MSII Schedule

MLC II : Pathophysiologic Mechanisms of Disease (Fall 2007)

Class meets on Mondays from 11:00 a.m. - 12:30 p.m., Wednesdays from 11:00 a.m. - 11:50 a.m. and Fridays from 11:00 a.m. - 12:30 p.m. in 1159 Weiskotten. * Occasional double Wednesday sessions meet from 10:00 a.m. - 11:50 a.m.

Case readings in BLUE, supplemental articles in ORANGE


Aug	27	Introduction; Sepsis mini-case
	29	Shock and multiple-organ dysfunction after self-administration of salmonella endotoxin [NEJM 328(20): 1457, 1993]; A personal experience with SIRS and MODS [Crit Care Med 24(8): 1417, 1996]
	31	Assignment: Sepsis terminology and organ system dysfunction
Sept	5*	Case 9-2004 [NEJM 350(12): 1236, 2004]
	7	Pandemic flu issues: H5N1 Influenza - continuing evolution and spread [NEJM 355(21): 2174, 2006]; Human H5N1 Influenza [NEJM 356(13): 1375, 2007]; Preparing for the next pandemic [NEJM 352(18): 1839, 2005]
	10	The last 100 years of sepsis [Am J Respir Crit Care Med 173: 256, 2006]; Assignment: Treatment of sepsis
	12	Surviving sepsis - practice guidelines, marketing campaigns, and Eli Lilly [NEJM 355: 1640, 2006]; Severe sepsis and therapy with activated protein C [NEJM 353: 1398, 2005]
	14	Sepsis hypothesis due
	17	Ring around the diagnosis [NEJM 354(18): 1937, 2006]
	19	Hypothesis due
	24	Unit I Examination
	26*	Rheumatologic disease workbook: mini-cases A-B (+ assignment: outline specified diseases)
	28	Rheumatologic disease workbook: mini-cases C-D (+ assignment: outline specified diseases)
Oct	1	Case 19-2007 [NEJM 356(25): 2631, 2007]
	3	Rheumatologic disease workbook: mini-cases E-F
	5	Hypothesis due
	10*	Case 15-2006 [NEJM 354(20): 2166, 2006]
	12	Hypothesis due
	15	Special cure [NEJM 351(19): 1997, 2004]
	17	Hypothesis due
	22	Unit II Examination
	24*	Cancer mini-cases: set #1
	26	Cancer mini-cases: set #2
	29	Case 4-2007 [NEJM 356(6): 612, 2007]
	31	A 42 year-old woman with breast cancer [Oncology 17(5): 614, 2003]
Nov	2	Hypothesis due
	5	Case 29-2006 [NEJM 355(12): 1263, 2006]
	7	Cancer mini-cases: set #3
	9	Hypothesis due
	12	Case 40-2006 [NEJM 355(26): 2772, 2006]
	16	Unit III Examination
	19	Vasculitis assignment and notes
	21	Saved by a test result [NEJM 330(5): 343, 1994]
	26	Undercover and overlooked [NEJM 351(10): 1014, 2004]
	28	Pericardial images mini-cases: Constrictive pericarditis, Electrical alternans, Pulsus paradoxus
	30	Hypothesis due
Dec	3	Case 15-2007 [NEJM 356(20): 2083, 2007]
	5	Gas exchange, expiratory flow obstruction and the clinical spectrum of asthma [Eur Respir J 9:1278, 1996]; Asthma mini-case
	7	Hypothesis due
	10	Search for the complication [NEJM 354(9): 957, 2006]
	12	Atrial fibrillation readings (Jalife package + NEJM catheter ablation study)
	14	Hypothesis due
	21	Unit IV Examination

Normal lab values at MGH [NEJM 351(15):1548, 2004]