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Actin Interacting Proteins That Can Be Studied By Two-Hybrid

To see the differential interaction data for each ligand modeled on the structure of actin, point and click on the ligand of interest. Mutations that disrupt each interaction are marked in red.

Identified in a Screen:

     Known Actin Binding Proteins:

          Act1-Actin: 1 clone

          Pfy1-Profilin: 2 clones

          Cap/Srv2-Cyclase associated prot.: 3 clones

          Rvs167-Reduced viability on starvation: 1 clone

     Previously Identified Proteins:

          Glk1-Glucose kinase I: 2 clones

          RPS7-Ribosomal prot. S7: 1 clone

          Oye2-"Old Yellow Enzyme": 1 clone

     Previously Unidentified Proteins:

          Aip1-WD repeats: 1 clone

          Aip2-Flavin Binding?: 2 clones

          Aip3-Bud6: 4 clones

Identified Through Reconstructions

          Sac6-Fimbrin

          Cof1-cofilin

          Abp1-Actin Binding Protein 1