Jean M Sanger, PhD
- Professor of Cell and Developmental Biology
Research Programs and Affiliations
- Biomedical Sciences Program
- Cell and Developmental Biology
- Research Pillars
- Analysis of the assembly of the actin/myosin cytoskeleton in muscle and non-muscle cells.
wild-type paxillin cells
Cells expressing wild-type paxillin (top) or paxillin lacking LD4 (bottom) were scratch-wounded followed by fixation 12 hours post-wounding. Tubulin (Green) and alpha-mannosidase II (Red) were labeled to note cell polarization and Golgi orientation. Cells expressing paxillin lacking LD4 are unable to reorient the Golgi towards the wound edge. From the lab of Christopher Turner, PhD.