Faculty
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Gino Cingolani, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
4239 Weiskotten Hall
Upstate Medical University
750 East Adams Street
Syracuse, NY 13210
(315) 464-8744
Lab/Professional Web Site
| Education and Clinical Training
MS: 1995, University of Bari, Italy, Biochemistry
Ph.D.: 1999, European Molecular Biology Laboratory (EMBL), Protein Crystallography
Postdoctoral Fellow: 2003, The Scripps Research Institute, Cell Biology
Research Program and Department Affiliations
Biochemistry and Molecular Biology
Biomedical Sciences Program
Research Interests X-ray crystallography of large viral DNA-pumping enzymes and structural cell biology of nucleo-cytoplasmic transport
Publications - link to PubMed
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Additional Information
Selected Publications
Mitrousis, G., Olia, S.A., Walker and Cingolanix, G. (2008). Molecular basis for the recognition of snurportin 1 by importin b. J Biol Chem. In press
Zheng, H., Olia, S.A., Hankins, M., Andrews, S., Cingolani, G., and Gonen, T, (2008). A conformational switch in bacteriophage P22 portal protein primes genome injection. Molecular Cell. 29(3), 376-383.
Olia, S.A., Casjens, S. and Cingolani, G. (2007) Structure of Phage P22 Cell Envelope Penetrating Needle. Nature Struc Mol Biol. 14(12), 1221-1226.
Olia, S.A., Bhardwaj, A., Joss, L., Casjens, S., and Cingolani, G. The role of gene 10 protein in the hierarchical assembly of the bacteriophage P22 portal vertex structure. (2007) Biochemistry. 46(30), 8776-8784.
Bhardwaj, A., Olia, S.A., Walker-Kopp N, and Cingolani, G. Domain organization and polarity of tail needle gp26 in the portal vertex structure of bacteriophage P22. (2007) J. Mol. Biol. 371(2), 374-87.
Olia A, Al-Bassam J, Winn-Stapley DA, Joss L, Casjens S, and Cingolani G. Binding induced stabilization and oligomerization of portal closure factor gp4 in the assembly pathway of phage P22 tail (2006). J. Mol. Biol. 363, 558?576.
Chen MH, Ben-Efraim I, Mitrousis G, Walker-Kopp N, Sims PJ, Cingolani G.
Phospholipid scramblase 1 (PLSCR1) contains a non-classical nuclear localization signal with unique binding site in importin a (2005).
J Biol Chem., 280(11):10599-606.
Cingolani G, Bednenko J, Gillespie M, and Gerace L. Molecular basis for the recognition of a non-classical nuclear localization signal (NLS) by importin b. (2002) Molecular Cell, 10: 1345-1353.
Cingolani, G., Petosa, C., Weis, K., and Mueller, C.W. Structure of importin b bound to the IBB domain of importin b. (1999) Nature, 399(6733): 221-229.
This profile was last updated on 09/29/2008
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