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• B.A., Whitman College, 1984
• Research Assistant, Immunex Corporation, 1985-1987.
• Ph.D., Dartmouth Medical School, Department of Biochemistry, Laboratory of Dr. Charles N. Cole, 1992. Thesis Title: Isolation and characterization of essential genes of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA.
• Summer 1989 Cold Spring Harbor Yeast Genetics Course.
• January 1993-July 1996 Department of Genetics, Stanford University School of Medicine, Postdoctoral Fellow, The laboratory of David Botstein. Structure/Function Studies of the Yeast Actin-Cytoskeleton.

• Assistant Professor of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 1996-2002.
• Associate Professor of Biochemistry and Molecular Biology, SUNY Upstate Medical University, 2002-present.

• Graduated cum laude, 1983, Whitman College
• Phi Beta Kappa, 1983, Whitman College
• Ryan Fellow, 1991 and 1992, Dartmouth Medical School
• Outstanding Teacher Award 2004, College of Graduate Studies, SUNY Upstate Medical University
• President's Award for Excellence in Teaching 2004

• Life Sciences Research Foundation: June 1993-May 1996.
• NIH 5 Year RO1, "The Role of Aip3p in Regulating Actin Organization", May 1998-April 2003.
• AHA 3 Year, "The Roles of Old Yellow Enzyme in Actin Cytoskeleton Assembly", July 1999-June 2002.
• NIH 4 Year RO1, "Regulation of Actin Dynamics", June 2003-present.

• Prickett, K.S., Amberg, D.C., Hopp, T.P., (1989) A calcium dependent antibody for identification and purification of recombinant proteins, Biotechniques, 7, 580-589.
• Amberg, D.C., Goldstein, A.L., Cole, C.N., (1992) Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA, Genes Devel., 6, 1173-1189.
• Amberg, D.C., Fleischmann, M., Stagljar, I., Cole, C.N., Aebi, M., (1993) Nuclear PRP20 Protein is Required for mRNA Export, EMBO J., 12, 233-241.
• Bogerd, A.M., Hoffman, J.A., Amberg, D.C., Fink, G., Davis, L.I., (1994) nup1 mutants exhibit pleitropic defects in nuclear pore complex function, J. Cell Biol., 127, 319-332.
• Amberg, D.C., Basart, E., Botstein, D., (1995) Defining Protein Interactions with Yeast Actin in vivo, Nature Structural Biology, 2, 28-35.
• Li, O., Heath, C.V., Amberg, D.C., Dockendorff, T.C., Copeland, C.S., Snyder, M., Cole, C.N., (1995), Mutation or deletion of the Saccharomyces cerevisiae RAT3/NUP133 gene causes temperature-dependent nuclear accumulation of poly(A)+ RNA and constitutive clustering of nuclear pore complexes, Mol. Biol. Cell, 6, 401-417.
• Amberg, D.C., Botstein, D., Beasley, E.M., (1995) Precise gene disruption in Saccharomyces cerevisiae by double fusion polymerase chain reaction, Yeast, 11, 1275-1280.
• Heath, C.V., Copeland, C.S., Amberg, D.C., Del Priore, V., Snyder, M., Cole, C.N. (1995) Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene, J. Cell Biol., 131, 1677-97.
• Saavedra, C., Tung, K.-S., Amberg, D.C., Hopper, A.K. and Cole, C.N., Regulation of mRNA Export in Response to Stress in Saccharomyces cerevisiae, Genes and Devel., 10, 1608-20.
• Amberg, D.C., Zahner, J.E., Mulholland, Pringle, J.R. and Botstein, D., (1997) Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites, Mol. Biol. Cell, 8, 729-753.
• Amberg, D.C., (1998) Three-dimensional imaging of the yeast actin-cytoskeleton through the budding cell-cycle, Molec. Biol. Cell, 8, 3259-62.
• Rodal, A., Tetreault, J. Lappalainin, P., Drubin, D.G., and Amberg, D.C., (1999) Aip1p Interacts with Cofilin to diassemble Actin Filaments, J. Cell Biol., 145, 1251-64.
• Jin, H. and Amberg D.C., (2000) The Secretory Pathway Mediates Localization of the Cell Polarity Regulator Aip3p/Bud6p, Mol. Biol. Cell, 11, 647-661.
• Jin, H. and Amberg, D.C., (2001) Fission yeast Aip3p (spAip3p) is required for an alternative actin-directed polarity program, Mol. Biol. Cell, 12, 1275-1291.
• Evangelista M., Pruyne D., Amberg D.C., Boone C., and Bretscher A., (2002) Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast, Nat Cell Biol, 4(3):260-9.
• Yuzyuk, T., Foehr, M., and Amberg, D.C., (2002) The MEK kinase Ssk2p promotes actin cytoskeleton recovery after osmotic stress, Mol. Biol. Cell, 13, 2869-2880.
• Yuzyuk, T., Foehr, M., and Amberg, D.C. (2003) Actin recovery and bud emergence in osmotically stressed cells requires the conserved actin interacting mitogen-activated protein kinase kinase kinase Ssk2p/MTK1 and the scaffold protein Spa2p. Mol. Biol. Cell 14(7):3013-26.
• Bettinger BT, Gilbert DM, and Amberg DC. (2004) Actin up in the nucleus. Nat Rev Mol Cell Biol. 5(5):410-5.
• Haarer, BK and Amberg DC. (2004) Old Yellow Enzyme Protects the Actin Cytoskeleton form Oxidative Stress., Molec. Biol. Cell, 15, 4522-4531.
• Clark MG, Temply J, Haarer BK, Viggiano SC, Sept D and Amberg DC. (2006) A genetic dissection of Aip1p's interactions leads to a model for Aip1p-cofilin cooperative activities. Molec. Biol. Cell, 17, 1971-1984.
• Daniel JA, Yoo J, Bettinger BT, Amberg DC and Burke DJ. (2006) Eliminating gene conversion improves high-throughput genetics in Saccharomyces cerevisiae. Genetics, 172, 709-711.
• Haarer BK, Helfant AH and Amberg DC. (2007) Stable pre-anaphase spindle positioning requires Bud6p/Aip3p and an apparent interaction between the spindle pole bodies and the neck. Euk. Cell, May; 6(5): 797-807. Epub 2007 Apr 6.
• Farah ME and Amberg DC. (2007) Conserved actin cysteine residues are oxidative stress sensors that can regulate cell death in yeast. Molec. Biol. Cell, April 2007; 18 (4): 1359-1365.
• Haarer BK,Viggiano SC, Hibbs MA, Troyanskaya OG and Amberg DC. (2007) Modeling complex genetic interactions in a simple eukaryotic genome: Actin displays a rich spectrum of complex haploinsufficiencies. Genes and Devel., 21, 149-159. This article was featured on the cover and in a perspective published in the same issue.
• Bettinger BT, Clark MG and Amberg DC. (2007) Requirement for the polarisome and formin function in Ssk2p-mediated actin recovery form osmotic stress in Saccharomyces cerevisiae. Genetics, Apr; 175(4): 1637-48. Epub 2007 Jan 21.
• Bettinger BT and Amberg DC. (2007) The MEK kinases MEKK4/Ssk2p facilitate complexity in the stress signaling responses of diverse systems. J. Cell. Biochem., 2007 May 1; 101(1): 34-43
• Clark MG and Amberg DC. (2007) Biochemical and genetic analyses provide insight into the structural and mechanistic properties of actin filament disassembly by the Aip1p-cofilin complex in Saccharomyces cerevisiae. Genetics, 2007 May 4; [Epub ahead of print].

• Amberg DC, Burke D and Strathern J. (2005) Methods in Yeast Genetics. Cold Spring Harbor Press.

Book Chapters

• Amberg, D.C. and Botstein, D., (1996) Obtaining structural information about multi-protein complexes with the two-hybrid system. In "The Two-Hybrid System" (P.L. Bartel and S. Fields, eds.), pgs. 99-108, Oxford University Press, Oxford.
• Botstein, D., Amberg, D., Mulholland, J., Huffaker, T., Adams, A., Drubin, D., and Stearns, T., (1997) The Yeast Cytoskeleton. In "The Molecular and Cellular Biology of the Yeast Saccharomyces: Cell Cycle and Cell Biology" (J.R. Pringle, J.R. Broach, and E.W. Jones, eds.), pgs. 1-90, Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
• Cole, C.N., Heath, C.V., Hodge, C.A., Hammell, C.M., and Amberg, D.C. (2002) Analysis of RNA export, Methods in Enzymology, 351:568-87.