Major Research Areas
Cell Signaling
This research area investigates the signals emitted from a variety of cellular receptors following the binding of ligands. These receptors fall into several classes, controlling various cellular responses including signal transduction, cell migration, and cytoskeletal organization. The regulation and function of cytoskeletal elements and their interaction with cell surface receptors is a primary focus of several laboratories. Other areas of emphasis are the mechanism and consequences of calcium ion mobilization, signaling in neurons, light transduction, organogenesis, apoptosis, ion channels and steroid hormone action.
David Amberg, Ph.D.
Professor
Regulation of actin dynamics and analysis of genomic influences on actin function. |
M Golam Mohi, Ph.D.
Assistant Professor
Molecular mechanism of leukemia; study the effect of oncogenic mutations in pathogenesis of leukemia using mouse model. |
Robert Barlow, Ph.D.
Professor
Neural basis of visual behavior; computational models of neural coding; circadian and metabolic modulation of human visual sensitivity. |
Eric Olson, Ph.D.
Assistant Professor
Cellular and molecular mechanisms of cerebral cortex development. |
Scott Blystone, Ph.D.
Associate Professor
Actin Cytoskeletal Dynamics in the leukocyte inflammatory phenotype. |
Andras Perl, M.D., Ph.D.
Professor
Genes and Viruses Predisposing to Autoimmunity, Genetics, Apoptosis, Endogenous Retroviruses, Transaldolase |
Peter Calvert, Ph.D.
Assistant Professor
Molecular mechanisms of protein transport and localization in retinal neurons;
mechanisms of retinal degenerative diseases |
Francesca Pignoni, Ph.D.
Associate Professor
Neurogenesis; Retinal Progenitor Cells Specification and Proliferation; Genetic Control of Stem Cell Identity and Maintenance; Genetic Pathways in RPE Formation; Disease Genes Analysis in Drosophila
|
Eileen Friedman, Ph.D.
Professor
The role of the serine/theonine kinase Mirk/dyrk1B in cancers of the pancreas, ovary and colon. |
Thomas Poole, Ph.D.
Associate Professor
Vascular development and the alignment of growing nerves and blood vessels in quail and zebrafish embryos. |
Sandra Hayes, Ph.D.
Assistant Professor
Determining the roles of γδ T cell receptor structure and signaling potential in γδ T cell development and function |
Mark Schmitt, Ph.D.
Associate Professor
Ribonucleoprotein assembly and biogenesis; mitochondrial RNA import, mRNA degradation, cell cycle control |
Brian Howell, Ph.D.
Assistant Professor
The signal transduction events that regulate the functional organization of neurons in the brain, and the phenotypes caused by defects in the genes that encode these signaling molecules. |
M Saeed Sheikh, M.D., Ph.D.
Professor
Apoptotic signal transduction and cancer biology. |
Huaiyu Hu, Ph.D.
Associate Professor
Molecular studies of brain malformations. |
Allen Silverstone, Ph.D.
Professor
How dioxins and estrogens and estrogenic compounds affect the immune system. |
Ying Huang, M.D., Ph.D.
Associate Professor
Oncogenic signaling in cellular transformation and apoptosis; tumor suppressor genes. |
Vladimir Sirotkin, Ph.D.
Assistant Professor
Mechanisms of the actin cytoskeleton assembly and role of myosin-1 during endocytosis in fission yeast. |
Ziwei Huang, Ph.D.
Professor and Chair
Discovery and mechanism of action of new pharmacological agents for cancer, cardiovascular disease, neurodegeneration, infectious disease, and stem cell-based regenerative medicine.
|
Steven Taffet, Ph.D.
Professor
Regulation of intercellular communication in the heart, gene expression during macrophage activation |
Grant Kelley, M.D.
Associate Professor
Elucidating the regulation of PLC-epsilon and its role in glucose signaling and endothelial cell function in diabetes. |
Christopher Turner, Ph.D.
Professor
Regulation of cell migration by focal adhesion adapter proteins and their role in cancer cell metastasis.
|
Barry Knox, Ph.D.
Professor
Visual transduction, Gene Expression, Membrane proteins |
Mary Lou Vallano, Ph.D.
Professor
Neuronal survival and development. |
Paul Massa, Ph.D.
Professor
Regulation of cytokine-induced gene expression in oligodendrodcytes.
Regulation of innate immune responses in glial cells.
Unique control of NF-kappaB activation in neurons.
|
Andrea Viczian, Ph.D.
Assistant Professor
Mammalian retinal stem cells formation; molecular mechanism of retinal cell fate decisions; using cell replacement therapy to heal the blinded eye. |
Michael Miller, Ph.D.
Professor and Chair
Factors that regulate the proliferation, migration, and survival/death of neurons in the developing brain; models of fetal alcohol syndrome, autism, and attention-deficit hyperactivity disorder. |
Richard JH Wojcikiewicz, Ph.D.
Professor
Intracellular signaling via InsP3 receptors and the ubiquitin/proteasome pathway. |
David Mitchell, Ph.D.
Professor
Regulation of ciliary dynein activity and assembly, and the role of the central pair complex in ciliary motility regulation. |
Steven Youngentob, Ph.D.
Professor
In utero ethanol exposure and chemsensory systems plasticity, olfactory signal transduction, peripheral and central mechanisms of odorant quality coding. |
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Researcher Improves Bone Marrow Transplant Success Rate in MiceAt SUNY Upstate Medical University, researchers are dedicated to unlocking the mysteries of human health and illness.
William Kerr, a former Newman Scholar of the Leukemia & Lymphoma Society, brought more than $3.8 million in NIH funding this year to SUNY Upstate. Kerr investigates the role a novel gene (LRBA) plays in cancer cells, and studies a particular enzyme (SHIP) involved in the rejection of bone marrow and organ transplants. More >
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