Major Research Areas
Musculoskeletal Science
Faculty in the Musculoskeletal Science Research Center conduct basic and applied research in bone biology and skeletal biomechanics. Current areas of funded research include cellular and molecular biology of the growth plate, novel therapies for bone tumors, and strategies for enhancing the longevity of total joint replacement implants.
Timothy Damron, M.D.
Professor
Radioprotectant strategies: pediatric growth plate.
Treatment of Fractures in Pathology Bone,
Reconstructive Alternatives: Limb-Sparing Sarcoma Surgery,
Genetics of Pagetoid Osteosarcoma |
Jean Sanger, Ph.D.
Professor
Analysis of the assembly of the actin/myosin cytoskeleton in muscle and non-muscle cells. |
Dipak Dube, Ph.D.
Professor
Molecular mechanism of cardiac myofibrillogenesis in vertebrates. |
Joseph Sanger, Ph.D.
Professor and Chair
Cellular analysis of the formation of myofibrils, stress fibers, and cleavage furrows in living cells. |
Kenneth Mann, Ph.D.
Professor
Micro-mechanics of implant interfaces; damage evolution of joint replacements and biomaterials; in vivo models of tumor osteolysis and prediction of fracture risk; general orthopedic biomechanics. |
Joseph Spadaro, Ph.D.
Professor
Electromagnetic and mechanical regulation of bone physiology, skeletal growth and bone density. |
David Pruyne, Ph.D.
Assistant Professor
Biochemistry and cell biology of formins as actin cytoskeleton organizers, using Caenorhabditis elegans as a model system.
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Research Highlight
Richard Wojcikiewicz
Interim Chair, Pharmacology Department
Richard Wojcikiewicz, interim chair of the Pharmacology Department, was recently awarded a $260,589 RO1 grant from the National Institutes of Health for his study of intracellular calcium channels (IP3 receptors) and the ubiquitin/proteasome pathway. His work has relevance to clinical researchers studying cancer and neurodegenerative diseases.
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