Segment A is an up-to-date overview of topics in cellular and
molecular biology. The lectures will provide a foundation on which many other
subjects in medical school will be based.
The key element in this segment is DNA (deoxyribonucleic acid).
The lectures will investigate DNA structure and function, including transcription
and translation into proteins, normal protein function and chromosome structure.
This will be followed by discussions on how changes in DNA (mutations) disrupt
the normal biological patterns and lead to a variety of disease phenotypes.
Patterns of inheritance, principles of genetics, and methods of genetic testing
will also be explored. Specific examples of human disease will illustrate
Goals of this segment:
In Segment B, the focus is on biological processes at the cellular
level. Information regarding cell to cell interactions, intracellular control
mechanisms, and cellular organelles will be covered. The function and control
of enzymes will also be discussed, including in depth analysis of specific
biological pathways such as glycolysis, electron transport, oxidative
phosphorylation and carbohydrate metabolism. An overview of how these processes
are important in developmental pathways is also provided.
One of the unique features of Segment B are the conferences.
Small groups of students will meet together with a facilitator to discuss
important aspects of molecular, cellular, and genetic issues for a
group of selected diseases. By investigating the molecular foundations
of these disorders, it is hoped the students will gain a better appreciation
diversity and intricacy of clinical problems and medical practice.
Goals of this segment:
Segment C will examine metabolism and nutrition. Key areas
of discussion include lipids, amino acids, vitamins, minerals, and cofactors.
Building on a basic understanding of these topics, clinical examples of obesity,
alcoholism, and atherosclerosis will provide a more detailed
understanding of how the individual pieces function
elements of human biology.
To further demonstrate the importance of these elements, Segment
C incorporates four clinical problem sessions to link didactic material to
Content maintained by: Constance Stein
All contents copyright 2003, SUNY Upstate Medical University
March, 13, 2009