Ongoing Research

Current Division of Cardiology Studies

GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment In PAtients with Atrial Fibrillation” (Phase II/III) 

  • This is a registry for patients who have been newly diagnosed with Atrial Fibrillation and are receiving treatment

FOURIER - A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination With Statin Therapy in Patients with Clinically Evident Cardiovascular Disease (SUNY REACH)  

  • Patients with statin intolerance may participate in the study of a new, novel medicine to help lower cholesterol

PARAGON - A multicenter, randomized, double-blind, parallel group, active-controlled study to evaluate the efficacy and safety of LCZ696 compared to valsartan, on morbidity and mortality in heart failure patients (NYHA Class II-IV) with preserved ejection fraction

  • A new medicine for patients with Congestive Heart Failure is being tested

PITCH-HF- Phosphodiesterase Type 5 Inhibition with Tadalafil Changes Outcomes in Heart Failure  

  • This trial uses an already approved medicine in a new way to slow the progression of Congestive Heart Failure

LightStudy - A multicenter, randomized, double-blind, placebo-controlled study assessing the occurrence of major adverse cardiovascular events (MACE) in overweight and obese subjects with cardiovascular risk factors receiving naltrexone SR/Bupropion SR

  • This study is designed to test the long-term safety of a weight loss drug in patients with known cardiac disease

Effect of Bariatric surgery on Ventricular Repolarization

  • SUNY Upstate is collaborating with SUNY Stonybrook to determine if weight loss after bariatric surgery will reduce dysfunction in the heart

Myocardial perfusion study to detect coronary microvascular abnormality in diabetic patients with nonfatal myocardial infarction

  • This study examines changes in blood vessels of the heart after treatment for a heart attack

RESCUE - Randomized Evaluation of Patients with Stable Angina Comparing Utilization of Diagnostic Examinations

  • We are comparing two methods of measuring heart function in patients who have stable angina (chest pain)

CADENCE 215 - A Multi-center, parallel-group, double-blind, placebo-controlled, randomized, ascending dose trial to determine the safety, tolerability, pharmacokinetics and efficacy of intravenous infusions of OPC-108459 administered to subjects with paroxysmal and persistent atrial fibrillation

  • A medicine is given to see if it will stop atrial fibrillation as well as currently used methods to treat that condition