Major Research Areas
Membrane Biology and Biophysics
Membranes and membrane proteins play central roles in signaling, compartmentalization, motility, and energy conversion in all cells, and many diseases are linked to dysfunction of membrane proteins. SUNY Upstate boasts some of the leaders in the field of proton pumps, energy conversion and cell motility. Approaches range from high-resolution structural studies of membrane proteins through X-ray crystallography, cryo-electron microscopy, and fluorescence spectroscopy to in vivo genetic approaches in model systems such as E. coli and yeast.
Robert Barlow, Ph.D.
Professor
Neural basis of visual behavior; computational models of neural coding; circadian and metabolic modulation of human visual sensitivity. |
Patricia Kane, Ph.D.
Professor and Chair
Vacuolar H+ATPases (structure, function, assembly and regulation), cellular pH homeostasis, cellular stress responses, protein sorting, genomics, yeast as a model system |
Edward Berry, Ph.D.
Assistant Professor
Biological energy transduction by membrane protein complexes, with emphasis on oxidative phosphorylation and photosynthesis. |
Barry Knox, Ph.D.
Professor
Visual transduction, Gene Expression, Membrane proteins |
Xin Jie Chen, Ph.D.
Associate Professor
Mitochondrial biogenesis and inheritance, aging and aging-related degenerative diseases. |
Arkadii Perzov, Ph.D.
Professor
Biophysical mechanisms of cardiac arrhythmias; fluorescence imaging. |
Richard Cross, Ph.D.
SUNY Distinguished Professor
Bioenergetics, enzymology, structural biology, membrane protein function |
Vladimir Sirotkin, Ph.D.
Assistant Professor
Mechanisms of the actin cytoskeleton assembly and role of myosin-1 during endocytosis in fission yeast. |
Thomas Duncan, Ph.D.
Associate Professor
Bioenergetics, enzymology, structural biology, membrane protein function. |
Joseph Spadaro, Ph.D.
Professor
Electromagnetic and mechanical regulation of bone physiology, skeletal growth and bone density. |
Steven Goodman, Ph.D.
Professor
Proteomic assessment of sickle cell severity. |
Stephan Wilkens, Ph.D.
Associate Professor
Structure and Mechanism of Membrane Bound Transport Proteins |
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Research Highlight
Richard Wojcikiewicz
Interim Chair, Pharmacology Department
Richard Wojcikiewicz, interim chair of the Pharmacology Department, was recently awarded a $260,589 RO1 grant from the National Institutes of Health for his study of intracellular calcium channels (IP3 receptors) and the ubiquitin/proteasome pathway. His work has relevance to clinical researchers studying cancer and neurodegenerative diseases.
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