General Information
A fungal infection that is endemic to the southwestern part of the
USA, usually in North American desserts. “San Joaquin fever”.
It is a dimorphic fungus found in dessert soil and is acquired by
inhaling airborne arthrospores and primarily effects immunocompromised
patients. Many patients are asymptomatic or have flu-like symptoms
that include cough, fever, chest pain, night sweats and weakness.
Is the most common fungal infection among immunocomprimised patients.
Cytology
Large thick-walled spherules (10-60 um)
Mature spherules that are round with double walls and contain
non-budding endospores
Endospores may be seen in background
May see necrosis
Atypical repair
Differentials
Histoplasmosis
Blastomyces
For more info go to: Coccidioidomycosis
