Research Photos

Exclusive photos of CVR Research with the Xenopus Retina

Recording from photoreceptors in transgenic Xenopus tadpoles expressing selected mutations in rhodopsin that are known to cause retinal degeneration in humans. The outer segment of a rod or cone photoreceptor is gently drawn into the glass pipette to record light ö responses from rod or cone photoreceptors.

Recording from rods in Xenopus retina using suction electrodes

Left: The rod outer segment is drawn into the pipette from a piece of retina and currents recorded in response to light stimuli.

Right: Rods and cones isolated form a tadpole Xenopus retina following mechanical titration. An isolated rod is drawn into the suction pipette. Cones are smaller in size and have a characteristic oil droplet in their inner segments.

* (star) indicates the division between the outer and inner segments.