MSII Schedule
MLC II : Pathophysiologic Mechanisms of Disease (2008-2009) |
Aug | 25 | Introduction; Sepsis in-class exercise |
27 | Read: Harrison's Chapter 265 on sepsis; Compare hypovolemic, cardiogenic and distributive shock (Harrison's Table 266-2) Watch video |
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29 | Handouts: Organ system dysfunction & clinical enzymology and acute-phase phenomena | |
Sept | 3 | Read: Self-injection of endotoxin & personal experience w/ MODS and SIRS Watch videos Read: Lange Chapter 4: Infectious Diseases Submit assignment |
5 | Read & watch video: 100 years of sepsis Read & watch video: Surviving Sepsis Campaign & Eli Lilly , APC therapy Handout: Treatment of sepsis |
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8 | Read: Case 13-1996 (pneumonia and sepsis) | |
10 | Acid-base in-class exercise | |
12 | Hypothesis due | |
15 | Read: Case 21-2008 (chronic granulomatous disease) | |
17 | Read: Lange Chapter 3: Disorders of the Immune System |
Sept | 24 | Read: No respector of age |
26 | Assignment: Rheumatology mini-cases | |
29 | Read: Case 30-2004 | |
Oct | 1 | Read: Protecting against autoimmunity |
3 | Hypothesis due | |
6 | Read: Case 33-2007 | |
10 | Hypothesis due | |
15 | Read: Lange Chapter 6: Blood |
Oct | 22 | Read: Case 13-2008 |
24 | Read: Malignant lymphomas in autoimmunity and inflammation: A review of risks, risk factors, and lymphoma characteristics Hypothesis due |
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27 | Read: Case 32-2007 | |
29 | Read: Cancer Mini-Cases Set #1 | |
31 | Read: Cancer Mini-Cases Set #2 | |
Nov | 3 | Read: Metastatic Melanoma Package |
7 | Read: Cancer Immunology | |
10 | Read: Lange Chapter 5: Neoplasia |
Nov | 17 | Read: Case 36-2007 |
19 | Read: Constrictive pericarditis, Electrical alternans, Pulsus paradoxus | |
21 | Hypothesis due | |
24 | Assignment: Vasculitis outlines | |
26-28 | Assignment: Vasculitis mini-cases | |
Dec | 1 | Read: Case 9-2005 |
5 | Hypothesis due | |
8 | Read: Case 34-2006 | |
12 | Assignment: Valvular disease handout ; take-home quiz | |
15 | Read: Lange Chapter 10: Heart; 11: Blood Vessels | |
16 | Read: Lange Chapter 9: Lung |
Feb | 11 | Read: A 27 yo woman with a diagnosis of PCOS |
13 | Read: Metformin for the treatment of the polycystic ovary syndrome | |
16 | Read: Needle in a Haystack | |
18 | In-class exercise | |
20 | Read: Severe acute pancreatitis | |
23 | Read: A Stain in Time | |
25 | In-class exercise | |
27 | Read: The FDA and the Case Against Ketek Read: Severe Hepatotoxicity of Telithromycin |
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Mar | 2 | Read: Case 38-2005 |
4 | Watch video of case discussion Watch video pertaining to molecular mechanisms Review Powerpoint pertaining to molecular mechanisms Handout: Molecular mechanisms of preeclampsia Handout: Physiologic changes in normal pregnancy and in preeclampsia |
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6 | Read: The two stage model of preeclampsia: Variations on the theme Assignment: Hypotheses on normal pregnancy and preeclampsia |
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9 | Read: Lange Chapter 13: GI; 14: Liver; 15: Exocrine pancreas |
Mar | 23 | Read: Case 22-2006 |
25 | In-class exercise | |
27 | In-class exercise | |
30 | Read: A 74 year-old man with memory loss and neuropathy | |
April | 1 | In-class exercise |
3 | Read: Neurobiological aspects of psychotherapy | |
6 | Read: Leg weakness in a 66 year-old woman | |
8 | In-class exercise | |
10 | In-class exercise | |
13 | Read: Woman with Brugada syndrome and epilepsy | |
15 | Read: Optic neuritis | |
17 | Read: Pharmacokinetics and pharmacodynamics of quetiapine in a patient with a massive overdose | |
20 | Read: Lange Chapter 7: Nervous System |