme (SHIP) involved in the rejection of bone marrow and organ transplants. More >

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