WELCOME
Patricia Kane, PhD

Patricia Kane, PhD
Chair and Professor

The central goals of scientists in the Biochemistry and Molecular Biology department are to research fundamental mechanisms in cells and organisms at the molecular level and to train the next generation of scientists. Read More...

Funding

NIH Grants

5R01EY018421-07

CALVERT, PETER Mechanisms of signal-dependant photoreceptor protein localization transport External Icon

1R21AG047400-01A1

CHEN, XIN JIE Role of Ant1 over-expression and mitochondrial damage in progressive muscle degeneration External Icon

5R01AG023731-10

CHEN, XIN JIE Aging-related mitochondrial degeneration and degenerative diseases External Icon

3R01CA140522-05S1

COSGROVE, MICHAEL Molecular mechanisms for the assembly and regulation of MLL1 core complex External Icon

5R01CA140522-05

COSGROVE, MICHAEL Molecular mechanisms for the assembly and regulation of MLL1 core complex External Icon

5R01GM050322-21

KANE, PATRICIA Subunit structure and function in vacuolar H+-ATPases External Icon
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5R01HL072523-12

KERR, WILLIAM Role of SHIP in NK cell biology External Icon

5R01HL107127-04

KERR, WILLIAM Chemical inhibition of SHIP1 to facilitate allogeneic bone marrow transplantation External Icon

1K22CA184235-01

KNUTSON, BRUCE Molecular mechanism of RNA polymerase I transcription and dysregulation in cancer External Icon

5R01CA161018-02

KOTULA, LESZEK Mechanism of PIN development in ABI1/HSSH3BP1 KO Mouse External Icon

R01

LOH, STEWART Design of switchable proteins and enzymes

5R01AA006916-29

MIDDLETON, FRANK Experimental fetal alcohol syndrome External Icon

2R01AI072648-06A1

PERL, ANDRAS Metabolic control of T-cell lineage specification in SLE External Icon

1R03HD082609-01

PIGNONI, FRANCESCA DPP/BMP signaling in stem cells and development External Icon

1R01AR064760-01A1

PRUYNE, DAVID Formin dependent sarcomere assembly External Icon

5R01EY019517-04

VICZIAN, ANDREA Retinal progenitors for vision rescue External Icon

5R01GM058600-13

WILKENS, STEPHAN Structure of the vacuolar ATPase External Icon

5R01EY015748-07

ZUBER, MICHAEL Retinal stem cell culture and characterization External Icon

National Science Foundation (NSF)

HANES, STEVEN    Post-transitional regulation by the Bin3-7SK RNA Complex


Bayer

BERRY, EDWARD     Crystal Structure of Fungal Respiratory Complex 2
BERRY, EDWARD     Crystal Structure of Metazoan Respiratory Complex II


Sidney Kimmel Foundation

LOH, STEWART     Exploration of Thiosemicarbazones as mutant 053 reactivators


Carol Baldwin Foundation

LOH, STEWART     Rescue of Mutant p53 Breast Cancer


American Cancer Society

FENG, WENYI     Mechanism of Replication Stress-Induced Chromosome Fragility


Department of Defense

CDMRP Discovery Award FENG, WENYI Global Identification of Disease-Associated Genes in Fragile X Cells
CDMRP Idea Award FENG, WENYI Defining the Cause of Cancer-Specific CFSs in CML


March of Dimes

FENG, WENYI    Global Disease Gene Discovery of Fragile X-Associated Premature Ovarian Insufficiency