Colleen E O'Leary, M.D. Professor of Anesthesiology 4143 University Hospital Upstate Medical University 750 East Adams Street Syracuse, NY 13210

Education and Clinical Training

Clinical Specialty

Clinical Department/Section Affiliations

Clinical Interests

Research Program and Department Affiliations

Research Interests

Research Abstract

Investigations into the Sterility of Manually Assembled Extracorporeal Curcuits with Vented Reservoir. With B. Searles, D. Pettit, S. Alexander and A. Picone

Extracorporeal curcuits were assembled, left in an unmonitored area for 72 hours, then primed with lactated ringers solution as if for clinical use. The solution was circulated through the system and sampled for culture, using two different commercially available systems. A group of positive controls was collected by contaminating identical curcuits with a known concentration of E. Cloake to determine sensitivity of each culture method. Statistical analysis suggested that the chance of an assembled curcuit developing a detectable level of contamination within 72 hours of its dry assembly is insignificant. Based on these results, a change in hospital policy allowing the use of preassembled curcuits has been instituted which has resulted in considerable cost savings.

Comparative Effects of Fentanyl and Midazolam Sedation for Cataract Surgery on Cognitive Function in the Elderly. With S. Brangman and B. Esposito.

Fentanyl, a short acting narcotic, and midazolam, a short acting benzodiazepine, are frequently administered intravenously in low doses in the operating room to provide sedation for patients undergoing procedures under regional anesthesia. The non-acute effects of these drugs on cognitive function in elderly patients is unknown. Consenting elderly patients presenting for cataract extraction are given the Mini Mental Status Exam (MMS) preoperatively as a measure of cognitive function and are randomly assigned to receive fentanyl, midazolam or both drugs as sedation for surgery. The MMS is then administered 5-7 days post operatively.

Selected References

Yarmuch, J., R. D''Angelo, B. Kirkhart, C.E. O''Leary, et al. A comparison of remifentanil and morphine sulfate for acute postoperative analgesia after total intravenous anesthesia with remifentanil and propofol. Anesthesiology 87:235-43, 1997.

Beers, R.A., C.E. O''Leary and P. Franklin. Comparing the history-taking methods used during a pre-anesthesia visit: the HealthQuiz™ versus the written questionnaire. Anesth. Analg. 86:134-37, 1998.

This profile was last updated on 04/18/2005

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