Faculty Research Interests

Program Director/Department Chair: Joseph Sanger, PhD

  • Jeffrey Amack, PhD
    Associate Professor
    Research Interests: Genetics and cell biology of organ morphogenesis during embryonic development.
  • Scott Blystone, PhD
    Associate Professor
    Research Interests: Actin Cytoskeletal Dynamics in the leukocyte inflammatory phenotype.
  • Mira Krendel, PhD
    Assistant Professor
    Research Interests: Physiological functions of myosin motors and their roles in diabetic kidney disease and cancer
  • David Mitchell, PhD
    Professor
    Research Interests: Regulation of ciliary dynein activity and assembly, and the role of the central pair complex in ciliary motility regulation.
  • Donna Osterhout, PhD
    Assistant Professor
    Research Interests:

    Biology of oligodendroglia and myelin formation during development, remyelination and repair in spinal cord injury and MS\"

  • Thomas Poole, PhD
    Associate Professor
    Research Interests: Vascular development and the alignment of growing nerves and blood vessels in quail and zebrafish embryos.
  • David Pruyne, PhD
    Assistant Professor
    Research Interests: Biochemistry and cell biology of formins as actin cytoskeleton organizers, using Caenorhabditis elegans as a model system.
  • Jean Sanger, PhD
    Professor
    Research Interests: Analysis of the assembly of the actin/myosin cytoskeleton in muscle and non-muscle cells.
  • Joseph Sanger, PhD
    Professor and Chair
    Research Interests: Cellular analysis of the formation of myofibrils, stress fibers, and cleavage furrows in living cells.
  • Vladimir Sirotkin, PhD
    Assistant Professor
    Research Interests: Mechanisms of the actin cytoskeleton assembly and role of myosin-1 during endocytosis in fission yeast.
  • Christopher Turner, PhD
    Distinguished Professor
    Research Interests: Regulation of cell migration by focal adhesion adapter proteins and their role in cancer cell metastasis.
wild-type paxillin cells
wild-type paxillin cells


paxillin lacking LD4 cells
paxillin lacking LD4 cells

Cells expressing wild-type paxillin (top) or paxillin lacking LD4 (bottom) were scratch-wounded followed by fixation 12 hours post-wounding. Tubulin (Green) and alpha-mannosidase II (Red) were labeled to note cell polarization and Golgi orientation. Cells expressing paxillin lacking LD4 are unable to reorient the Golgi towards the wound edge. From the lab of Christopher Turner, PhD.

lab assistant examining bottles