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Patricia Kane, PhD

Patricia Kane, PhD
Chair and Professor

The central goals of scientists in the Biochemistry and Molecular Biology department are to research fundamental mechanisms in cells and organisms at the molecular level and to train the next generation of scientists. Read More...

Faculty Research Interests

David Amberg

Research Interests

Regulation of actin dynamics and analysis of genomic influences on actin function.

Alaji Bah
Alaji Bah, PhD
Assistant Professor

Research Interests

Elucidate the structure, dynamics and functions of intrinsically disordered proteins and protein regions (IDPs/IDRs) and their biological regulation by Post-translational modifications.

Audrey Bernstein
Audrey Bernstein, PhD
Associate Professor

Research Interests

Fibrosis; Scarring; Protein degradation; ubiquitin; integrins; cytoskeleton; patient-derived model systems

Dimitra Bourboulia
Dimitra Bourboulia, PhD
Assistant Professor

Research Interests

  • Extracellular kinase signaling
  • Extracellular chaperone function 
  • Targeting extracellular signaling networks in urological cancers

Peter Calvert
Peter Calvert, PhD
Associate Professor

Research Interests

Molecular mechanisms of protein transport and localization in retinal neurons; mechanisms of retinal degenerative diseases

Xin Jie Chen

Research Interests

Mitochondrial biogenesis and inheritance, aging and aging-related degenerative diseases.

Michael Cosgrove
Michael Cosgrove, PhD
Associate Professor

Research Interests

Epigenetic regulation of chromatin, Mixed Lineage Leukemia, structural biology, enzymology.

Richard Cross

Research Interests

Bioenergetics, enzymology, structural biology, membrane protein function

Thomas Duncan
Thomas Duncan, PhD
Associate Professor

Research Interests

Bioenergetics, enzymology, structural biology, membrane protein function.

Wenyi Feng
Wenyi Feng, PhD
Associate Professor

Research Interests

Chromosomal DNA replication origins (location, timing and regulation), replication fork integrity and checkpoint regulation, genomic instability and chromosome fragility in both the yeast and human genome

Diana Gilligan
Diana Gilligan, MD/PhD
Associate Professor

Research Interests

My research includes studies of the red blood cell membrane skeleton in patients with inherited hemolytic anemia

Steven Hanes

Research Interests

Gene expression in development and disease, RNA pol II regulation, homeobox genes, prolyl isomerases

Patricia Kane
Patricia Kane, PhD
Professor and Chair

Research Interests

Vacuolar H+ATPases (structure, function, assembly and regulation), cellular pH homeostasis, cellular stress responses, protein sorting, genomics, yeast as a model system

William Kerr

Research Interests

Transplant immunology and stem cell biology.

Barry Knox
Barry Knox, PhD
Professor and Chair

Research Interests

Visual transduction, Gene Expression, Membrane proteins

Bruce Knutson
Bruce Knutson, PhD
Assistant Professor

Research Interests

RNA polymerase I transcription (structure, assembly, regulation), nucleolar biology, macromolecular architecture, crosslinking, proteomics, bioinformatics, modeling, molecular genetics, biochemistry, model systems

Leszek Kotula
Leszek Kotula, MD/PhD
Associate Professor

Research Interests

Cancer biology, cell signaling, the role of actin cytoskeleton in tumor progression, mouse models of cancer

Vladimir Kuznetsov

Research Interests

Cancer systems biology, bioinformatics, big data and survival prediction analyses, predictive and personalized medicine, computational genome and transcriptome biology, non-B DNA structures, RNA:DNA hybrids, R-loops, G-quadruplexes, ncRNAs, clinical biomarker discovery and validation

Stewart Loh

Research Interests

Protein engineering, design, and folding

Frank Middleton
Frank Middleton, PhD
Associate Professor

Research Interests

Molecular basis of cortical-basal ganglia and cortical-cerebellar circuit formation and dysfunction in neurological and psychiatric disease.

Mehdi Mollapour

Research Interests

Post-translational regulation of the Hsp90 molecular chaperone machinery in cancer

Andras Perl
Andras Perl, MD, PhD
Distinguished Professor

Research Interests

Genes and Viruses Predisposing to Autoimmunity, Genetics, Apoptosis, Endogenous Retroviruses, Transaldolase

Francesca Pignoni
Francesca Pignoni, PhD
Associate Professor

Research Interests

Neurogenesis; Retinal Progenitor Cells Specification and Proliferation; Genetic Control of Stem Cell Identity and Maintenance; Disease Genes Analysis in Drosophila

David Pruyne
David Pruyne, PhD
Associate Professor

Research Interests

Biochemistry and cell biology of formins as actin cytoskeleton organizers, using Caenorhabditis elegans as a model system.

Mark Schmitt

Research Interests

Ribonucleoprotein assembly and biogenesis; mitochondrial RNA import, mRNA degradation, cell cycle control

Andrea Viczian
Andrea Viczian, PhD
Research Assistant Professor

Research Interests

Mammalian retinal stem cells formation; molecular mechanism of retinal cell fate decisions; using cell replacement therapy to heal the blinded eye.

Stephan Wilkens
Stephan Wilkens, PhD
Associate Professor

Research Interests

Structure and Mechanism of Membrane Bound Transport Proteins

Michael Zuber
Michael Zuber, PhD
Associate Professor

Research Interests

The molecular basis of retinal stem cell formation; regulating retinal stem/progenitor cell proliferation; using retinal stem/progenitor cells to heal the injured or degenerating retina.